The mushonga "Hydroxyzine": mirayiridzo kushandiswa, analogs uye wongororo

Diphenylmethane nomukaka zviri pafuma inzira "Hydroxyzine". User chikumbiro inoti nefuma chinhu chena wakanaka upfu, soluble mumvura uye odorless. 374,9 magiramu por nhuta ndiyo samolecular kurema mukomboni.

boka Clinico-pharmacological

The mushonga une kunyaradza, anxiolytic mugumisiro. Izvi anotsanangura inhibitory sei nezvebasa zvimwe zvivako subcortical zvomusoro tsinga uyewo ichivharira chiito pamusoro nechepakati H_1-histamine uye M-cholinergic receptors.

"Hydroxyzine" chinodhaka analogues vane iziviswe nyaradzo uye vanyoro anxiolytic basa. Iva kunobatsira zvikuru pamusoro zvishande mano, kunonatsiridza kutarisirwa uye ndangariro. Vanoziva remangwana kana zvinofunga nedoro uye kupindwa muropa hakuitiki pashure kushandiswa kwenguva yakareba pamusoro chirwere haina kuchengetwa. Kunoonekwawo anticholinergic, antihistamine, antispasmodic chiito. "Hydroxyzine" Unotsigira kurwadza kwacho kwezvinhu wakatsetseka tsandanyama, nokudaro vachikonzera bronchodilatory uye marwadzo anokonzerwa, ane antiemetic chiito uye usinganyanyi inhibitory kukanganisa gastric secretion. . Mikoko, dermatitis, eczema, kuvaviwa, etc. zvinoderedza panguva kurapa rinoreva "Atarax" (hydroxyzine - kushingaira fuma).
Guide rinoti kuti nyaradzo kunokwanisika, kazhinji mukati 10 kusvika ku45 pashure ingestion (zvichienderana chimiro zvinodhaka), Anti histamine - awa rimwe pashure ingestion. In varwere vanenge chiropa chirwere, imwe antihistaminic mugumisiro angatarisirwa mumaawa 96.

Not anozivikanwa mutagenic uye carcinogenic zviito zvinodhaka.

Pharmacokinetics

Kana anwa mushonga yava kunyura kubva nemudumbu, C_max ikoko maawa maviri. Kugadzirira "Hydroxyzine" ichipfuura placenta uye ropa-pfungwa chipingamupinyi (ukuru wevasungwa munguva fetus munyama kupfuura rwaamai munyama). In nedanho hepatic muviri akaumba cetirizine - guru metabolite. Ukoshi T_1 / 2 zvisinei makore murwere uye anogona kuva maawa 7 vana vane makore makore 2-10, maawa 20 kuti vakuru, maawa 29 vakwegura uye vakwegura; vari varwere chiropa chirwere anogona ngazviwedzerwe maawa 37. kubviswa rinoitwa vakawanda nokuda itsvo (0,8% muna yaro yokutanga chimiro).

zvairatidza

"Hydroxyzine Hydrochloride" rinoshandiswa kuna:

• kubvisa kufunganya uye hyperexcitability pakati tsinga;
• panguva akasarinwa vanhu vachitambura doro kuyanzva;
• yokurapwa pamusoro psychoneurotic zvirwere;
• sechikamu nzwisisika kurapwa mune postoperative nguva uye pashure mamwe makuvaro;
• premedication;
• kuderedza womukati kunetseka, generalized kufunganya, kuchinja kupora pezvakaitwa, pakurapa systemic zvirwere;
• kubvisa zviratidzo eczema, itchy dermatosis, urticaria, atopic dermatitis;
• nokuti antiemetic chiito yakaratidza.

Contraindications kuti mushonga "Hydroxyzine Canon"

Reviews kuvarapi zvinoratidza kuti mushonga hauna varumbidzwa kugamuchira:

• varwere vanenge yemaziso;
• prostate hypertrophy (yeprostate);
• varwere maari kwawedzerwa kufenda basa;
• varwere myasthenia gravis;
• Varwere vanenge chirwere renal uye hepatic kukundikana;
• varwere dementia.

