"Agapurin": mirayiridzo kushandiswa, zvechokwadi

Chii chinodhaka "Agapurin"? Mirayiridzo kushandiswa, kusunungurwa chimiro uye Kuronga mari zvichakurukurwa zvishoma mberi. Uyezve, munyaya ino uchadzidza pamusoro nyaya iri iyo zvinodhaka riri basa kana kushandiswa kwayo iri zvachose wairambidza, kana ane marwadzo uye zvichingodaro.

Murwiyo uye chimiro zvinodhaka

Pane zita renyika mu "Agapurin" chinodhaka? "Pentoxifylline" - iri zita rake wechipiri.

Pari mushonga inowanika zviviri zvakasiyana siyana:

1. Biconvex mahwendefa zvemapuranga (chena) uye kuva vaima chivheneke. chinodhaka ichi rine basa zvinoriumba ndiye pentoxifylline uye mamwe zvinhu (lactose monohydrate, chibage starch, colloidal anhydrous silica, talc uye magnesium stearate). Panyaya goko, chinosanganisira zvinhu zvakadai carmellose yavaibvisa, crystalline sucrose, weupfu sucrose, talc, methylparaben, titanium dioxide, silica colloidal anhydrous uye nomuti.
2. Solution (zvakajeka, Hauoneki) kuti jekiseni. medicament Izvi zvinosanganisira pentoxifylline, yavaibvisa chloride uye mvura kuti jekiseni.

Ini ndingadawo kutaura chokwadi kuti kwakadaro zvinodhaka analogue anogona kuwanikwa chemishonga necheni se "Agapurin kutadzisa". Instruction zvinodhaka rinoti ndiye mumiririri kwenguva refu chiito. Inowanika pamahwendefa, izvo zvinenge zvakazara firimu unhani. mishonga iyi ine pentoxifylline uye mamwe zvinhu zvakadai hypromellose, povidone, talc, uye magnesium stearate.

pharmacological ehupfumi

Chii chinodhaka "Agapurin"? Mirayiridzo Use inotaura kuti mumiririri uyu antispasmodic uye ndowenyika purine boka. It yekudyidzana kunonatsiridza kuparadzirwa ropa, uyewo yaro rheological ehupfumi. The uchishandisa nhungamiro akati medicament kuna phosphodiesterase chinovhiringidza, uye kuwedzera zviri ATP mu erythrocytes uye musasa maplatelet pamwe bara saturation simba nekugona. Izvi zvinoguma vasodilation richikwidibira zvachose vascular nemishonga (peripheral), uye miniti uye kuwedzera ronda vhoriyamu pasina kuchinja zvikuru mwoyo yevanhu.

The mashandiro kuita zvinodhaka

Chii mashandiro chiito "Agapurin" chinodhaka? Mirayiridzo dzokushandisa achipa mukana dzoga mhinduro yomubvunzo uyu. Pashure tikashandisa medicament dilate coronary arteries, uye ipapo kuwedzera okisijeni hurukuro kune pulmonary midziyo uye myocardium, hazvina antianginal kushanda uye kunonatsiridza oxygenation ropa.

Zvinofanira kucherechedzwa kuti akauya Pfungwa anokwanisa kuwedzera mataurire kufema musculature, kunyanya pamusoro diaphragm uye intercostal tsandanyama.

Kana intravenous jekiseni inotungamirira vawedzere rubatso kuparadzirwa, uyewo kuwedzera inzwi ropa ruchiyerera napakati 1-tsu-chikamu. Uyezve, mushonga uyu zvinokonzera kuwedzera zviri adenosine muuropi uye ane kwaibatsira pamusoro bioelectrical basa tsinga.

Maererano murayiridzo, akati medicament anokwanisa kuderedza viscosity ropa, kuwedzera elasticity pamusoro erythrocyte Kamudzira uye kuvandudza microcirculation pamwe havachanyatsogoni kutenderera.

Zvii rine mushonga "Agapurin"? Mirayiridzo zvokushandisa rinoti muna arterial occlusive chirwere (peripheral) rinoita zvinodhaka kungaita kuti kubviswa usiku chinyamunhari chinorwadza vari mhuru, asi elongation daro kufamba uye marwadzo pa zororo.

