Monocytes ropa richinyanya sezvinoratidzwa Kuongorora

Tose nguva nenguva kusangana kujeka ezvokurapa. Sezvo CBC zvakaitika zvose, pane nguva dzose mubvunzo unomuka, chii monocytes, vangani vavo vanofanira kuva ropa, uye sezvinoratidzwa ukoshi vakawana kana monocytes ropa zvawanzwa?

Monocytes - yakakura pakukura masero matsvuku eropa, kuva mukirasi masero eropa machena. Maererano mamiriro - denderedzwa masero ane guru neerekitironi kushaya zviyo cytoplasm (agranulocytes) vanoteerera anogumbura pezvakaitwa mumuviri kuwedzera ropa ravo. A ezvinhu apo monocytes ropa vari yakakwirira, rinonzi monocytosis.

Masero aya achiumbwa mumwongo pamusoro monoblastov, pavanenge vakakamurwa meiosis, uye mazuva mashoma gare gare tama paropa kupinda munyama, uye ipapo pamukova cellular pamwero kuitawo phagocytosis. Kazhinji, izvi zviri kuchengetwa pakupindura kupinda ari chirwere apo monocytes vanova macrophages kare chokuita kuraramisa kutapata uye ichivharira wokumwe mapuroteni yokuumba antigen-antibody mubatanidzwa. In nedanho phagocytosis pamusoro monocytes hadzina kuparadzwa, sezvo zvinowanza eosinophils uye neutrophils, asi dzinoumba mugodhi kutsanangura nzvimbo chokutsva. A maitiro chinhu zvakafanana maitiro aya masero ari acidic runyararo.

Monocyte rine vakawanda lysosomes, izvo kugaya sero fagotsitiruemye zvinhu tichibvisa lesion nzvimbo uye kugadzirira kuti patsva. Vari kunyanya monocytes muropa, muri zvikuru aripo ari chirwatata, node nodes uye mumwongo saka zvinokuvadza mumwe wavo dzikira monocytes. Monocytosis kutaurwa nyanyisa namamota, zvirwere (njovhera, tiibhii), systemic zvirwere (lupus erythematosus, zvirwere ropa), collagenosis, granulomatosis.

Zviri izvi mononuclear leukocytes mune kuipa peripheral ropa - kwete kupfuura 0,03 - 1.00 × 109 / L, uye avo yaipedzerwa haafaniri kupfuudza 8-10% yose inowanwa leukocytes. Kana monocytes pamusoro ndozvakajairwa, ndiwo mukana kupfuura mimwe miedzo kuziva kunobva neutachiona uye akakodzera kurapwa. Monocytes vane cytotoxic nomugumisiro (tigume bundu masero uyewo zvirwere zvakadai semarariya), zvibereko basa yeimwe (IFN), zvinobatanidzwa munyaya kuziva dzimwe nevamiririri.

Kunyange kana monocytes ropa vachiwanda, hazvibviri nemazvo kurondedzera chokufenbera mufananidzo kushoma, kunobva chete avo quantitative zviratidzo. Nokuti chinangwa ichi isu vanofungidzira zvachose leukocyte yokuita ropa kana vakawanda monocytes, pamwe nokuwedzera kwenhamba lymphocytes uye, uye zvakafanana kuwanda eosinophils, asi kwakaderedza nhamba T-lymphocytes kugutsikana, rinogona aionekwa chikonzero yakanaka nei pathological ezvinhu. Kusiyana nehurumende apo monocytes ropa yakawedzera sezvo kuwanda neutrophil leukocyte kuchinja kuruboshwe, uye panguva imwe chete vasanyanye anoverengeka eosinophils uye T-lymphocytes.

Kana jeko kuderera kwenhamba monocytes iri kwakacherechedzwa muropa, ipapo totaura vagumirwe sezvo monocytopenia (monotsitopeniya). Mufananidzo uyu kuchengetwa muropa mwongo maronda, kana muitiro gemapoeza kutyora zviri generalized purulent zvirwere, hosha ropa, mishonga hormone, mupfungwa uye kuvhunduka ezvinhu, kuzvara uye nzira dzokuvhiya, uyewo akuvara zvitunha apo monocytes yakavakirwa. Munguva chiitiko nhamba monocytes mu peripheral ropa zvakafanira kuitisa bvunzo wechipiri ropa. On hwaro ichi, zvichava kupiwa kune runoenzanirana kunzwisisa mabatiro chaicho chirwere. Sezvo monocytes sei pamberi chirwere mumuviri, unogona anonyatsoziva kuti chikuru muupenyu achava asingaurayiwi kurapa ndinoiitawo symptomatic kurapwa.