Duchenne myopathy - chirwere tsinga.

Zvirwere tsinga vagara zvakurukurwa pakati kwazvo uye akaoma-kuti-zvinodhaka mishonga pathological ezvinhu. Izvi imhaka yokuti tsinga ndiye zvemberi uye kusiyaniswa zvikuru marongerwo womunhu muviri, masero izvo zvinenge zvisiri kurapo pacharo. Kana paine kuparadzwa chete tsinga faibha, chiitiko ichi zvachose kusingarapiki. Mugumisiro izvi kuchaguma zvachose kurasikirwa dzichipfekeka unyanzvi pakati anatomical nharaunda, nokuti idzo tsinga fibers kundochingamidza vakarasika. chetsinga kunyongana kuzhinji dzinokonzerwa vaberekwe vakaremara kuti zvinogona kutapukira kubva kumarudzi namarudzi.

A wakadzama muenzaniso pathological mamiriro kunokonzerwa nhaka myopathy ndiye Duchenne. chirwere chakadai chinopfuudzwa ari autosomal recessive nhaka maitiro uye zvakawanda pachena pakati hono vakawanda redu. Zvapedzisira Chokwadi ndechokuti nokuti chokuti nhaka ane chokuita zvepabonde okutodza. Panguva mwoyo chirwere zviratidzo kuremara mhosva kwetunhu zvinokosha dystrophin mapuroteni, izvo zvinobatanidzwa pakuchengetedza anatomical nemamiriro tsandanyama faibha. Nokuda kwokushayikwa puroteni dystrophin tsandanyama rinenge kaviri nhevedzano kuchinja semubairo iyo tsandanyama inotsiviwa fibrous uye mafuta rinenge mune mamwe manzwi, zvichava atrophy. Nokuti kuti Duchenne myopathy chichigarwa nhaka, rwunotanga kuonekwa sezvo mangwanani sezvo paucheche. Vabereki kuteerera chii mwana wavo matai nyore kubva kuchangotanga mumuviri nesimba, inova usimbe, nokukurumidza iye anogona kunyange kuchinja gait uye akaremara mapfupa marangwanda.

Naizvozvo pathological muitiro mberi chete kubva zviri pasi zvachose vose tsandanyama dzemuviri. Nokuti zvokurwara ichi kunoratidzwa myopathy ziso. More tsandanyama vanokanganiswa nemakumbo, mutumbi, mwoyo. Kana myocardial kubatanidzwa pane cardiomyopathy yechipiri, wakaputsika mwoyo mutinhimira. Kazhinji ndiwo zvokurwara pakati kumwoyo iri huru kukonzera rufu varwere chirwere pakati Duchenne myopathy. Okunyanyisa nzira kurapa chirwere ichi ichiri asipo. Inokosha kurapwa - ndiko kuvandudza uye kuwedzerwa upenyu hwevanhu.

Myopathy Duchenne inogona ndanyarara hangu kwenguva refu, kuburikidza nokugamuchira zvinodhaka corticosteroid. Paavhareji, murwere nezuva vanoda vanenge 800 MG ose prednisolone chete kilogram kurema muviri. In kwokutanga matanho anoshanda chaizvo mapuroteni zvivako dzakakwirira zviri amino acids, anabolic steroids, kuti zvose zvinogona kukurudzira tsandanyama kukura. Marapirwo kunodiwa kuti zvinosanganisira L-carnitine, mishonga vasoactive, mavhitaminzi (B1, B6, B12, etc.) Biogenic stimulators (Aloe), Alpha-lipoic acid, zvinhu kubva boka antioxidants. In vamwe ichi zvokurwara kurapa zvinofanira kuitwa, izvo kuvandudza trophism iri musculature. Izvi zvakasiyana physiotherapy unyanzvi, panyama kurapa zvemusangano uye nguva dzose dzokurapwa masaja. Zvose izvi zvinobatsira kuderedza kuchiita chirwere uye pave kwemajoini uye tsandanyama contractures, izvo kukutadzisa injini basa murwere kwazvo. Kuderedza kuomarara vachibatsira kushandiswa zvigadziriswe siyana uye zvakagadzirwa. Muzviitiko zvakaipisisa, kana iziviswe contracture uye kudzivirira kwete chete kufamba, asi kunyange kugara uye nhema kuti kumhanya palliative kuvhiyiwa.