Pharmacokinetics

Medicine "Agapurin" iri kukurumidza rinoita mune chiropa. Izvi unobereka zvinoshingaira metabolites. wevasungwa dzavo muropa kanoverengeka kupfuura wevasungwa anokosha fuma.

Matafura vakapa medicament sezvo metabolites mu uwandu 94%, uye zvasara - kubudikidza ura. Mumwedzi wokutanga 4 maawa pashure ingestion zvinodhaka kusunungurwa imwe mari 90% of dosages kushandiswa. In imwe unmodified chimiro, zvinonzi unoratidzwa nenzira Vhoriyamu 2%. Zvinofanira kucherechedzwa kuti yezviri nefuma uye metabolites ose pentoxifylline asingadi kusungira kuti ropa mapurotini.

Kana vakadhakwa itsvo basa decelerates goho metabolites. Kana chiropa basa abnormalities vakachengeta dzikawedzerwa hafu-upenyu, uye kwakawedzera bioavailability.

Drug "Agapurin" (Mahwendefa): mirayiridzo kushandiswa

Maererano dzakabatanidzwa mirayiridzo yacho medicament, inofanira kutorwa chete uye panguva imwe chete zuva pashure kudya zvokudya, mvura yokunwa pachena. The mushonga uri kuzvidzosera zvisingaiti kutsenga.

Initial chipimo chemushonga zvinodhaka riri 200 MG katatu pazuva. Kana murwere kuva refu kurapwa kana akanga murombo kubvumirawo zvimwe zvinodhaka, ipapo chete dose inogona kuderedzwa chaizvo kaviri, asi chengeta uwandu yemichato.

Zvinoreva chipimo chemushonga daily haafaniri kupfuudza 1200 MG.

Zvino munoziva kuti kushandisa zvinodhaka "Agapurin" (Mahwendefa). zvakafanana nzira application mirayiridzo yose kusunungurwa rine mashoko pamusoro chete dosages. Zvisinei, kana kushandisa kuti tikwanise kuderedza multiplicity kugamuchirwa.

Mirayiridzo kushandiswa kuitwa jekiseni

Sei kushandisa zvinodhaka "Agapurin"? Mahwendefa vari ushandiswe kakawanda kupfuura injectable mhinduro. Kana paine chikonzero chinoita murwere haagoni mushonga nemumuromo, iye ndishandise majekiseni.

gadziriro iyi kutengeswa mhinduro muchimiro kuti jekiseni anogona kutarisirwa nomumwe anotevera nzira:

1. IV. Zviri ampoule zvinofanira rakasanganiswa muna 5% shuga mhinduro kana muna 250-500 Rine mamiririta chloride (0,9%) yavaibvisa chloride. The mushonga anofanira kuzviita zvishoma nezvishoma, kwete Rine mamiririta anopfuura 150 paawa. Kana murwere inobvumira mushonga, nezuva dose kubvumirwa kuwedzera kusvika ampoules maviri, kureva 200 MG.
2. Intramuscularly. The mushonga chinotarisirwa pa 100 MG kaviri pazuva. Hazvina sanganisa zviri chinu.
3. Intraarterially. Treatment murwere vanofanira kutanga kwokubatsira rimwe ampoule, izvo zvinofanira kwerubwinyo rwakagara rwuripo rakasanganiswa muna 20-50 ml isotonic yavaibvisa chloride mhinduro. Kana uchida kwenguva refu kurapa, kuti dose anogona ngazviwedzerwe 2-3 ampoules. Vanofanira rakasanganiswa kusvika 30-50 Rine mamiririta.

Zvinofanira kucherechedzwa kuti optimum huwandu medicament akurukurwa kunotemwa chete nachiremba, uye chete mukufamba murwere zano munhu.

Medicament "Agapurin": zvairatidza yokushandisa

Asati kushandisa mushonga uyu, iwe unofanira bvunza chiremba wako uye kuti kuedzwa. Pashure pezvose, mushonga basa chete pasi dzimwe zvarakasiya. The Pamazita tichakurukura zvimwe.

