The mushonga 'Manini': mirayiridzo kushandiswa

Kugadzirira "Mannino" mirayiridzo Chinyorwa anotsanangurwa inoshanda antidiabetic zvinodhaka kuti yokunyoresa INN (International Nonproprietary Names) zita iri "Glibenclamide". fuma iyi ndiyo huru simba ari gadziriro, icho zvinoberekwa vagadziri muchimiro mapiritsi, rairema 1.75 MG kana 3.5 MG. The mushonga sezvamunoita ebetsero yeimwe zvinosanganisirawo lactose monohydrate, silica, zvokudya chirungiso E 124 - cochineal dhayi, mbatatisi starch, gimetelloza.

The pharmacokinetic ehupfumi zvinodhaka inopiwa kuti glibenclamide - huru vanoshingaira fuma - iri huri Pfungwa iri micronized chimiro. Izvi zvinoita kuti tikwanise kuwedzera kupinda mwero zvinodhaka uye kuwedzera nzvimbo yaro kubvisa. Uyewo, tibudirire Absorção de Água zvinodhaka zvinoriumba kunoita methylhydroxyethylcellulose, inova chikamu kugadzirira "Mannino".

Mirayiridzo dzokushandisa vaudza kuti chirungiso akanga rakapotsa hapana zvainoita mamiriro muviri, asi, zvakadaro, zvinoita zvikuru yekudyidzana kuwedzera dzokugara nguva zvinoumba mushonga ari vakaparadzirwa chokutambudzika, kupfuura hubudirire yezviito zvake. Panguva danho iri wevasungwa zvinodhaka zviri yeplasma zvinoriumba kunowedzera matatu kashanu, saka pane rutapudzo mukuru uwandu shuga.

Medicament "Mannino" inechirevo zvose muperekedzi zvinoreva ane pfuma nokukurumidza woga kubva nemudumbu uye ayo micronized muchimiro glibenclamide kunoita anosunungurwa zvachose kubva ebetsero yeimwe mumuviri kwemaminitsi mashanu. Izvi zvinoita kuti tikwanise kutora mushonga chete usati wadya, nokuti 5 - 10 maminitsi pamberi. Yepamusoro wevasungwa kunoitika kugadzirira yapfuura, uye ayo chiito, naizvozvo, ndizvo vasiri. Kunyange zvazvo pfungwa, mashoko mawa kugamuchira zvokudya asina zvakawanda zvainoita Zvakaitwa zvinodhaka. Kugadzirira "Mannino" ane pamwero 100% bioavailability. Its hafu-upenyu muviri ndiwo avhareji rimwe nehafu kusvikira maawa matatu nehafu.

Time kugadzikana hypoglycemic mugumisiro glibenclamide anodzokororwa yose zuva.

The pharmacodynamic ehupfumi zvinodhaka, "Manini" mirayiridzo Chinyorwa anorondedzera nenzira iyi. Medikamet Izvi zvinogona kuvandudza secretion insulin yakakodzera kana kubvisa kubva Beta mumasero rwatata, uye mushonga kunonatsiridza jekiseni wanda, izvo zvinoitwa kurudziro kubva jekiseni Kanotokonya.

Uyezve, glibenclamide anokwanisa kuderedza kuitwa platelet kudzivisa myocardial ischemia. The mushonga anewo chokudzivirira Varwisei cardiac arrhythmias.

Sezvo iri zvakanaka yakasimbiswa, kuti chinodhaka nawo kuderedza ngozi yematambudziko kwechirwere cheshuga (mhando 2), izvo zvinosanganisira chirwere cheshuga cardiomyopathy, nephropathy uye retinopathy. Medicine "Mannino" mirayiridzo Chinyorwa rinotsanangura senzira yokuderedza padanho hwenyama mu zvirwere chokuita cheshuga.

Huru zvairatidza kuti kushandiswa glibenclamide - chirwere cheshuga ari mhando wechipiri, kana zvokudya kurapa akaratidza kusingagutsi mugumisiro. Mahwendefa "Manin" rinogona kushandiswa yakazvimirira kuchirapa mumiririri, uye sezvo chikamu mubatanidzwa mishonga nezvimwe Anti-shuga mishonga.

Zvinofanira kurangarirwa kuti ya mishonga uye dose unonyatsoratidza pakutsvaga chiremba kwakavakirwa munhu nzira kumurwere. Panguva kutanga kwekupwanyiwa kurapwa kuisa mishonga diki zvinodhaka kutarisira. Zvadaro, mumwe kururamiswa kwadzinoita chikumbiro, pamwechete rakasungwa zvokudya. Details of dose zvaiitwa inorondedzerwa mirayiridzo kushandiswa kwezvinodhaka.

Mukuru yokuona nayo dose kuchinja ndiyo padanho shuga.

Kugamuchira glibenclamide anogona kukonzera marwadzo, vakawanda chiri yomuropa. Zviratidzo ayo nokukundwa vangadikitira, tremor, nomusoro, chetsinga zvirwere, uye vamwe.

Contraindications nokuda kwezvinhu zvinodhaka ndivo hypersensitivity kuti hurongwa inefficiencies yechipiri kurapwa ne "Mannino", ketoacidosis, chadzo kusagadzikana itsvo chiropa.

Hakuna ruzivo rwakakwana pamusoro kushandiswa kwezvinodhaka vana, vane zera hakuiti pfuura makore 18.

Usashandisa mishonga panguva pamukaka uye panguva yepamuviri.

Achengetere mushonga unofanira kuva pane imwe tembiricha kwete kupfuura 25 C. Pane mamiriro ezvinhu kuchengetera pasherefu upenyu zvinodhaka riri 3 years.