The mushonga "Acyclovir-Akos" (Mahwendefa). Mirayiridzo dzokushandisa vana uye vakuru, wongororo

Mune dose kurapwa waakaudzwa, "Acyclovir-agos"? Mirayiridzo kushandisa mapiritsi aya anoratidzwa pazasi. Uyewo, uchadzidza sei kushandisa nzira iyi, kana vane chero divi migumisiro contraindications, Rinowanikwawo ayo akafanana, uye chii pasuru ruchapinda pasero.

Zvinoumba, description, zvinodhaka kavha

Ndezvipi zvinoriumba rine "Acyclovir-agos" (Mahwendefa)? Mirayiridzo Dzokushandisa inoti yezviri chezvinonhuwira kuti zvinodhaka ndiko acyclovir. Uyewo unotora uye mamwe zvokubikisa sezvo talc, magnesium stearate, uye mbatatisi starch.

"Acyclovir-agos" - Mahwendefa (murwere inofambiswa zvichabviswa kurondedzerwa pashure) Valium jena Valium uye chinhu. In yavakatengesa zvinodhaka anopinda gandiwa masero kuti inoiswa atorwa. Uyewo, mushonga uyu anogonawo kuwanika pemahombekombe rima rinoonekera.

The pharmacological ehupfumi zvinodhaka

Sei "Acyclovir-agos" (Mahwendefa)? Mirayiridzo Use rinoti kuti antiherpetic antiviral mumiririri. mushonga uyu chakaita zvokugadzirwa purine nucleoside analogue. Anokwanisa tunodzivisa nemavhairasi kuberekana kubva herpes simplex, cytomegalovirus, uye Epstein-Barr utachiona uye Varicella zoster.

Features mishonga

Maererano nenyanzvi, "Acyclovir-agos", wongororo zvacho zvakanaka kune mukuru zvakadini, zvinoratidza basa rakanaka pamusoro nemavhairasi anokonzera herpes zoster, uye chibhokisi.

Pamusoro pokugamuchira medicament kupinda utachiona masero phosphorylation kunotanga. Acyclovir iri dzikwanise acyclovir monophosphate. Pasi pokudzora vokupedzisira guanylate cyclase iri mudzoke kunyika diphosphate izvo, akavapindurawo, iri vatendeukira kuna triphosphate.

The mugumisiro vanosarudza zvinodhaka riri utachiwana, uyewo ayo pasi toxicity kuti muviri nokuti kuti chacho vanoshingaira chirungiso haisi substrate nokuda enzayemu thymidine kinase. Panyaya iyi, hazvina chepfu muzvitokisi mammalian.

Pashure kutendeuka kuti acyclovir acyclovir triphosphate izvozvo kunoita kuti kurwadziwa kuve kwetunhu nemavhairasi DNA 3 zvigadziriswe:

• unotsiva deoxyguanosine triphosphate;
• revatema kupinda DNA cheni, uye ipapo inoguma elongation kwayo;
• munhu mwoyo chaizvo muDNA herpes simplex nezvakadaro.

Somugumisiro dzokuteerera kwakadai chinomisa utachiona kubva replicating.

acyclovir kunyatsoshanda zvakare nokuda kuwanda kwayo ari mumasero kuti kare nechirwere utachiona. Herpes mushonga kunodzivisa nokuumbwa maronda itsva, uye kunoita maronda, kunoderedza marwadzo uye ane immunostimulating nomugumisiro.

Pharmacokinetic parameters antiherpetic mahwendefa

Apo Absorção de Água kunoitika "Acyclovir-agos" chinodhaka? Mirayiridzo dzokushandisa inoshuma kuti pashure nomumukanwa Kutarisirwa chiri chiduku wefodya kubva ura. In ichi fomu wevasungwa kwakadaro (dose-zvaanoda), izvo chaizvo kwakakwanira zvinobudirira kurapa nokuda nemavhairasi zvirwere.

Food ane zvinenge hapana zvainoita Absorção de Água yezviri fuma. With kuwedzera mishonga yacho bioavailability zvinodhaka kunodzikira.

The kunonyanyisa wevasungwa zvinodhaka nemarudzi kuenda mukati mune imwe mari 200 MG 5 nguva pazuva iri 0.75 g / Rine mamiririta, uye shoma - 0.45 g / Rine mamiririta. Uhu huwandu vanoti papera maawa maviri.

Yeplasma vanoshingaira chirungiso anosunga kuna 10-35%. Panoparadzana mwoyo ropa-uropi mhinganidzo, uyewo anenge munyama zvose uye nhengo (nemapapu, uropi, lacrimal fluid itsvo, ura, chiropa, tsandanyama, aqueous zvinosetsa, mukaka, urume, chirwatata, Líquido fluid dumbu, muchivande uye mucous membranes ari nyinyo, uyewo zviri herpetic vesicles).

