"Fosfomycin": analogues, mirayiridzo inofambiswa

Kunyange zvazvo antibacterial yomuchipatara vane vazhinji nemishonga, hakusi nguva zvichiita kuramba chikumbiro chavo. Chinhu chikuru kuti mushonga akasarudzwa nemazvo uye anopa zvinodiwa zvabuda.

High kunyatsoshanda pakurapa zvirwere zvakasiyana medicament "Fosfomycin". Drug analogues kunodarowo. "Fosfomycin" iri wakabudiswa muchimiro granules uye mvura-soluble upfu aiendeswa mhinduro, ine upamhi chakarondedzera inorwisa utachiona basa.

The mashandiro kuita zvinodhaka

Mishonga vanobudirira zvirwere vane kukura iri nokuda migumisiro iri muviri mabhakitiriya anokuvadza (giremu akanaka uye giremu kunaka). The inorwisa utachiona zvazviri kunokwanisika tichiregeredza yezviri fuma fosfomycin trometamol. Antibacterial richifanira kuitwa kutyora inotungamirwa kwemabhakitiriya muchitokisi masvingo.

Pharmacokinetics

Kana guru pfungwa yezviri chirungiso, kufadza vakachengeta zvinodhaka basa "Fosfomycin" aripo muropa plasma. Guide zvinoratidza kuti ichi ndicho maawa 2-2,5 pashure kupinda zvinodhaka mumuviri. "Fosfomycin" akakodzera parenteral uye kunanzvana yaitonga. Drug ingestion, nokukurumidza woga kubva nemudumbu, uye anotanga kupinda fosfomycin trometamol. Absorção de Água ari kuwanda 34% kusvika 65% (kudya kunoderedza indekisi, saka zviri nani mushonga drink usina chawadya). For hafu-upenyu hunodiwa 4 hr. Fosfomycin trometamol yabudiswa zvachose mutsvina yadzo weti uye, kunyanya nokuda itsvo (vanenge 90%).

zvairatidza

Kazhinji "Fosfomycin" analogs medicament chinobviswa nomuromo mu zvirwere nezvezvimwe zvinetso zvedundira. Drug akabudirira kurapa cystitis uye urethritis kwemabhakitiriya etiology, zvakawanda bacteriuria, izvo dzimwe nguva kunoitika vakadzi vane pamuviri uye anogona asingateereri unooneka. Munguva postoperative nguva, izvi mumiririri antibacterial kudzivisa chidzoke nezvirwere pathologies.

Kubayiwawo jekiseni kuratidzwa pakurapa vakawanda zvirwere kuti zvinobva kuparadzwa nemabhakitiriya muviri:

• purulent pleurisy;
• chenjera cystitis;
• pyelonephritis;
• adnexitis;
• septicemia;
• nemabayo;
• bronchiectasis;
• pelvic chirwere.

In Muzviitiko zvakaipisisa wemishonga kurapwa zvichibvira, kunze apo "Fosfomycin" mamwe kushandiswa inorwisa mabhakitiriya. Kumboda "Fosfomycin" (analogs) rakashandiswa pachiimbwa Beta-lactam inorwisa mabhakitiriya.

Contraindications uye zvausingakwanisi

The mushonga hauna chinotarisirwa panguva yakakwirira aikanganiswa yezviri chirungiso uye ebetsero zvinoriumba. The mushonga ari contraindicated varwere vari kuwana renal kutadza (creatinine Clearance asingasviki 10 ML / min.).

Kana kutyorwa "Fosfomycin" mashandiro anoita chiropa uye itsvo yaishandiswa nokungwaririra panguva nepamuviri uye lactation - chete pasi pokudzora nyanzvi.

shoma kushandiswa chinodiwa pakurapa varwere pasi pemakore 5 makore nemakore 75 (vana pasi 5 years "Fosfomycin" ushandiswe isingawanzowanikwi).

Kushandiswa "Fosfomycin"

Inside kushandiswa pellets kare zvazvichanyungudutswa mvura majekiseni kutora injectable mhinduro wakagadzirirwa kubva upfu "Fosfomycin" gadziriro. Analogs, uye ichi chokushandisa rinoshandiswa mishonga ndakarumbidzwa iri kupinda chiremba. The chipimo chemushonga kunobva chirwere chacho kukuvadza.

Murayiridzo zvinoreva kunonyanyisa chipimo chemushonga hwacho kana Ingestion: vana - 2 magiramu pazuva, nokuti vakuru - 3 magiramu pazuva. Mwana anogona kupiwa nomutsinga hapana zvinopfuura 100-200 MG / makirogiramu muviri uremu, mukuru - kwete kupfuura 2-4 d Granules kamwe vatora, usina chawadya kana 2 maawa pashure kudya. Panyaya iyi inotevera kudya zvinogoneka kwete kwokutanga pane pashure 2 hr. Zvinokurudzirwa kutora mushonga ndisati ndarara pashure nokuisa dundira.

nemishonga

Product ine fosfomycin trometamol, analogs ari mudziyo, uyewo mamwe mishonga inogona kutungamirira kukudziri- wanda ndisingadiwi. Zvinotevera kuvhiringidzika nemudumbu:

• changed mu chetsoka;
• flatulence;
• kuda kurutsa, zvichiteverwa kurutsa.

dzimwe nguva tsinga iri kuchengetwa wakawedzera kutya, dzungu, nomusoro, munhu nguva dzose vanoda kurara.

