Chirevo che "Diflucan" inzira ye "Fluconazole"

Izwi re "Diflucan" - rinoreva "Fluconazole" - iri mishonga inogadziriswa ine tsanangudzo yakanyanya. Iyo mishonga inokwanisa kubvisa basa rehuwandu hwemakemikari, kudzivirira kutendeuka ku ergosterol lanosterol. Mukuwedzera, mishonga inowedzera kuperevedzwa kwesero membrane, kudzivirira kudzokorora uye kukura kwezvirwere. Mushonga unobudirira muhutachiona hunofanirwa huchikonzerwa nefungi yejeri Candida, kusanganisira huwandu hwemhando dze candidiasis pamusana pekudzivirira muviri. Paunotorwa nemuromo, chirwere chacho chakanaka. Kubvisa muzinga kunotadzisa kudya kudya. Bioavailability yemishonga inenge 90%. Izvo zvikamu zvakawanda zveropa muropa zvinosvika 30-90 maminitsi. Mushonga wacho unoparadzirwa zvakanaka kumasukisi uye zvinodhaka, zvinopinda mumukaka. Zvinofanira kunzi kuti mutengo wechirwere "Fluconazole" wakaderera zvikuru kudarika "Diflucan" (yekupedzisira ichabhadhara kubva mazana mana kusvika masere mazana ruble).

Zviratidzo

Mushonga we "Fluconazole" (wakafananidzwa ne "Diflucan") unorayirirwa kuti cryptococcal meningitis, cryptococcosis uye dzimwe nzvimbo dzechirwere chekrisptococcal kune varwere vane zvirwere zvekudzivirira zvirwere uye zvirwere zvakasiyana-siyana zvekudzivirira muviri. Zviratidzo zvinosanganisira candidiasis generalized type, kuparidzirwa candidiasis, candidemia, mamwe marudzi ezvirwere zvinoparadza, causative agent iyo ndiyo fungus yeGenida. Chirwere ichi chinokurudzirwa kuti kudzivirirwa kwezvipembenene zvefungal kune varwere vane zviremara zvinotyisa. Anosarudza mushonga we mycosis wemakumbo, kugomera, trunk.

Dosing regimen

Iyo yakafanana ne "Diflucan" - chirwere "Fluconazole" - inorayirwa kune varwere vanobva kune makore gumi nemashanu vane masero anopfuura 50 kg. Nekrisptococcal zvirwere zvekusiyana kwemazuva nezuva rokutanga pane 400 mg. Zvadaro, muwandu wemishonga inoderedzwa kusvika 200 mg pazuva. Nguva yerapi yezvipatara izvi inobva mukubudirira kwehutano, iyo inotsigirwa nemigumisiro yeongororo yemagetsi . Kushandiswa kwe cryptococcal meningitis kunofanira kupedzisira kusati vhiki masere kusvika masere. Nekuparidzirwa candidiasis, chirwere chemakemia nemamwe zvirwere zve candidiasis zvechirwere chinopisa pazuva rekutanga, chiyero chemishonga iyi 400 mg, uye chirwere chacho chakaderedzwa kusvika 200 mg. Mukana wekushaya kukwana kwehutano hwehutano, muyero uwedzerwa kumashure ku 400 mg. Nguva yekurapa inobva mukubudirira kwegadziriro.

Side effect

Analog "Diflucan" - mishonga "Fluconazole" - inogona kukonzera mutsipa, kurwadziwa mumusoro, mimba, kurwadziwa mumimba, kupererwa kwechido, kuora mwoyo. Pamusoro pekurapa kunogona kukura thrombocytopenia, zvinokonzerwa nehutachiona muhupenyu hwedema yechiso, epidermal toxic necrolysis, kuchenesa kweganda. Nhoroondo yemapiritsi ingakonzera kukanganisa kwechiropa, hono, hypokalemia, hypertriglyceridemia.

Contraindications

Usaisa mishonga musati wasvika makore makumi mana, nekusawirirana kwezvikamu zvayo. Contraindicated pamwe chete kushandiswa nemishonga "Terfenadin", "Astemizol" uye vamwe, zvichipa kuenderera mberi kweEvt-interval. Kuchenjerera munguva yekurapa kunoratidzirwa nechisarudzo chezvirwere zvakasiyana-siyana (kune kukanganisa kwema electrolyte balance, zvirwere zvepfungwa dzehupenyu nevamwe).