"Indapamide" - mirayiridzo kushandiswa

Indapamide "- mushonga kungova boka thiazide diuretics vane antihypertensive kushanda. Medicine "Indapamide" kwakaratidza kuti kushandiswa pamberi neBP.

Pharmacological chiito "Indapamide" chinodhaka

Guide anoti kuti pharmacological ehupfumi ane mushonga wakabatana thiazide diuretics. Kuonana mushonga inokwanisa zvokusarudza rakavhara "nokunonoka" karusiyamu mugero kunoita kuti elasticity yacho arterial rusvingo, kwamakadarika pane zvinoderedza zvachose peripheral vascular nemishonga.

"Indapamide" haachinji carbohydrate muviri, izvo zvinofadza kuti varwere cheshuga, uye asingauyi kukanganisa wevasungwa kuti lipids mu plasma. Mahwendefa "Indapamide" kubatsira kuderedza hypertrophy kuti ventricle kuruboshwe, kwatindivadza vascular masvingo kuti norepinephrine uye angiotensin II, zvinoita kwetunhu prostaglandin E2, zvinoderedza kugadzirwa okisijeni radicals. Kazhinji rimwe 5-7 zuva kurapwa pamwe antihypertensive zvazviri kunoratidzwa, nemoyo chete dose masikati.

Pharmacokinetics "Indapamide" chinodhaka

Guide anoshuma kuti mushonga dzinoratidzwa yakakwirira bioavailability (93%) uye Absorção de Água mune nemudumbu. At mwero Absorção de Água yakafurira chikafu yaunodya. The soro wevasungwa zvinodhaka muropa zvinoumbwa mukati maawa imwe kana maviri pashure kutora mushonga mune mari 2.5 MG. The mushonga rinoita chiropa. 60% -80% mashoko ndiyo goho nomukombiyuta itsvo muchimiro metabolites, dzinenge 20% - kuburikidza ura. The mushonga haana kugona cumulating.

Zvairatidza "Indapamide"

Instruction prescribes mushonga kuti BP. Uyewo, kuti mushonga inokurudzirwa vaya vane chirwere usabuda mwoyo kukundikana.

Contraindications

"Indapamide" iri contraindicated mu:

- yakawedzera aikanganiswa nayo, uye dzimwe nomukaka zviri sulfonamide boka,

- anuria,

- hypokalemia,

- zvakakomba hepatic kana renal insufficiency,

- nguva lactation,

- chenjera zvokurwara pamusoro chepfungwa kutenderera,

- pamuviri,

- makore 18 (nokuda nokusviba)

- mawa kwokubatsira Pharmaceuticals kuwedzera nguva QT.

Zvokungwarira raitongwa mushonga pamberi gout uye chirwere cheshuga decompensation.

Dosing uye dosing zvinodhaka "Indapamide"

Guide rinokurudzira kunwa mapiritsi mukati, kwete mvura. 2.5 MG (daily dose) iri kushandiswa mangwanani kana masikati. Kana 1-2 mwedzi yawapiwa zvinodhaka hakuna akauya kutsvakwa kuchirapa Chaizvoizvo, dose hauna varumbidzwa kuwedzera nokuda mikana yakawanda nemishonga. Panyaya iyi, zvinodhaka kurapa kuti BP zano vanofanira kuwedzera mumwe mumiririri antihypertensive kuti hausi diuretic. Kana kubata maviri antihypertensive zvinodhaka dose "Indapamide" kunoramba kwakadaro.

ovhadhozi

Ovhadhozi zviratidzo kunoratidzwa muutera, kutyora gastrointestinal basa, kuda kurutsa, kurutsa, Urume uye electrolyte nenyonganiso. Mune zvimwe zviitiko zvinogona kuitika ovhadhozi kuti kufema mwoyo uye kunyanyisa richikwidibira ropa nevezera. In varwere cirrhosis chiropa anogona kuitika hepatic pakoma.

Kana ovhadhozi yaifanira kururamiswa kuti normalize mvura-electrolyte pachiyero; munhu gastric lavage uye symptomatic kurapa.

kudyidzana

Runogonesa zvinoita zvimwe zvinodhaka cheBP. Regai sangana ne mishonga ine lithium, vincamine, kaliyvyvodyaschie diuretics.

Side migumisiro mishonga "Indapamide"

Saizvozvowo, sezvo vanenge ovhadhozi. Zvichida mwoyo mutinhimira vachivavhiringidza nokuda kurasikirwa potassium. Uyewo, nemishonga kunogona kuitika simba, rakapinza kuderera kumanikidzwa kana yakamira, kuda kurutsa, abdominal marwadzo, manyoka, kugwinha, neutachiona. Mune zvisingawanzoitiki Muzviitiko, kungawedzera gout, chinyamunhari chinorwadza.