"Nolitsin" - mushonga unorwisa kana kwete? Mahwendefa "nolitsin" kubva chii?

Drug "nolitsin" - mushonga unorwisa kana kwete? Mhinduro yomubvunzo uyu akaoma, tichaita kuvapa chipo nyaya. Tinewo kukuudzai kuti, panguva ipi zvirwere zvaiona yakatarwa mumiririri kana aiva nemishonga uye contraindications, uyewo kukurukura sei zvikuru tinorasikirwa uye chii zvinhu zvinosanganisira nhengo dzaro.

Kavha, chimiro, Kuronga mishonga

Mahwendefa "nolitsin" (naro ivo kubatsira, isu acharondedzera pazasi) ane basa chirungiso akadai norfloxacin. Panyaya upiyona zvinoriumba, anoshandiswa sezvo magnesium stearate, anhydrous colloidal silica, microcrystalline cellulose, povidone uye mvura Yakanatswa.

Zvinofanira kucherechedzwa kuti anoshongwa vanoonekwa Mahwendefa gipromezola, propylene glycol, talc, yellow parara dhayi (E 110) uye titanium dioxide.

Kugadzirira "nolitsin", mitengo iri pasi apa, anogadzirwa mhoni mahwendefa 20 kana 10, anoiswa mukati mabhokisi makadhibhokisi.

The pharmacological ehupfumi zvinodhaka

Medicament "nolitsin" - mushonga unorwisa kana kwete? Varwere vakawanda vanobvunza mubvunzo uyu vanachiremba dzavo. Sezvo chikazozikamwa, zvinoshingaira chirungiso ichaongororwa zvinodhaka norfloxacin. Kunochinja ane inorwisa utachiona zvainoita okuva staphylococci uye neisserial, Klebsiella, Enterobacteriaceae, Escherichia coli coli, Legionella, Chlamydia, Salmonella, Shigella, uye zvimwe zvirwere nevamiririri.

The mashandiro zvinodhaka chiito kwakavakirwa kukurukurirana pamusoro kushingaira fuma ine DNA gyrase (i.e. tusingaoneki enzayemu). Yakadaro simba inotungamirira destabilization DNA cheni, uye rufu dzairamba kwemabhakitiriya.

Sezvo mushonga "nolitsin" - mushonga unorwisa kana kwete? Kubva ose pamusoro, tinogona zvakachengeteka kugumisa kuti mushonga uri mushonga unorwisa mumiririri sezvo ane kunambwa anokuvadza tusingaoneki.

The inorwisa utachiona mugumisiro mahwendefa hunogara kwemaawa anenge 12. Kazhinji, kugadzirira kwakadaro kunoratidzwa zvirwere kuti zvinokonzerwa enterococci nezvimwe mycobacteria.

Pharmacokinetics zvinodhaka

Zvino munoziva kuti ndiyo mushonga "nolitsin". Inorwisa mabhakitiriya kana kwete mishonga, isuwo kuwanikwa. Zvino ndinoda kukuudzai kuti pane kwaswedera pakati mari kupinda systemic riparadzirwe.

Maererano nemashoko vemishonga, zvinoshingaira wemafuta zvinodhaka izvi zvikuru nokukurumidza kunakidzwa nema- ino. Parainge kuwanda vakachengeta kare pashure maawa 1-2 mushure ingestion mahwendefa. The bioavailability zvinodhaka ndiko 30-40%. Inenge 15% yezviri fuma vakasungwa mapuroteni eplasma.

The mushonga rinowanika kuchinja maererano renal hurongwa. Uye chete chiduku chikamu anoenda kuburikidza zvomudumbu turakiti.

In vanhu vane renal vanotaura mashoko pharmacokinetic ehupfumi zvinodhaka kungaratidzwa zvimwe.

Zvairatidza kuti kushandiswa kwezvinodhaka

Mune zvimwe zviitiko, taurira "nolitsin" piritsi? Kubva zvavari kubatsira? Maererano mirayiridzo, kufunga medicament nachiremba kurapa pamusoro urogenital zvirwere zviri infective kana anogumbura hunhu:

• urethritis;
• chisingaperi prostatitis kwemabhakitiriya mavambo;
• endometritis;
• cystitis;
• cervicitis;
• nyore mwandabvu;
• pyelonephritis.

Ndezvipi zvimwe mishonga inoshandiswa "nolitsin"? Zvairatidza kuti kubvuma zvinodhaka angava sezvinotevera:

• shigellosis;
• kwemabhakitiriya gastroenteritis;
• kudzivirira manyoka;
• salmonellosis;
• kudzivirira septic yematambudziko vari varwere neutropenia.

Contraindications

Kugamuchirwa "nolitsin" harifaniri kubvumirwa pasi zvinotevera ezvinhu:

• chepfungwa ropa zvitengeswa;
• kusada fluoroquinolones;
• zvipusha urwere;
• vana;
• changed (atherosclerotic) mu cerebral midziyo;
• vachiberekwa kushaikwa G6PD enzayemu;
• neutachiona kuti asipurini.

Zvinofanira kucherechedzwa kuti mushonga mu mubvunzo harifaniri kushandiswa chiremba tsika.

Sei kutora "nolitsin"?

Tora "nolitsin" Mahwendefa vanofanira kuva mukati, kunwa mvura pachena.

