The mushonga "Bekonaze": kurayira, analogs uye wongororo

Neutachiona kunokanganisa vanhu vazhinji. Kubvisa kuratidzwa dzakadaro, vanachiremba vanoti kushandisa chaiwo Anti-sema zvinodhaka, izvo yekudyidzana kuvandudza mamiriro murwere uye anobvisa zvinoitika zviratidzo.

Munyaya ino, tichakurukura nezvamai sei mishonga anoita zvakadai se "Bekonaze". kushandisa nzira iyi omunzvimbo mutungamiriri kuchaitawo kupiwa pazasi.

Release chimiro, akafanana, kavha

Kugadzirira "Bekonaze" mirayiridzo iri nested ari makadhibhokisi bhokisi, akaita muchimiro ane aqueous pfapfaidzo nokuda nasal kushanda. The kushingaira chezvinonhuwira ari mudziyo makabuda beclomethasone dipropionate.

Kutengeswa zvinodhaka yaipiwa muhombodo chaiwo dispenser.

Pharmacology mari vemo

Chii pfapfaidzo "Bekonaze", analogues iyo dziri pasi apa? medicament Uyu glucocorticoid kukamura uchishandisa intranasal fomu izvo ane Anti edema, Anti-anogumbura uye Anti-sema ehupfumi.

Details pamusoro ehupfumi zvinodhaka

Antiallergic zviito mushonga pasi kukurukurwa nokuda kukwanisa kwayo kutitadzise Kanotokonya susceptibility kuti zvoutachiona vanoshingaira zvinokuvadza (histamine, prostaglandins) uye nomuviri kuitika. Nemamwe mashoko, chishandiso ine yakananga paupenyu hwavo non-chaicho hyperresponsiveness.

Kugadzirira rinokurudzira chinovhiringidza pamusoro pedanda rechikepe muchitokisi degranulation, uye anobvisa zvose vanoshingaira anogumbura kuratidzwa sema hunhu. Rinotaurawo anodzosa kunhuhwidza. Ndicho ichi chinoratidza chinosiyanisa mishonga "Bekonaze" (pfapfaidzo) nedzimwe nzira pamusoro Kurwara.

Vaiona muiti anovandudza mucociliary chokufambisa uye haana chinomuwira neutrophils. Panyaya iyi, kuti mushonga haachinji masoja mukupindura noutachiona.

Anti-anogumbura ehupfumi kuti "Bekonaze" anotsanangura kushanda kwayo pane masero kubudikidza inonakidza receptors izvo mhosva transcription ane DNA chipfuro majini yokudzora kubatana kwetunhu mapuroteni mamorekuru zvinobatanidzwa anogumbura kwendangariro.

Maererano nezvokurara, vanoshingaira zvinodhaka anokwanisa tunodzivisa induction pamusoro nitric oxide usage, activation iyo ine raidudzwa aifarira-anogumbura anokonzerwa. Rinotaurawo kuchititadzisa kubatana kwetunhu aifarira-anogumbura cytokines vanotsamwisa kushoma.

Tinofanirawo kuziva kuti pashure kushandisa pfapfaidzo iri makavhara IgE kugadzirwa uye nokuumbwa leukotrienes ari mucous membranes. The medicament mwoyo chaizvo nebasa majini yokudzora kubatana kwetunhu makemikari nemamwe mapuroteni mamorekuru, izvo zvinobatanidzwa munyaya sema muitiro. Somugumisiro izvi zvinoderedza zvinyama edema uye kuderera mune secretion pakati omumuviri iri lining.

Pharmacokinetics zvinodhaka

kana mushonga wefodya, "Bekonaze"? Guide inoshuma kuti mushonga chose nokukurumidza woga kupinda nasal mucosa. About 5% of dose vakashandisa anopinda ropa. Kana gadziriro iri biotransformed zvizere panguva ndima yokutanga kuburikidza chiropa.

Very pasi bioavailability zvinodhaka kunoderedza mukana wokuti zvisingadiwi migumisiro kushoma kunyange pasi kushandiswa kwenguva refu.

