Prodrug "Parnavel": mirayiridzo kushandiswa

Kugadzirira "Parnavel" mirayiridzo Chinyorwa rinotsanangura somunhu prodrug, inova munhu ACE inhibitor uye ane mucherechedzo antihypertensive kushanda. Kushanda chokushandisa ichi ndicho kukwikwidzana chinovhiringidza pamusoro ACE basa, vakabva zvichitungamirira vasanyanye wevasungwa pamusoro angiotensin II. Nokutanga mishonga "Parnavel" (mirayiridzo kushandiswa izvozvo zvinoratidza) akaderedza preload, afterload (OPSS), uye kurwisa iri pulmonary mumidziyo ropa, uye inowedzera kunetseka shiviriro. Pamusoro pharmacokinetic ehupfumi ose nevasori, ipapo vakaratidza kunotangira akacherekedza hypotensive chaizvoizvo munguva makumi matanhatu maminitsi pashure nehurumende wokutanga, richisvika kunonyanyisa ayo pashure maawa mana kana masere uye vairamba yose zuva.

Available mushonga "Parnavel", mitengo yakanga zvichisiyana maviri namakumi mashanu rubles mazana matatu, ari muchimiro kwakajairika kumativi mapiritsi. The Zvinoumba rimwe piritsi sezvo huru vanoshingaira chinhu kunobatanidzwa mukati kutsanangurwa perindopril erbumine milligrams mana.

Tora mushonga "Parnavel" mirayiridzo Chinyorwa anokurudzira kuti chinangwa chokungorwadzisa pakurapa chirwere siyana mwoyo nokukundikana kana BP. The kutanga dose zvinodhaka, kazhinji pakati mumwe uye milligrams maviri pazuva panguva, uye kugadzira - vaviri vana milligrams pazuva.

Use Hwendefa "Parnavel" nyanzvi dzinokurudzira zvakasimba kuti vanhu vane nomumwe kusada perindopril erbumine uyewo vose vaya vane kubatwa kuti kukura angioedema. Mukuwedzera, ndandanda yakananga contraindications pakushandisa zvinosanganisira pamuviri uye makore gumi nemasere. The lactation nguva zvakafanana haafaniri kutora zvinodhaka "Parnavel". Mirayiridzo yokushandisa Notes uye undesirability kushandiswa kwayo kune BP yakakwirira kana kusimbiswa renal kukundikana. Vanhu kutambura kubva dhefisiti ine mvura uye yavaibvisa, vasati vatanga nzira yokurapa kunofanira fanira kuita Yaunoti kutsiurwa nemvura electrolyte kusaenzana.

Uyezve, unofanira kunyatsofunga chaizvo kushandisa piritsi "Parnavel" panguva imwe chete mishonga anogona kukonzera kuwedzera padanho potassium.

Mukugumisa, zvinofanira akati pamusoro zvichibvira nenjodzi kuti anogona kukonzerwa nokutora chinodhaka ichi. Somuenzaniso, nyanzvi dzinoti pane kumbonyanya yakakwirira pangozi akaoma chikosoro, nomusoro, dzungu, nenyonganiso kuravidza uye muromo yakaoma. Uyezve, kungava kakawanda rokuchinja mwoyo, pabonde dysfunction, ganda mapundu, angioedema, nezvipusha, erythema, ganda akatsvuka, kuvaviwa uye mikoko. Uyezve, zvinoita zvinoderedza Chizenga indekisi uye kuwedzera huwandu uric asidhi uye creatinine nemhaka ingestion "Parnavel".