"DioCore 160": mirayiridzo kushandiswa, dzomuzana chaivo. "DioCore Solo 160": mirayiridzo kushandiswa, zvechokwadi

The yakakura nhamba yevanhu neapo vanotambura cheBP. Zvisinei, yakadaro pathological mamiriro kwete chete kunounza inokosha kusanzwa murwere, asi anotyisidzira upenyu hwake. Saka, mazuva ano mishonga musika pane zvakawanda kuti pave BP.

Zvikuru akakurumbira pakati vanhu vaya vanogara kutambura BP, anoshandisa mushonga se "DioCore 160". Mirayiridzo yokushandisa, analogues emishonga ichi, uyewo wongororo nezvazvo, zvinhu uye zvivako zvichakurukurwa gare gare.

Zvinoumba, description, kavha uye chimiro

Medicine "DioCore 160", mashoko zvirimowo mubhokisi chakagadzirwa makadhibhokisi, kugadzirwa muchimiro mahwendefa. Ndivo firimu-Coated uye ane zvinhu zvakadai achishingaira sezvo valsartan uye hydrochlorothiazide. Uyewo nhau rinoreva zvinosanganisira microcrystalline cellulose, yavaibvisa lauryl sulfate, mbatatisi starch, talc, chibage starch, croscarmellose yavaibvisa, magnesium stearate, colloidal anhydrous silica uye opadry II Orange.

Hatigoni kutaura kuti mushonga wakadaro, uye anogona kuwanika kutengeswa sezvo "DioCore Solo 160". Kubva yakapfuura zvakasiyana pakuti chacho vanoshingaira chirungiso anoita chete valsartan.

Nheyo kushanda ane medicament

Chii chinodhaka "DioCore 160"? Mirayiridzo dzokushandisa inoti ichi antihypertensive mumiririri, iro rinoumbwa munhu thiazide diuretic uye angiotensin II Kanotokonya antagonist.

chokushandisa ichi ane zvakawanda vasiri migumisiro inonwiwa sezvo zvisina kunanga uye yakananga chikamu BP murau. Angiotensin II munhu simba vasoconstrictor mumiririri yakakonzerwa zvakananga pressor maturo. Rinotaurawo rinononotsa ari yavaibvisa uye zvinoita secretion kuti aldosterone.

Valsartan akadana vachishingaira uye yakananga angiotensin II Kanotokonya antagonist. It rakagadzirirwa nomumukanwa Kutarisirwa uye zvokusarudza kuita pamusoro AT1 Kanotokonya subtype kuti vane basa zvinokonzerwa angiotensin II. Mienzaniso agonist basa panguva Kanotokonya subtype AT1, maatomu akafanana izvi hazvirevi kuratidza.

Uyewo valsartan kwete tunodzivisa ACE, izvo vatendeuki angiotensin I kuti angiotensin II, bradykinin rinoparadza. Not akacherechedza uye mamwewo matambudziko anokonzerwa bradykinin.

In vanhu vane BP, mushonga rinoita vasanyanye BP. Muchiitiko chino, hakuna kumbochinja kwemwoyo.

Varwere vakawanda pashure chete dose of nyaya zvinodhaka kutanga antihypertensive basa aona mukati 2 maawa, uye BP rutapudzo pamusoro maawa 6.

The antihypertensive mugumisiro zvinodhaka hunoramba kwenguva inopfuura zuva. Nguva piritsi kunonyanyisa kuchirapa kushanda kunokwanisika mukati masvondo mana uye ainawo nzira yokurapa-refu.

Pharmacokinetics

Ndezvipi yokusafa kinetic ehupfumi ari medicament "DioCore 160"? Mirayiridzo dzokushandisa (mahwendefa zvinofanira ushandiswe chiremba chete) rinoti pashure kutora mushonga mukati Absorção de Água kuti hydrochlorothiazide uye valsartan ndiko kutsanya chaizvo. The paavhareji Mhedziso bioavailability kuti mumiririri uyu 23%.