The mushonga iri contraindicated mu:

• Vakadzi vane pamuviri;
• varwere porphyria;
• achiyamwa nguva (nguva kurapwa vanofanira kusiya achiyamwa mukaka waamai);
• sema kuratidzwa kuti vanoumba chinoita (sapamazuva iwayo zviitiko apo kare akacherekedza hypersensitivity kune dzimwe rinobva cetirizine, aminophylline, piperazine kana ethylene diamine);
• panguva basa uye pakusununguka.

About nemishonga

Varwere vangatambura nehope, kupemberera mukuru muutera, dzungu uye kutemwa pakutanga zvinodhaka mishonga "Hydroxyzine". Reviews wevarwere kubatwa mumiririri uyu, vanoti zvinotevera nemishonga:

• neutachiona, palpitations, kuda kurutsa,
• Urinary chengetedzo, uye kupatira;
• kuoma kwezvinhu zvinoonekwa mucous membranes, vakawedzera vangadikitira;
• madzerere (Pamwewo kutyorwa pekugara);
• BP, vakawedzera chiropa enzayemu basa;
• vanogona bronchospasm.

Very isingawanzowanikwi kuratidzwa nezvipusha, tremor uye nekuvhiri- ngika, ataxia, gangaidzo kurudziro uye kwakawedzera gwenya basa iri kushandiswa zvekushandisa.

ovhadhozi

Pokutanga inonzi gag dzepanguva kana dumbu yasukwa ane ovhadhozi zvinodhaka "Hydroxyzine". Mirayiridzo zvokushandisa anoudza kuti mune zvimwe zviitiko zvinokosha vachiongorora anokosha murwere, pakatanga yavaibvisa benzoate, caffeine, norepinephrine, uye kunyange ropa Sevamiririri, vakatakudzwa kubva ose matanho anodiwa kuti tirambe zvakakodzera nokushanda kwenhengo dzomuviri. Dzinenge mushonga ari mudziyo une, hemodialysis haaruramiswi.

Kakawanda, migumisiro ava reversible kana zviratidzo zvavo inonyangarika pashure zuva chipimo chemushonga kuti shanduro.

chipimo chemushonga

The mushonga chinotarisirwa nomuromo kana intramuscular jekiseni. The dose zvinobva nosologies, zera murwere uye chimiro umo zvinodhaka asunungurwa "Hydroxyzine".

Mirayiridzo dzokushandisa kunoratidza kuti symptomatic kurapwa kufunganya chirwere, mukuru akarumbidza yaunodya 25 kusvika 100 MG ari constituent fuma masikati. The anowanzodanwa kushandiswa chipimo chemushonga kuti 12,5 MG mangwanani uye dzimwe kwemasikati uye 25 - manheru.
In pauduku, preoperatively shandisa 1 MG chete makirogiramu kurema muviri pazuva manheru asati uye maminitsi 60 vasati nzira.

Nechinangwa premedication chinotarisirwa kuti vakuru 'Hydroxyzine "pane imwe dose pamusoro 50-200 MG zvinodhaka nomuromo kana muchimiro intramuscular majekiseni 1.5-2.5 MG pa makirogiramu nokushivirira uremu raitongwa awa rimwe asati kuvhiya.

Nechinangwa zvakazorodza kuvava zvinobudirira chipimo chemushonga kubva 25 kusvika 100 MG muna 3-4 yakakamurwa mishonga.

Children kubva gore 6 makore dose asingadi kupfuudza 1-2.5 MG pa makirogiramu kurema muviri pazuva mazvake mishonga.

Saizvozvowo dosing zvaiitwa vana pasi pemakore 6 makore itungamirirwe 1-2 MG chete makirogiramu kurema muviri masikati.

Maximum daily dose kuonekwa 300 MG. Maximum kuroorwa dose - 200 MG.

Vakwegura mharuro kurapa inokurudzirwa pa hafu chipimo chemushonga.

Chiropa uye itsvo kutadza zvinoda kururamiswa pamusoro chipimo chemushonga zvinodhaka "Hydroxyzine".

Guide anonyevera kuti kuzadzisa kunonyanyisa kuchirapa mugumisiro nokukurumidza mhinduro chinotarisirwa intramuscularly, yakadzika 50-100 MG paavhareji chete dose. It akakurudzira zvinodhaka Kutarisirwa mitoo kwemaawa 4-6.