1. Trophic kusagadzikana munyama kuti akabuda kuzorwa colour varombo venous kana arterial microcirculation (akadai neronda rinonyenga, varicose maronda, frostbite, uye zvichingodaro.).
2. Kweropa zvirwere (peripheral) riri kuumbwa somugumisiro anogumbura, atherosclerotic uye shuga kwendangariro. mishonga sezvakarayirwa kuti "inoratidza" claudication, izvo zviri kukonzerwa atherosclerosis, arterial occlusive chirwere, uye shuga angiopathy.
3. Chirwere uye chenjera ischemic ronda, inova ischemic mavambo. Uyewo, kuti mushonga inoshandiswa chepfungwa arteriosclerosis, paresthesia, angioneyropatii, Raynaud nehosha uye akrozianoz.
4. Havachanyatsogoni kuparadzirwa munzvimbo nhumbi ziso nadzo (chakasimba uye chisingaperi kweropa kukundikana, vascular uye pajira riya membranes Meso).
5. State yomuka pashure ischemic kana Hemorrhagic sitiroko.
6. Kusagadzikana pakati nzeve vascular mavambo, ayo achiperekedzwa kunzwa kurasikirwa.

Contraindications pakushandisa

Kana usingagoni kushandisa mishonga "Agapurin"? Kushandiswa kwezvinodhaka ichi hakubvumidzwi pasi zvinotevera ezvinhu uye zvarakasiya:

• chenjera myocardial infarction;
• akaratidza coronary kana chepfungwa arteriosclerosis;
• akaratidza kukanganisa mwoyo mutinhimira;
• porphyria;
• kusingadzoreki arterial hypotension;
• wandisa ropa;
• chenjera Hemorrhagic Kurohwa;
• retinal ropa;
• pamuviri, uchiyamwisa;
• makore 18 (kuchengeteka uye efficacy vasina dzakatangwa);
• hypersensitivity kuti pentoxifylline, uye zvinhu kubva muboka xanthine nomukaka.

Vakangwarira kushandiswa mishonga

With kutarisira mukuru chishandiso kuiswa varwere vane tsika arterial hypotension, labile BP, mwoyo kutadza (chirwere), tsika ropa, renal uye hepatic insufficiency, uyewo mamiriro pashure pakuvhiya.

nemishonga

Pane divi migumisiro kubva zvinodhaka, "Agapurin"? Mahwendefa gwaro iro kukurukurwa kumusoro, uyewo mhinduro jekiseni kungaita zvinoverengeka migumisiro yakaipa. Ngationgororei navo zvizere.

• Zvomudumbu maitiro: cholestatic chiropa, intestinal atony, kusemburwa cholecystitis, muromo yakaoma uye kurasikirwa kudya.
• Tsinga: kufunganya, kushaya hope, dzungu, chinyamunhari chinorwadza uye nomusoro.
• tsinga uye ganda: kuzvimba, pfava zvipikiri, chiso Flushing, Flushing pamusoro chipfuva uye chiso.
• Kumwoyo: arrhythmia, venhema angina, mberi angina pectoris, tachycardia uye vakaderera BP.
• Miviri hematopoiesis uye hemostasis gadziriro: thrombocytopenia, leukopenia, pancytopenia, gipofibrinogenemia kubva intestinal ropa, dumbu, subcutaneous capillaries uye mucous membranes.
• Kutsinga dzinouya nhengo: vasingadzoreki chiratidzo uye scotoma.
• Neutachiona: pruritus, urticaria, angioedema , uye anaphylaxis.

zviitiko ovhadhozi

Chii chinoitika kana ukashandisa yakakwirira mishonga mushonga "Agapurin" (400 MG, 600 MG, 1200 MG)? Panyaya iyi, murwere anogona kuona pathological zviratidzo zvakadai muutera, kwakaratidzwa zvinoderedza BP, dzungu, tachycardia, syncope, somnolence, generalized tonic-clonic nezvipusha, kurasikirwa pfungwa, hyperthermia, kushatirwa, gastrointestinal ropa zviratidzo (semuenzaniso, kurutsa " kofi nhandare ") uye areflexia.

Muchiitiko ichi zvinoda kukurumidzirwa symptomatic kurapwa riri kutaurirwa kuramba kuipa BP uye kufema ushande.

Mirayiridzo kushandiswa kwezvinodhaka

Zvaunofanira kuziva usati kushandisa zvinodhaka "Agapurin"? Reviews vanachiremba vanoti mushonga wakanaka panguva basa iri, asi mishonga vanofanira pasi pakuomerera kudzora BP. Muchiitiko chino, zviri varwere mwoyo nokukundikana (chirwere) chinodiwa kuzadzisa muripo kutenderera.