The kinetics pamusoro valsartan vari Linear. Akadzokorora kushandiswa kwezvinodhaka haabati chero kuchinja. Rimwe chete piritsi kuti kuwanda kwavo kunyora nezvavo.

Valsartan anosungwa kuti mapuroteni eplasma pa 94-98%. excretion Its rinoitwa pamwe mutsvina yadzo weti uye. Kana ikatorwa pamwechete AUC pamusoro valsartan zvokudya kuderedzwa 48%.

Pashure pokugamuchira Mahwendefa mukati hydrochlorothiazide Absorção de Água kunoitika asi nokukurumidza (maawa anenge 2). Uyezve, ayo bioavailability ndiyo 60-80%. Anoratidza panzvimbo weti.

Tiine zvaainazvo valsartan uye hydrochlorothiazide systemic bioavailability weava ipfupi ne vanenge 30%.

zvairatidza mahwendefa

Under chii ezvinhu murwere anogona yakatarwa zvinodhaka "DioCore 160"? Mirayiridzo yokushandisa, vanachiremba chaivo dzinoshuma kuti chokushandisa uyu kwazvo pachena pacharo mu neBP, uyewo kushaya kubudirira chirwere ichi bedzi.

Contraindications kugamuchira mapiritsi

Waizviziva here kuti mune zvimwe zviitiko, kwete ushandiswe mapiritsi "DioCore 160"? Manual rinoti mushonga kwakadaro contraindicated mu nomumwe kusada zvayaigadzirwa.

Uyezve, hakubvumidzwi dzokushandisa varwere cholestasis, zvakakomba chiropa vanotaura, uye biliary cirrhosis. Uyewo, hazvina haungopiwi vanhu vanotambura chero zvakakomba uye nepakati renal dysfunction, chiratidzo pakati anuria, akaderedza yavaibvisa uye potassium mumatunhu muropa, hypercalcemia uye hyperuricemia.

Mahwendefa "DioCore 160": mirayiridzo kushandiswa

Kazhinji, kubvisa cheBP pamba varwere vanokurudzira kushandisa rimwe piritsi "DioCore 80" kamwe pazuva. Kana "DioCore 160" zvinodhaka, zvakanyorwa ushandiswe chete muchipatara. Panyaya iyi, murwere unofanira kuva pasi kuramba pokudzora chiremba.

Sezvo tsika inoratidza imwe kuoneka kushanda nesimba neBP vakachengeta mavhiki 2-3 pashure mharuro mushonga.

Nokuti vanhu vane mwero kana chinokosha hepatic kana renal vanotaura kunodiwa kuita zvakakodzera kutsiura ari chipimo chemushonga siyana (nomumwe).

Ya kurapwa nemishonga iyi tinofanira kutsunga chete kupinda chiremba.

nemishonga

Imhandoi nemishonga kuti murwere vanofanira kuziva usati kushandisa mushonga "DioCore Solo 160"? Mirayiridzo Dzokushandisa rinoti vaiona mushonga kazhinji kunokonzera yaivhuvhuta zviitiko zvine kusagadzikana uye vachirwara-yakajeka hunhu.

Anenge 1% wevarwere apo kutora zvinodhaka uku akazviratidza simba nomusoro, musana marwadzo, kurukutika, chikosoro, dzungu uye nasopharyngitis.

Asingasviki 1% chema abdominal marwadzo, kufunganya, kusagadzikana mune pamutsipa uye muchipfuva, kurukutika, kurwadza kwemajoini, serous bronchitis, hope, laryngitis, kupfupika mweya, manyoka zvirwere, akaderedza erection, kuderera salivation, hypotension, gastroenteritis, paresthesia, wakawedzera vangadikitira, ungaderedza nehanya, tsandanyama chinyamunhari chinorwadza, kushaya hope, peripheral edema, kuda kurutsa, nzeve zvirwere, nasal kuzara uye zvishoma kuwedzera kupisa muviri. Dzimwe murwere vasingadzoreki chiratidzo, kusagadzikana tachycardia uye tinnitus. Zvinofanira kucherechedzwa kuti zvakananga noukama panowanikwa siyana izvi uye mushonga haina dzatangwa.

