The mushonga "Ofloxacin": Murwere uchapupu. Mirayiridzo kushandisa mushonga "Ofloxacin"

Kugadzirira "Ofloxacin" ratings varwere izvo kazhinji akanaka, rinomiririra inorwisa utachiona mutumwa kubva boka fluoroquinolones chakarondedzera basa. Chezvinodhaka chinobata DNA gyrase - kwemabhakitiriya kukamuka, ichipa supercoiling uye saka kutsiga utachiona DNA (somugumisiro destabilization DNA beach achifa).

pharmacodynamics

Rinoreva "Ofloxacin" - mushonga unorwisa inobudirira panyaya tusingaoneki kuti pave Beta-lactamase, uyewo kukura nokukurumidza atypical mycobacteria. To mishonga inoshanda, vakawanda giremu negative utachiona, kusanganisira tusingaoneki husingakwanisi methicillin nezvimwe inorwisa mabhakitiriya. Streptococci, enterococci, uye Mycobacterium tiibhii vanoonekwa ne kusagadzikana susceptibility kuti mushonga "Ofloxacin". Reviews kuvarapi anoratidza kuti pakurapa anaerobic zvirwere zvinokonzerwa peptostreptokokki, peptokokki nezvimwe anaerobes, mushonga kazhinji isashande.

Pharmacokinetics

Pamusoro pokugamuchira medicament kupinda Absorção de Água zvakakwana (95 muzana) uye kutsanya. Bioavailability - zvinopfuura 96 muzana. Ukama kuti mapuroteni eplasma - 25 muzana. Pashure mumwe maviri maawa pashure nomumukanwa kwokubatsira chemhando wevasungwa kuenzana. Zviri dose-hunotsamira: chete kushandiswa mazana maviri, mana kana mazana matanhatu milligrams zvinodhaka wevasungwa akanga azvaitwa 2.5, 5 kana 6.9 ug / Rine mamiririta.

Food kunwa kunogona kukanganisa Absorção de Água ari divi rimwe slowdown, asi hapana chinokosha chaizvo bioavailability. Kugadzirira "Ofloxacin" - mushonga unorwisa ane zvokutora Vhoriyamu nokuparadzirwa (zana marita), saka kuti raitongwa gadziriro iri anenge mari yakazara chinopinda pachena mumakamuri. The soro kuwanda vari munyama, zvinwiwa muviri uye nhengo: ari mumasero (alveolar macrophages, leukocytes), nyoro zvinyama, ganda, mapfupa, kufema maitiro, pelvic uye abdominal mhango, nemate, prostatic secretions, weti, bile. The medicament tsime kupinda munharaunda yacho placental uye ropa-pfungwa mhinganidzo, iri secreted kubva mumukaka, uye cerebrospinal mvura inopinda panguva asiri zvomoto uye zvomoto pfungwa membranes (14 kusvika 60 muzana).

About 5 muzana zvinodhaka rinoita ari chiropa yokuumba dimetilofloksatsina uye N-oxide kuti ofloxacin. Pasinei dose hafu-upenyu pakati mana nehafu kusvikira maawa manomwe. Output kuchinja mushonga mune mari 75-90 muzana itsvo, mune mari 4 muzana - iri bile. Asingasviki 20 muzana extrarenal Clearance. Pashure chete dose mazana maviri milligrams kuti mumiririri riri detectable ari weti kwemaawa 20-24. Kana hepatic kana renal excretion anogona seiyi. Kana dialysis yabviswa ne 10 kusvika 30 muzana mishonga.

zvairatidza kuti

In yezvirwere uye anogumbura zvirwere zvinokonzerwa tusingaoneki siyana, kuratidzwa ndikarangarira medicament "Ofloxacin". Reviews akashuma kuti zviri kwazvo zvakanaka kufema turakiti zvirwere (nemabayo, bronchitis), rokumusoro kufema turakiti (otitis nhau, sinusitis, laryngitis, pharyngitis). Ipa mushonga mu dzakapfavirira zvinyama maronda, majoini, mapfupa, ganda, turakiti biliary, Urinary turakiti (urethritis, cystitis), itsvo (pyelonephritis), abdominal mhango, nhengo dzokubereka nadzo (orchitis, colpitis, epididymitis), pelvic nhengo (salpingitis, prostatitis, cervicitis, endometritis, oophoritis, parameters).

Uyewo inoshanda mushonga nokuda ureaplasmosis, chlamydia, mwandabvu. Kurishandisa kudzivisa noutachiona varwere kusagadzikana masoja chinzvimbo (kusanganisira neutropenia).

The chipimo chemushonga fomu. mamiriro

Kubudiswa medicament iri muchimiro Coated chena kana anenge chena mahwendefa film-zvemapuranga biconvex kumativi chimiro. Muchinjikwa sectional kuoneka maviri akaturikidzana, mumwe iro rine yellowish tint. Active pamashandiro anoita se ofloxacin. Mumwe piritsi huri vazhinji 200 kana 400 MG. zvimwe Minor vari primelloza (croscarmellose yavaibvisa), microcrystalline cellulose, Aerosil (colloidal nesilicon yakasviba), silica titania, povidone, hydroxypropyl methylcellulose (hypromellose), talc, magnesium stearate, polyethylene glycol 4000 (macrogol). A mukana guru zvinodhaka "Ofloxacin" - mutengo. Mahwendefa ane 200 MG ose vanoshingaira fuma vari avhareji 16-20 rubles por zvidimbu 10, uye avo kuti ane 400 milligrams ofloxacin, achaita mari vanenge 50-55 rubles muzana zvidimbu 10.