Zvinofanira kucherechedzwa kuti varwere chirwere kuti "chirwere cheshuga" kushandisa zvinodhaka hypoglycemic, kushandisa mumiririri uyu guru mishonga kunokonzera raidudzwa yomuropa. Naizvozvo dose kugadziridza zvakakodzera kwavari.

Tiine mawa kushandiswa kwezvinodhaka pamwe anticoagulants vanofanira kunyatsoongorora kuongorora mamiriro ropa coagulation hurongwa.

In varwere vanenge vachangobva oparesheni, unofanira kugara kuongorora wevasungwa kuti Chizenga uye hematocrit.

The raitongwa chipimo chemushonga inofanira kuderedzwa pavarwere vane kusagadzikana kana yakaderera BP.

Vanhu vakura vanogona kuva dose duku.

Maererano zvidzidzo, kuputa yekudyidzana akazoita kuchirapa efficacy zvinodhaka.

pentoxifylline kugarisana nevamwe aizomupa mhinduro zvinofanira kuongororwa mukati nomumwe nyaya imwe neimwe.

Kudyidzana nedzimwe nzira

The rinoita fuma pentoxifylline kazhinji runogonesa kuitwa nevasori kuti chokuita kweropa. mishonga yakadaro zvinosanganisira zvakananga uye zvisina kunanga anticoagulants, valproic acid, thrombolytics, uye anitibiotiki (semuenzaniso, zvinodhaka "Tsefamandol", "Cefoperazone", "tsefotetan").

Akati mumiririri kunowedzera kubudirira nomumukanwa hypoglycemic uye zvinodhaka antihypertensive, uyewo jekiseni.

Hatigoni kutaura kuti zvinodhaka "cimetidine" Sezvineiwo kunowedzera wevasungwa kuti pentoxifylline muropa. Izvi zvinowedzera mukana nemishonga.

Co-kutarisira "Agapurin" chinodhaka, wongororo zvakatuswa pasi apa, nevamwe xanthines kunotungamirira kunyanyisa huta anzwe.

Nzira dzekufambisa gadziriro kuchengetwa, wongororo payo, mutengo

Drug "Agapurin" anotengeswa munyika dzinenge dzose chezvinodhaka. Buy Mahwendefa 60 (100 MG), iwe Podràs avhareji pfuurei 250 rubles Russian.

Testimonials ose medicament uyu zvakanaka. Ndokusaka kazhinji dzimwe zvinodhaka ushandiswe varwere vane matambudziko nemidziyo ropa.

Zvinofanira kucherechedzwa kuti kumbonyanya guru dzakakurumbira mushonga "Agapurin" iri mukusimbisa muviri. Reviews muviri vanoti chokushandisa ichi zvinofanira kufungwa aparadzane zvimwe zvinodhaka kuti kuvandudza ropa riyerere. Pamusoro pazvo, ndiro inonyatsobudirira uye asi chipa.

Active medicament riri kutora nevatambi, sezvazvakanyorwa anogadzirwa kwete chete muchimiro ane injectable mhinduro, asi piritsi fomu. Pharmacies chokushandisa ichi chinogona kuwanika pasi mamwe mazita kuti unorira "Pentoxifylline" kana "Trental".

Huru basa raimiririra zvinodhaka mabasa zvakawedzera Matauriro midziyo ropa, nokuderedza ropa viscosity uye kuwedzera ropa riyerere. Zvose izvi iguru nzira kuita kupomba kudzidzisa mitambo, kana pane kunzwa simba kushanda tsandanyama kupomba.

Shandisa mishonga iyi ruzivo muviri vanofanira kungwarira zvikuru, nokuti kunogona kukonzera nyore imwe ovhadhozi uye zvinoverengeka nemishonga.

Ramba "Agapurin" kudiwa mune rima, nzvimbo yakaoma pasina mukana kuvana vaduku. Nokudaro kuchengetwa tembiricha zvinodhaka riri madhigirii 10-15 chete. Ichiri kushanda hwakaratidza pamusoro kavha uye makore maviri. Shure iyi, kushandiswa kwezvinodhaka hakubvumidzwi.

In mhedziso, tinoona kamwe zvakare kuti hatifaniri kuva kuzvipira kugadza pachavo kutora mushonga uyu. Duration kurapwa uye chipimo chemushonga tinofanira kutsunga nachiremba kuti imwe murwere.