In zvirwere zviri urogenital hurongwa zvinodhaka raitongwa kaviri pa 400 MG daily. Ya kurapwa uyu mazuva 7-10.

Mabatirwo nyore cystitis rinoitwa mazuva 4-7.

Idzokororo Urinary turakiti zvirwere (chirwere hunhu) inofanira kubatwa kwevhiki 12. Panyaya rikwanise gastroenteritis kwemabhakitiriya mavambo, kuti panguva chirwere zvinodhaka hwakadaro ushandiswe kaviri daily 400 MG kwemazuva mashanu.

Kana proctitis, cervicitis, urethritis pharyngitis uye piritsi wakatorwa kamwe mari 400 MG.

Zviratidzo ovhadhozi

Pashure pokugamuchira yakakwirira mishonga zvinodhaka murwere rinoratidza zvinotevera zviratidzo: zvakakomba kurutsa, dzungu, kuda kurutsa, hope, ziya chando. The kurapa mamiriro ezvinhu akadaro zvinosanganisira gastric lavage uye tichiita rokumanikidzirwa diuresis.

Nenjodzi pashure ingestion mahwendefa

Pane divi migumisiro pashure kutora zvinodhaka, "nolitsin"? Instruction anodzokorora vanachiremba vanoti zviitiko zvinotevera rwakashata:

• svoto;
• hypercreatininemia;
• kurutsa;
• glomerulonephritis;
• shungu manakiro mumuromo;
• polyuria;
• epigastric kurwadziwa;
• urethral svota;
• vachidya zvirwere;
• crystalluria;
• chemanyoka urwere;
• dysuria;
• pseudomembranous enterocolitis;
• albuminuria;
• wakawedzera alt uye AST.

Uyewo, varwere kungaita nomusoro, aone zvinhu zvisipo, kuvaviwa, arrhythmia, vasculitis, kushaya hope, tachycardia, edema, syncope, urticaria uye erythema

Very kusingawanikwi muvanhu kutora zvinodhaka "nolitsin", akanyora kuchinja parameters ropa, candidiasis, arthralgia, kuderera hematocrit, kutya chiedza uye chemosis.

zvinodhaka kwavatori

Nyaya mumiriri kunoderedza kubudirira rekugadzirira se "Nitrofuran", uye inowedzera wevasungwa pakati anticoagulants uye "Ciclosporin". Zvinofanira kucherechedzwa kuti norfloxacin kunoderedza zvachose Clearance (anenge ¼) kuti theophylline.

Apo vagari kushanda mahwendefa "nolitsin" zvinodhaka kuti kuderedza zvipusha chikumbaridzozve, varwere vanogona yakakura pfari.

Panguva iyoyowo kushandisa zvinodhaka antihypertensive kwave rakapinza ichidonhedzera kuitiswa.

Antacids kuderedza Absorção de Água kuti "nolitsin".

Kushandisa mishonga dzaizopiwa kungopa yokutindivadza, zvinoda chaiwo kudzora mwoyo zvazvingava, BP uye mwoyo ushande.

nhungamiro chaiwo pamusoro pokushandiswa mishonga

Pamberi kugadzwa asingaurayiwi yomuchipatara "nolitsin" vanofanira kuona aikanganiswa pakati kasvisto kune basa wemafuta chezvinodhaka.

In chirwere chakadai, sezvo pyelonephritis, aiona medicament anofanira kuzviita pamwe chete zvinodhaka kuti chirimwa mavambo (somuenzaniso, ne "kanefron").

Panguva kurapwa, varwere vanofanira kugamuchira yakawanda mvura (kudzorwa weti goho).

Panguva mushonga ne "nolitsin" unodikanwa kuti vasangoramba kuona zvakananga chezuva.

Kana murwere ane kurwadziwa ari nemarunda kana tenosynovitis nezviratidzo wakacherechedza, mushonga inofanira pakarepo kuregwa.

Panguva kurapwa pamwe norfloxacin anofanira kudziviswa zvikuru chaiko nesimba.

Drug "nolitsin": mutengo uye analogues

Analogues kunoreva vaiona ndedzinotevera Formulations: "Lokson-400", "Norfatsin", "Norbaktin", "Sofazin", "Norilet" uye "Renor".

Mutengo "nolitsin" hwendefa kunobva mari chete rongedza: 10 zvidimbu - 150 rubles, 20 zvidimbu - 305 rubles.

mishonga Reviews

Reviews kuti "nolitsin" gadziriro akanaka kune mukuru pamwero. Hazvina kunyanya kubudirira cystitis. Maererano varwere kutora mushonga wacho nokukurumidza anobvisa zvose zvinoitika zviratidzo akati chirwere (marwadzo, chinyamunhari chinorwadza, kuita weti kakawanda).

Saka, zvakanaka kuti kugumisa kuti "nolitsin" medicament chinopa inobudirira uye chipa mushonga nokuda pakurapa zvirwere genitourinary hurongwa. Muchiitiko chino, hazvibviri tisingatauri chokwadi kuti vamwe varwere vanoti chokushandisa ichi anokwanisa kukonzera chaizvo vakawanda nenjodzi. Panyaya iyi, mushonga zvinofanira kutorwa chete mushonga uye, pashure tsanangudzo kudzidza mirayiridzo.