Wiskott-Aldrich chirwere: rondedzero chirwere

Wiskott-Aldrich chirwere ndiyo nhaka chirwere chinobata chete vakomana. Kunoratidzwa muna muduku uye yemanyorero inotungamirira kurufu mukati mashanu gumi makore.

Kokutanga hosha paakarondedzerwa muna 1937 ne wevana wokuGermany Wiscott. Akatarira kubva nevanin'ina matatu, uyo akatambura vaingogara reropa manyoka, eczema uye kugara kuzvimba nzeve, kunyange hanzvadzi dzaiva ina zvachose utano. Nechekare muna 1954, American wevana Aldrich mazita vakawana kuti hosha iri nhaka ive X-chokuita recessive unhu.

The chirwere iri chakasvitswa vakomana uye mutakuri kusachinja okutodza vakadzi. The nenzvimbo chinhu asina sei kwakaita dambudziko.

Zviratidzo zviri chirwere

Wiskott-Aldrich chirwere Rinobatanidzwa kuderedzwa platelet count. Mumakore okutanga oupenyu murwere rinoratidza zvinotevera zviratidzo: murombo kweropa, kuramba eczema, ropa manyoka. Zvadaro, pane chikuru immunodeficiency. Nokuda kwokushaya T uye B lymphocytes munhu ari pasi zvose zvemarudzi nemavhairasi uye kwemabhakitiriya zvirwere. Immunodeficiency muvana vanotsamwisa zvechigarire pakati nzeve utachiona, mabayo, sinusitis, norukandwe nezvimwe zvirwere zvakawanda zvakakomba. Tichitambura kubva chirwere kwakakwirira chaizvo nechirwere. Zvinofanira kucherechedzwa kuti malignancy kazhinji pachena vakuru.

Tichitambura kubva chirwere Viskota-Aldrich chirwere rinowanzoshandiswa kuchengetwa chete Hemorrhagic chirwere, iyo inosvitsa isiri zviratidzo. Muzviitiko zvakadaro, chete pashure DNA pachisara umo zvinokwanisika kuziva majini anokonzera chirwere varayire kurapwa.

Diagnostics

• A kwakakwana ropa count kuziva zvinoderedza kwenhamba maplatelet.
• Kudzidza ropa zodzera pamusoro STRUCTURAL kushayiwa maplatelet.
• Genetic kuongorora (aitira Detective kunotouraya ari Gene anokonzera sechivako puroteni muropa).
• Pakusarudza padanho immunoglobulin.
• Kuitisa pamuviri nechirwere, kuona Wiskott-Aldrich chirwere mukutanga pamuviri.
• Kutsunga mapuroteni muropa kwevari Wiskott-Aldrich syndrome.

mabatiro

Zvinosuruvarisa sayenzi yemazuva ano asati awana mushonga chirwere ichi chinopedza simba. Zvinozivikanwa kuti maplatelet vanoparadzwa ari chirwatata, saka varwere vanenge chirwere "Wiskott-Aldrich Syndrome", akabviswa nedare. Uye varwere vakatanga kunzwa zviri nani zvikuru. Constant kuwedzerwa immunoglobulin uye kugadzwa inorwisa mabhakitiriya zvakakodzera uyewo anovandudza mukuru ezvinhu omurwere. Pari muitiro kudzidzisa varwere mumwongo utano hunde masero. Asi apo nzira iri kuitwa chete chiedzwa. Uyewo vakaroorana takambova chirwere ichi mumhuri, Zvinokurudzirwa zvakaitika miedzo zvose zvakafanira vasati kuronga pamuviri.