Drug muviri ari chiropa. Izvi unoumba metabolite 9-inonzi karboksimetoksimetilguaninom.

Akaratidza medicament kuburikidza itsvo (62-91% of dose) uye kuburikidza zvomudumbu turakiti. Uyewo kuronda uwandu mushonga takatsunga uye patinofemera kunze pedyo murwere.

Kana muchigamuchira mushonga mukati yaro hafu-upenyu (mu vakuru) ndiyo - maawa 3,4, uye vana (makore 1-18) - maawa 2,4. Saka, zvakanaka kuti kuziva kuti mwero excretion zvinodhaka DZEMUNHU DZINODZORA nezera.

zvairatidza medicament

Kana achiita "Acyclovir-agos"? Kushandiswa kwezvinodhaka izvi zvinoratidzwa kuti kudzivirirwa uye kurapwa kutapukirwa zvinokonzerwa nemavhairasi Varicella zoster uye kupisa nokuvava simplex (nezvemarudzi 1 uye 2). Saka, mushonga uyu zvinobudirira anobata:

• herpes simplex ganda uye mucous membranes (zvepuraimari uye idzokororo);
• herpes zoster;
• yokubereka herpes (zvepuraimari uye idzokororo);
• herpes zoster;
• varicella (zuva rokutanga pashure mapundu anooneka).

Zvinofanira kucherechedzwa kuti basa zvinodhaka riri ushandiswe varwere vane zvikuru immunodeficiency (semuenzaniso,-neHIV vanhu, ndinobvisa uye vachitsigira immunosuppressive mishonga).

Contraindications

Mune zvimwe zviitiko, akarambidza kushandisa "Acyclovir-agos" (Mahwendefa)? Tungamirira pfungwa inotevera contraindications:

• chevana zera (makore anosvika matatu);
• hypersensitivity kune basa fuma, uye chokuita valacyclovir.

Nokungwarira akaipisisa, mushonga uyu ushandiswe panguva pamuviri, renal kukundikana uye kupera muviri, uyewo paanenge achiyamwa.

Drug "Acyclovir-agos": sei kuti vakuru?

Mahwendefa zvinofanira kutorwa zvokunwiwa, pasina pamusoro zvokudya girazi bani mvura.

Vakuru nokuti dambudziko herpes simplex utachiona muna mucous membranes uye ganda ushandiswe MG 200 zvinodhaka kashanu pazuva. Tora mushonga inofanira ose maawa mana (kunze akarara).

Kazhinji, nguva yokurapa pakugadzirira uyu mazuva mashanu. Asi kana zvakakodzera, anogona kuvandudzwa (maererano yachiremba audzwa).

Mukurapa vanhu vane immunodeficiency chete chipimo chemushonga kurapwa yakanga yawedzera kusvika 400 MG, uye nguva yose kosi - kusvika mazuva gumi uye zvakawanda.

Varwere Adult vane nhengo dzokubereka herpes inokurudzirwa kutora mushonga pa 200 MG kashanu daily (maawa mana ose) kwemazuva 10 (kana zvichidiwa mushonga inogona kuwedzerwa). Treatment vanofanira kutanga nekukurumidza mushure panowanikwa zviratidzo chirwere rokutanga. Kana pane zvazvo, mushonga wacho ushandiswe kare muna prodromal munguva.

Kuti adzivise dzokororo kutapukirwa kuti anokonzerwa herpes simplex utachiona, mishonga waakaudzwa 200 MG kanomwe pazuva mana (maawa matanhatu ose). Vanhu vane kwomuzvarirwo kutapata anogona kushandisa mushonga mune mari 400 MG kaviri pazuva (ose maawa 12). Kana akaratidza immunodeficiency chipimo chemushonga inoramba yakafanana, asi kakawanda ichiwedzerwa kusvikira kashanu pazuva.

Idzokororo yokubereka herpes (kanenge katanhatu pagore) anofanira kutevedza inotevera zvaiitwa: 200 MG kashanu pazuva kwemazuva mashanu. Kana Zvikamu inodzokororwa nguva anopfuura matanhatu gore, murwere ushandiswe 400 MG zvinodhaka kaviri pazuva kwemwedzi 12. Ya prophylaxis inowanzopiwa pakutsvaga ya nezvenguva apo pane mukana wokutapukirwa.

Pakurapa herpes zoster kana zoster murwere raitongwa 800 MG zvinodhaka kashanu pazuva (maawa mana ose) kwemazuva 7-10.

Kufadza kuroorwa dose zvinodhaka riri 800 MG.

Vanhu vachitora yepamusoro mishonga zvinodhaka vanofanira kugamuchira yakawanda emura.