The mushonga anosunga kuti sealbumin 80-90%. Its hafu-upenyu maawa 16. Medicament kubviswa nokuda itsvo, uye pamwe chete mutsvina yadzo.

umboo

Chinangwa waakaudzwa nasal Madonhwe "Bekonaze"? Maererano nezvokurara, mushonga inoshandiswa anogumbura pezvakaitwa noninfectious mavambo ayo anowanikwa mune nasal mhango. Uyewo rinoshandiswa kuti idzokororo nasal polyposis uye sema rhinitis (pamwaka kana gore rose).

Contraindications

Kana uchifanira kushandisa pfapfaidzo "Bekonaze"? Reviews vanachiremba kushuma kuti ichi zvinoreva pane kumbonyanya vakawanda contraindications. Hazvina varumbidzwa kushandisa kana asingashiviriri beclomethasone, uye mumamiriro ezvinhu akadai:

• yemaziso, myocardial infarction, renal zvokurwara hurongwa;
• amoebiasis, herpes meso;
• pulmonary tibhii, achangobva akatamisira uye kunotevera kuvhiyiwa pamusoro mhino;
• systemic fungal Zvirwere kana kwemabhakitiriya mavambo, hypothyroidism, ulceration pamusoro nasal septum;
• achiyamwa, pamuviri.

Drug "Bekonaze": okuti

mishonga Viewed iri ushandiswe chete intranasal kushandiswa. Ari chiremba zera boka kubva 6 makore uye vakuru chete mushonga inokurudzirwa kushandisa iri chete dose nerimwe hafu nasal mhango. Dzika instillation inofanira kuva zvitatu kana zvina kanomwe pazuva. Kana ukashandisa dose kaviri zvinodhaka, zviri jekiseni kaviri pazuva.

Sezvo tsika inoratidza kuti mishonga mugumisiro kwakacherechedzwa pashure kushanda pfapfaidzo mumazuva 5-7.

nemishonga

Drug "Bekonaze", mitengo iri pasi apa, zviri zvachose ngozi kuti vana vakura, kunyange kushandiswa kwenguva refu. yaivhuvhuta ake systemic akadaro zviduku.

Mune zvisingawanzoitiki zviitiko, mushonga anogona kukonzera zvisingadiwi omunharaunda siyana akadai sneezing, unopfuta uye kuoma iri nasal mucosa, uyewo ropa uye idzokororo herpes hweHIV. Mukuwedzera, muna zvisingawanzoitiki zviitiko, pane perforation pamusoro nasal septum.

In pamberi hypersensitivity murwere anogona kuratidza neutachiona zvakadai urticaria uye ganda rashes.

Mwaya "Bekonaze": dzomuzana uye mutengo

Kana zvakakodzera, mushonga "Bekonaze" inogona kutsiviwa dzakafanana nzira dzakadai se "Agistam", "Ekvazolin", "Otrivin" "Marimer", "Kamfomen", "Physiomer".

Kutenga mushonga "Bekonaze" iri muchimiro pfapfaidzo hakuzovi kwakaoma, sezvo wenyama zvinenge zvose Pharmacies pasina mushonga. Its ukoshi kunosiyana-siyana pakati 800-950 rubles.

Reviews kuti medicament

Testimonials pamusoro chipo Pfungwa kuti kukamura uchishandisa chikumbiro vari yakavhenganiswa chaizvo. Mumwe munhu anoti zviri zvikuru inobudirira kutsungirira basa uye anobvisa zviratidzo zvose sema rhinitis, uyewo kuzvimba ari nasal mhango vasiri rwarisa mavambo.

Zvisinei, pane chikamu nevanhu kushuma kuti zvinodhaka izvi zvachose maturo. Uyezve, vakawanda varwere chaizvo kunyara mari zvinodhaka. Kunyange zvazvo nyanzvi dzinoti mutengo wayo anonyatsokwanisa inopindirana yepamusoro.

The chete akanaka pfungwa chokushandisa ichi, izvo vanoti zviri zvachose varwere vose kuti kwazvo kazhinji kunokonzera nemishonga.