"Ofloxacin" mushonga. Mirayiridzo yokushandisa

Mahwendefa vanofanira kunwa usati kana pashure zvokudya. Vanofanira kumedzwa yose, pasina kutsenga, uye kunwa mvura munzvimbo diki zvakawanda. The chipimo chemushonga anofanira kusarudzwa nomumwe zvichienderana kwokuomerwa hosha, kuti localization ari chirwere, murwere rwevanhu ezvinhu, itsvo basa, chiropa, uye utachiona nehanya.

Kazhinji, pakurapa "ofloxacin" chinoitwa kuti manomwe gumi mazuva. Adult daily ushandiswe yaunodya mazana maviri, mazana matanhatu milligrams kaviri pazuva. The dose anogona ngazviwedzerwe milligrams sere kune chakakomba chirwere, kana kana murwere ari kufuta. A dose pamusoro milligrams zvina dzinogona kutorwa kamwe, kunyanya mangwanani.

Varwere havachanyatsogoni renal nerevane kamwe haagoni kutora anopfuura mazana maviri milligrams zvinodhaka, kufadza dose zuva nezuva hepatic vanotaura - milligrams mazana mana. Pashure kunyangarika zviratidzo uye normalization kuti tembiricha, kunyange kwemazuva maviri kana matatu kuramba kurapa.

Marwadzo. Testimonials

Havasi varwere vose mushonga "Ofloxacin" zvakanaka zvaitombova. Reviews vamwe vanhu ane ruzivo kuti zvinodhaka hunokonzera nemusoro, kuda kurutsa, kurutsa, manyoka, chakamira pakunodengenyeka zvine, chiveve kuti wamativi. Pamusoro chikamu zvomudumbu ino anogona kuva sezvo abdominal marwadzo, gastralgia, bloating, cholestatic jaundice, kudya hyperbilirubinemia, pseudomembranous enterocolitis, uye tsinga - kushayikwa rwokufamba, chinyamunhari chinorwadza, zviroto zvikuru, pfungwa siyana, nokusagadzikana, kufunganya, kuvhiringidzika, phobias, zvisipo, kuora mwoyo.

Uyezve, pane ngozi yokutyora injini system (arthralgia, tendonitis, myalgias), pfungwa (kuravidza zvinetso, ruvara chiratidzo, kunzwa, nepakati, kunhuwidza), vascular hurongwa uye mwoyo (zvinoderedza BP, tachycardia), ganda (dermatitis, pfungwa ropa, papular mapundu), kuti hematopoiesis (thrombocytopenia, kupererwa neropa, leukopenia). Pashure pokugamuchira "Ofloxacin" chinodhaka (wongororo zvinoratidza izvi), mune zvimwe zviitiko ikaramba itchy ganda, bronchospasm, urticaria.

Contraindications

Kugamuchira medicament wakarambidzwa kusawirirana ofloxacin uye dzimwe fluoroquinolone nomukaka, panyaya kushayiwa shuga-6-phosphate dehydrogenase, pfari, maronda ari nemarunda, nokuderedza kufenda pachikumbaridzo. Uyezve, haukwanise kutora zvinodhaka "Ofloxacin" vakadzi pamuviri uye lactating, vana pasi pemakore gumi nemasere. With kunyatsogadzirira iri nachiremba kweropa zvinetso muuropi, chepfungwa vascular atherosclerosis, renal kukundikana chisingaperi CNS maronda makemikari hunhu.

Medicament "Ofloxacin" panguva imwe ureaplasma. Reviews

The chikuru ndechokuti vanhu vanoti, vanoshandisa chigadzirwa - ndicho ake nokukurumidza nomugumisiro. Varwere vanotaura kuti izvi zvinoita kuoneka kare panguva yechitatu kana rechina zuva. Asi zvakafanira kunyevera kuti izvi hazvirevi kutanga mushonga. varwere vaya vasingachaiti kunwa mapiritsi, pasina dzichidzidzisa zvizere Chokwadi, ipapo zvakare akanzwawo ureaplasmosis zviratidzo, nekuti utachiona vasina zvachose chapedzwa.

Zvokungwarira

Kana nemabayo kushatiriswa pneumococcus, nokuishandisa isashande. Uyewo, hazvina akaratidza kuti mishonga rikwanise tonsillitis. Zvakakodzera kumisa mushonga kana iri pakanyorwa kubvuma kwake kunzwa sema maitiro, ari CNS wenyonganyonga, pseudomembranous colitis. Women kushandisa rinoreva "Ofloxacin", hazvina varumbidzwa kushandisa tampons, nokuti iyi pane mikana yokuita thrush.