The majekiseni kunogona kukonzera marwadzo panguva jekiseni site kunzwa nyota. Pashure kwokubatsira zvinodhaka nenzira iyi vamwe varwere vane thrombocytopenia, leukopenia, kubva neutachiona - anaphylactic kuvhunduka, ganda kuvaviwa, mapundu, urticaria. Side migumisiro zvinosanganisirawo chitarisiko peripheral edema, uye pfari. Hazvina dziripowo kuratidzwa vamwe marwadzo.

In ovhadhozi Maitiro zvisingadiwi vanonyanyova raidudzwa. Zvakakosha kunwa zvinwiwa zvakawanda, mukuwedzera, zvinokosha kuita symptomatic kurapwa.

Ataura kuti divi migumisiro zvinodhaka "Fosfomycin" mirayiridzo Kurambidza mberi kwayo kushandiswa. Doctor zvinodhaka yokutsiva anofanira kuitwa.

Zvokungwarira

Zvinofanira kucherechedzwa kudyidzana zvinodhaka nezvimwe zvinhu. Hazvina varumbidzwa kutora ne "metoclopramide" zvinoreva, kureva. To. Mugumisiro ravo kwemajoini kushandiswa ndiko kuderedza kubudirira "Fosfomycin".

Usarerutsa mishonga pavarwere vari anongoti sema kuratidzwa. Sezvo mushonga zvinoenda mukaka, kurapwa panguva uchiyamwisa anofanira dzakavharwa kana akaita nokungwarira.

"Fosfomycin" analogues, anoreva zvakafanana zvinodhaka vari mapoka. Panguva kurapwa, mishonga haigoni uchashayikwa, zvakakodzera kushandisa yokuchengeta yakaenzana zvikamu. Kana paiva vanopfuura runodiwa dose inofanira kutorwa se (chete chiitiko kuti hazvina zvakakodzera kutora inotevera dose munguva yemberi iri pedyo) nokukurumidza sezvinobvira.

Analogs Wongororo

Asi, mushonga "Fosfomycin" rinogona kushandisirwa mishonga, analogs uye zvinodhaka-anoreva zvakafanana. Asi vanofanira kusarudza kurapa chiremba. Zvinokosha kucherechedza kuti "Urofosfabol" uye "Monural" rinowanzoshandiswa pachinzvimbo nyaya maturusi. Vanogona kuva zvikuru kubudirira kutsiva "Fosfomycin". Analogues muUkraine akauya nezvinodhaka izvi. zvinodhaka aya zvakanaka kukunda mabasa uye zvinogona kushandiswa kurapa zvirwere dzakafanana "Fosfomycin". Kufanana nevamwe antibacterial vamiririri, vane zvimwe nemishonga. "Urofosfabol", "Monural" atora nokungwaririra akaipisisa, zvimwechete chinoshanda mushonga "Fosfomycin". Ishamwari muRussia, inova yakakurumbira kupfuura - "Monural", asiwo "Urofosfabol" vanewo Pharmacies.

"Monural" rinowanzoshandiswa nachiremba pakurapa chakasimba Urinary turakiti zvirwere izvo kuitika pasina yematambudziko akakonzerwa tusingaoneki nyore kuti zvinodhaka. The chinodhaka rinoshandiswa akavhiyiwa uye chirwere dzokuvhiya. "Urofosfabolom" kubata zvinotapukira uye anogumbura zvirwere, asi vaya chete vari kubvuma basa zvinhu. Pane nzira shoma kuti anogona kutsiva "Fosfomycin". Analogues rweUkraine uye Russia vanoshandisa chete.

Reviews anoratidza kuti "Fosfomycin" havangagoni kuwanikwa Pharmacies, uye mari zviri kumusoro, kwete vose vanogona kutenga. Asi "Monural" nguva dzose kuwanika. Zviri isingadhuri, asi haaiti zvakaipa. Vaya vakagamuchira "Fosfomycin" chiziviso kuti ane zvinozoita nokukurumidza zvakakwana. Zvisinei, haasi munhu wose anoona pane zvakanaka kuchinja. Dzimwe nguva, kuti kurapa chirwere, zvakakodzera kugadza mumwe mushonga. Mune zvimwe zviitiko, divi kuitike, kureva. K. The muviri mumwe munhu vakasiyana uye anopindura zvinhu varipo gadziriro zvakasiyana.