Ndezvipi zvimwe nemishonga inogona kukonzera nemishonga "DioCore Solo 160"? Instructions ari kushanda rinoratidza kuti kana vachishandisa nzira iyi, kwaiva kure zviitiko kutanga mapundu, kuvaviwa nezvimwe sema kuratidzwa, kusanganisira vasculitis, uye serum kurwara. Uyezve, varwere dzimwe nguva kuva myalgias uye nefralnaya dysfunction.

Very isingawanzowanikwi chimiro nemishonga kana achitora "DioCore 160" chigadzirwa chiri nyore non-cardiogenic edema kuti chokuita nomumwe kusada hydrochlorothiazide.

Ongororo dzakaratidza kuti mune vamwe varwere kubatwa chokushandisa ichi, ungaderedza potassium muropa, Kusimudzira creatinine uye urea, uyewo kuona munyoro neutropenia.

Zviratidzo ovhadhozi

Ndezvipi zviratidzo "DioCore Solo 160" vaine mishonga zvinodhaka? Manual rinoti nyaya dzakadaro vasingazivikanwi panguva ino.

The chikuru chiratidzo yakawedzera dose kurapwa kunogona kuva chakakomba hypotension. Kana mushonga rakazoshandiswa tichishandisa yapfuura, munhu anofanirwa artificially kunyengedza kurutsa. Uyewo revarwi hypotension anogona kuitwa intravenous kwokubatsira kwomuzvarirwo sesaline.

Zvinofanira kurangarirwa kuti hazvibviri kuti kuona kuti vaiona chinodhaka kubva muviri hemodialysis. Izvi imhaka yokuti valsartin, akabatanidza kwaro sezvamunoita, izvozvo zvaanoita pamwe mapuroteni eplasma. Zvisinei, zvinofanira kucherechedzwa kuti hydrochlorothiazide panobviswa nenzira iyi zvikuru zvinobudirira.

Drug aiita vamwe mishonga

Zvinoita chokubatanidza nevamwe rinoreva "DioCore 160"? Instruction inoti kuti mubatanidzwa zvinodhaka ichi nevamwe antihypertensive zvinodhaka boka kunogona kukonzera kuwedzera migumisiro BP.

Kushandiswa mawa pamusoro medicament pamwe potassium tubhokisi yokuvirisa, nyoro diuretics, solezamenitelyami uye zvinhu kuti vawedzere zviri potassium pamuviri, zvinoda kugara bvunzo wevasungwa kuti potassium muropa serum.

Apo mawa Kutarisirwa kwezvinhu "DioCore" pamwe ACE FIs vave kuzivikanwa reversible kuwedzera wevasungwa kuti lithium muropa.

Chii mishonga anogona zvakachengeteka kushandisa zvinodhaka "DioCore 160"? Guide anoshuma kuti monotherapy neBP chokushandisa ichi haina kuchengetwa chero kudyidzana ne "glibenclamide", "amlodipine", "warfarin", "cimetidine", "Digoxin", "furosemide", "indomethacin" Atenolol ".

Sezvo mushonga ari murwiyo pasi kufunga zvinosanganisira thiazide diuretic boka, ayo fungidzira zvinotevera mukukurukurirana:

• kuderera mune diuretic mugumisiro zvinodhaka kana rinoshandiswa pamwe NSAID (semuenzaniso, salicylates kana "Indomethacin");
• potentiation kuti tsandanyama relaxants.

Ndezvipi zvimwe zvinodhaka mukukurukurirana vanofanira kuziva asati atora "DioCore 160"? Instructions, ongororo dzinoratidza kuti apo kushandisa ichi mudziyo pamwe kaliynesberegayuschimi diuretics, salicylates, ACTH, amphotericin karbenokslolonom uye zvichida unopinza vasanyanye wevasungwa kuti potassium muropa.

Kana akashandisa injectable uye dzaiita mishonga antidiabetic yaifanira nomumwe kuchinja chipimo chemushonga yavo.