"Acyclovir-agos" (Mahwendefa): kudzidziswa vana

Vacheche, ane zera yasvika makore matatu, kuti mushonga anofanira kuzviita chete ruzivo pediatricians. Kazhinji, chipimo chemushonga kwavari zvakafanana chipimo chemushonga nevakura.

Nokuti Mabatirwo chibhokisi vana vanopfuura makore matanhatu kupa 800 MG zvinodhaka kanokwana pazuva, uye mwana makore 3-6 Makore - 400 MG mana kanomwe pazuva. Nokuti kunyatsoenderana dosing vanachiremba kushandisa mutoo: 20 MG paminiti makirogiramu muviri uremu mwana. Tora medicament anopfuura 800 MG mana kanomwe pazuva hakubvumidzwi.

Duration yokurapa muvarwere vaduku mazuva mashanu.

In vanhu vane havachanyatsogoni itsvo nerevane Anodei dose kugadziriswa, ukuwo kugamuchirwa maitikiro. It kunobva mhando chirwere uye zvinokosheswa creatinine Clearance.

Nemigumisiro pashure ingestion mahwendefa

Medicament "Acyclovir-agos" zvikuru kazhinji kunokonzera nemishonga. Asi, maererano nemirayiridzo, vachiri nzvimbo kuva.

1. Kuda kurutsa, vakawedzera bilirubin zviratidzo, manyoka, abdominal marwadzo, kurutsa, reversible kuwedzera chiropa makemikari.
2. Chenjera renal kukundikana, yakakwirira serum creatinine yomuropa muropa uye urea.
3. Leukopenia, kupererwa neropa, thrombocytopenia.
4. Headache, aone zvinhu zvisipo, chetsinga zvirwere, reversible, kuvhiringidzika, dzungu, paresthesia, hope, pakoma, nokugwinha.
5. Rashes, dyspnoea, photosensitivity, angioedema, mapundu, fivha, pruritus, lymphadenopathy, anaphylaxis, nokusagadzikana, madzerere, peripheral edema, myalgia.
6. Kuneta, alopecia.

Zvinofanira kucherechedzwa kuti vanhu vanogamuchira zvinodhaka yemaARV, mamwe yaunodya mishonga "Acyclovir-agos" haakonzeri kuwedzera chepfu migumisiro.

Dzinenge kurumbidza pakushandisa mari antiherpetic

Zvaunofanira kuziva asati atora "Acyclovir-agos" (Mahwendefa)? Instruction inoti kuti kwenguva refu kana kudzokororwa kurapa vanhu vane akaderedzwa zvirwere chinzvimbo kungaita kuti paumbwe utachiona utachiona basa rayo chiito.

Clinical chengetedzo zveBhaibheri kushandisa zvinodhaka ichi panguva pamuviri asina. Panyaya iyi, kushandisa zvinodhaka "Acyclovir-agos" unoratidzwa chete kana kubatsira kungaita kuti amai zvikuru kupfuura zvingakanganisa azvarwa.

In kurapwa mukuru dzaiita dosages murwere vanofanira kunwa zvakakwana kwazvo mvura.

Panguva pamukaka mushonga basa chete Muzviitiko, pfupi kosi. Izvi imhaka yokuti mushonga riri shoma kupinda zamu mukaka.

Medicament "Acyclovir-agos" hakuiti uzvidzivirire pabonde herpes. Panyaya iyi, panguva kurapwa, murwere haafaniri zvepabonde.

Reviews wevarwere pamusoro mishonga

Zvino munoziva sei uye nei kuti taurira mushonga "Acyclovir-agos". mirayiridzo kushandiswa muperekedzi nzira akarondedzerwa zvizere kumusoro.

Maererano inofambiswa ruzhinji varwere kushuma mushonga zvinobudirira kunooneka pacharo pachando maronda. Kana iwe utore piritsi pakarepo mushure Detective zviratidzo herpes rokutanga, murwere apore achava zvikuru nokukurumidza.

Zvinofanira kucherechedzwa kuti "Acyclovir-agos" zvinobudirira anobata shingles uye chibhokisi.

Kuwedzera kurapa, mushonga inowanzoshandiswa kuzvidzivirira nechiyero. unyanzvi hwake rworudyi anobatsira kuderedza uwandu zvazvo kushoma.

Mutengo zvinodhaka

Zvinofanira akati mukuwedzera padunhu kunyatsoshanda zvinodhaka "Acyclovir-agos" Varwere anofara uye avo vachiri pasi mutengo. Buy Mahwendefa 20 antiherpetic zvaunogona kuti 30-40 rubles Russian. The wainyatsotaura yakawandisa zvakakwana nokuda yawapiwa.

Sezvineiwo, ndiye ane mari yakaderera uye analogues zvinodhaka.