In wepfungwa, mushonga rinoshandisirwa munhu chipimo chemushonga 300 MG kwemazuva. Ya kurapwa uyu 4 mavhiki.

Kana kuratidzwa nemishonga akadai muutera, hope, haagumiri mumazuva mashomanana, asi dose anofanira kuderedzwa.

matanho okudzivirira

Nepo pakatanga "Hydroxyzine" kubva "Adrenaline" yakareba zvishoma kunobudirira.

The mushonga ine muedzo zvainoita kunyaradza kunoita marwadzo analgesics series, doro, mapiritsi, barbiturates, nemishonga inoshandiswa nechinangwa zvinodhaka hypnotic uye zvimwe kuti inoodza mwoyo CNS basa.

Not varumbidzwa kwemajoini pokushandisa pfuma kana holinoblokatorami pamwe Mao FIs.

Kana pamwe zvokurarama kutora phenytoin anticonvulsant zvazviri zvinoderedza kubva negashiro yokupedzisira.

Chisingadiwi mawa pokushandisa zvinodhaka pamwe cholinesterase blockers.

A mhedzisiro kuwedzera plasma wevasungwa zvinodhaka dzingava chikumbiro dzaro FIs kuti chiropa makemikari.

Mawa kurapwa pamwe nevasori izvo tunodzivisa kushanda CNS, kana pamwe holinoblokatorami zvinoda chipimo chemushonga kuchinja.

With hanya huru inofanira ushandiswe varwere kuva propensity nokuda fibrillation kana kushandisa antiarrhythmics, uyewo avo varwere vari mavari convulsive kuratidzwa. The kurapa iri contraindication pakushandisa doro. Kana zvakakodzera, mufambiro bvunzo Kurwara kugamuchira "Hydroxyzine" kudzima kusvika 5 mazuva asati yakarongwa kuongorora. Kungwarira kunodiwa kana kushandisa zvinodhaka uye motokari kuzvidzora vatyairi kumwedzi uye varwere, ounyanzvi hwokugadzira kuti zvinoda yakakwirira yevasungwa.

Zvinofanira kurangarirwa kuti kushandisa injectables ndiyo chete ivepo intramuscular jekiseni. Subcutaneous jekiseni motokari kana kupinda neyokupedzisira mumidziyo guru kunogona kukuvadza tishu.

Zvipatara chokushandisa ichi kunogona vyzyvavt migumisiro venhema anobaya bvunzo.

Terms uye zvinhu zviri kushandiswa uye okuchengetera

Zvakakodzera muite kuvapo mushonga nokuda zvinodhaka "Hydroxyzine".

Mirayiridzo dzokushandisa rinoti mukanwa siyana mushonga havasi inochengeterwa anopfuura 5 years.

"Hydroxyzine". Testimonials

In vana, kushandisa mari pasi wokusagadzikana, akaderedza kutarisirwa span kunobatsira mwana kuti ave nechivimbo, pfungwa uye ndinzwe, anobvisa Zvinyamusi. Panguva iyoyo vari kurapwa zvinodhaka "Atarax" ( "Hydroxyzine") mirayiridzo kushandiswa anovimbisa kuti basa uye simba kuti mwana arambe chete. Marwadzo hadziwanzowaniki.

Maererano Mitsara varwere, nokushandisa dzimwe nguva "Hydroxyzine" (analogues zvinodhaka), zvinoreva kuti iye akadzikama uye chivimbo yakakura kupfuura zvimwe zvinodhaka zvakawanda. Vhunduka uye kushaya hope nefuma kunoita nani akotsira uye kurira hope. Zvisinei, nokubviswa zvinodhaka kwemazuva kuvhiringa muitiro akotsira, asi, pfungwa yokutanga shoma, migumisiro yokurapa chaizvo.

Mutengo zvinodhaka

Kutenga mushonga "Hydroxyzine" dzomuzana, sechikamu ine hydroxyzine, kungava chemishonga pamusoro mushonga. Price ndiyo 270-300 rubles por 25 mahwendefa 25 MG.

"Hydroxyzine". anoreva zvakafanana

Anoreva zvakafanana 'Hydroxyzine "ndiwo:" Hydroxyzine Canon "," Atarax "," Masmoram "," Ateraks "," Hydroxyzine "," Hydroxyzine Hydrochloride "," Alamon "," Duraks ".