Hazvina yakarumbidza kushandisa vaiona medicament pamwe diuretics thiazide boka, sezvo izvi zvinogona kutsigira-vataurwa pamusoro divi anokonzerwa zvinodhaka uye kuti hypersensitivity zvavaifunga.

Kana rikashandiswa panguva imwe chete methyldopa hydrochlorothiazide zvingamuka hemolytic kupererwa neropa.

Kana mushonga zvabatanidzwa "DioCore 160" pamwe kolestiraminom zvinoderedza ayo bioavailability uye Absorção de Água.

Pamberi mushonga pamwe vhitamini D muropa karusiyamu wevasungwa anogona zviwedzerwe varwere.

Zvinonzi rambidzwa kutora "DioCore" pamwe cyclosporine, sezvo izvi zvinogona kukonzera zviratidzo uye mamiriro podagropodobnye giperurikekii.

Dzinenge kurumbidza pamusoro piritsi

Zvaunofanira kuziva usati kushandisa zvinodhaka "DioCore Solo 160"? Mirayiridzo yokushandisa, wongororo vanoti panguva kurapwa pamwe mumiriri iyi murwere vanofanira kugara richiona nezvezvabuda serum kwevari electrolytes muropa.

With kukura sei hypotension vatendeuke kuva chinjikira chinzvimbo. Kana waida, kuita intravenous aizomupa kwomuzvarirwo sesaline. Mushure pakudzikamisa kumanikidza kurapwa kunogona mberi.

Vanhu vane yaitsigira divi kana bilateral renal tsinga stenosis kugamuchirwa valsartan kungaita kuwedzera serum creatinine kana ropa urea.

Kana hurukuro yacho medicament varwere vane havachanyatsogoni itsvo basa dose kuchinja kunodiwa, asi kunoda nguva nenguva richiona nezvezvabuda creatinine uye uric acid, uye potassium zviri ropa.

Pane uchapupu hwokuti thiazide diuretics kunogona kuwedzera chinonzi systemic lupus erythematosus. ivo kuchinja shuga achishivirira murwere, kuwedzera wevasungwa pakati remafuta akawandisa, uye uric asidhi muropa triglyceride. Panyaya iyi, varwere chirwere cheshuga kungada kuchinja kubva dose nomumukanwa hypoglycemic nevamiririri kana jekiseni.

In varwere mwero uye zviduku chiropa vanotaura pasina cholestasis ari dose kuchinja kunodiwa. Asi pasi izvi ezvinhu mushonga inofanira kubatwa nokungwarira zvikuru.

Pane mishumo photosensitivity panguva kurapwa pamwe thiazide diuretics. Kana mukufamba mishonga iyi zvinoreva pane zvakaitwa photosensitivity, kurapwa kunofanira vakarega.

Kana zvakakodzera, vaitarira akadzokorora imwe diuretic inokurudzirwa kuchengetedza zvikamu vanotambura chakagadzirwa ultraviolet mwaranzi kana zuva.

zvinodhaka analogues

Chii chinogona kunzi kuti kutsiva dzedu nzira? Maererano nenyanzvi ehupfumi akafanana vari zvinodhaka akadai "Air-gungwa", "Dentokind", "Intsena", "Cinnabsin", "Softovak", "Medotsef" "Vinblastine-din email".

Reviews kugadzirira

Zvino kuti munoziva kuti kushandisa zvinodhaka "DioCore 160". Mirayiridzo Kushandiswa mushonga uyu akarondedzerwa zvizere kumusoro.

chokushandisa ichi kwakakurumbira chaizvo pavarwere uye n'anga. Nyanzvi dzinoshuma kuti zvinobudirira hworatidza pacharo pamberi zvikuru arterial hyperplasia isiri yekenza. Vatengi zvakazara anobvumirana neizvi. Maererano mhinduro dzavo, vachitora mumwe hwendefa inosimudzira kudzorerwa BP, uyewo aivabatsira avo ezvinhu.

Hazvibviri kuona chokwadi chokuti mushonga une mukana chimiro yokusunungurwa chipimo chemushonga. Zvisinei, kutora wakakwirira dose zvinodhaka kunofanira chete kuva muchipatara, pasi pokudzora chiremba.