The mushonga 'Tamoxifen'. Instruction kuverenga

The mushonga "Vero Tamoxifen" rinoshandiswa kwenguva refu. mishonga iyi semhosva zvokusarudza inonzi estrogen Kanotokonya modulators. Medicine kupinda muropa, richiparadzirwa munyika muviri.

Nokuda kuti nzira "Tamoxifen" rine kunyora nezvavo estrogenic basa, ine simba chaizvo stimulatory zvainoita masero. With kukwanisa adzikatidza vakasununguka receptors pamusoro pemvura bundu masero, zvinodhaka kuchititadzisa ari kweiyi mahormone neoplasm. Saka, mushonga anooneka antiestrogenic kushanda.

The mushonga "Tamoxifen" muperekedzi rinotsanangura senzira kusarudzwa namamota ari mammary shwanu vakadzi premenopausal. The mushonga anogadzwa uye vakadzi postmenopausal. Zvisinei, panguva iyi kuti medicament shoma inobudirira kupfuura FIs (inhibitory chiito) aromatase (dzakananga enzayemu).

The mushonga "Tamoxifen" Chinyorwa anokurudzira kuti kenza yeprostate nenhongo zamu, kenza ganda, yemazamu, ovaries vakadzi. The mushonga ushandiswe uye hadzi kushaya mbereko. Kugadzirira "Tamoxifen - hexane" iri anowedzera akaratidza ive adjunct mushure kuvhiya dambudziko zamu carcinoma.

The medicament rinogona kushandiswa senzvimbo prophylactic. Saka, mushonga "Tamoxifen" anokwanisa rakavhara inonzi estrogen Kanotokonya uye kenza yemazamu mumasero utano. Izvi zvinobvumira kuti kupa mushonga varwere rurefu kubatwa kuti kenza, asi asingaiti kutambura kwavari pamberi.

Kazhinji, ya zvinodhaka kutarisira "Tamoxifen" - makore mashanu. Zvakakosha kuona pano kuti panyaya kugadzwa mushonga mu metastatic kukura kenza, rakundwa zvakawanda zvainoita kwazvinogumira.

The chipimo chemushonga rinoreva "Tamoxifen" muperekedzi rinokurudzira akagara nomumwe. Yemanyorero nachiremba maviri kusvika makumi mana milligrams pazuva.

The mushonga "Tamoxifen" kurayira haabvumiri kugamuchira panguva pamuviri.

Kushandisa mishonga inogona kukonzera zvinoverengeka varwadziwe. Kunyanya, nzira kukonzera kuora mwoyo, dzungu, ziso nenyonganiso, kuzvimba mutsinga. Mune zvimwe zviitiko, pangava nemusoro, chokubuda (kusangana nekutsi kwemukadzi), yokubereka kuvaviwa, mapundu. The inonyanya nemishonga zvinosanganisira kuda kurutsa, fivha, marwadzo ari maronda uye mapfupa.

Zvinofanira kucherechedzwa kuti pamusoro nguva kubudirira zvinodhaka "Tamoxifen" simba. Somugumisiro, mushonga haasi kukwanisa kushanda rokuchinja okutanga masero. Mune zvimwe zviitiko, zvainoita kunoshandurwa. Nemamwe mashoko, kuti mushonga anotanga kuita inonzi estrogen uye zvinowedzera kukura masero, pane kudzvanyirira pavo. Kazhinji izvi ari chokuita mano inonzi estrogen Kanotokonya kushandura saizi yayo, arambe achirema, chimiro kana kushanda. Uyezve, kenza chityu angaperekedzwa kuvapo zvose kemikari kunaka uye masero kemikari-akanaka. Panyaya iyi, mushonga "tamoxifen" pazvinhu sero rimwe chete unoshanda, uye pachinhu vamwe - kwete. Saka, vamwe receptors vanobvuma, nepo vamwe vari nemishonga zvinodhaka.

Kana post-kuenda kumwedzi murwere mushonga, uye pashure maviri kana matatu apfuura, zvinova basa, chiremba kunowanzoitwa mukadzi ari aromatase FIs.

Zvinofanira kucherechedzwa kuti mamwe marapiro (semuenzaniso, mahormone) havagoni kutsiva dzimwe nzira dzokurapa. Zvakakosha kuyeuka kuti kazhinji kukosha neimwe nzira chiito kunowedzerwa zvikuru kana revatema kushanda.

Mumazana kurapwa nokushandiswa kwezvinodhaka "Tkamoksifen" vanofanira zvakanyatsorongwa akuteerere mufananidzo ropa.