The mushonga "metipred" zvaanoda? "Metipred": zvairatidza yokushandisa

Vamwe zvirwere zvinogona kuitika neumwe nemishonga zvinodhaka, t. E. Usava kupindura zvinodhaka kutarisira. Muzviitiko zvakadaro, sezvo mutemo, ivo vanoguma vava kushandisa glucocorticoids. Mumwe mushonga kwakadaro "metipred". Chii ushandiswe mushonga uye zvakafanana?

Chii chinodhaka ichi?

"Metipred" rinoreva boka chakaita zvokugadzirwa glucocorticosteroids, t. E. Kuri artificially synthesized kemikari analoginen. Rine Anti-anogumbura basa, rine Anti-sema zvazviri, kunoderedza edema, lowers basa anoverengeka rokuzvidzivirira, inodzorera metabolic zvirwere.

mashandiro ayo zvinoitwa inobva kumashoko dzakananga receptors iri nyama zhinji. By unobatanidza navo kuumba inokosha mapuroteni kuti vane basa murau pamusoro pezvakaitwa rinokosha.

The mushonga ane zvainoita mhando dzose metabolic pezvakaitwa pamuviri.

Sezvo zvinodhaka ndohwaJehovha boka glucocorticoids, zviri ushandiswe chete mune zvimwe zviitiko, kana pechingoro kunoreva kuratidzwa kuti kurapwa chirwere ichi vava isashande.

Mune zvimwe zviitiko, zvisinei, iwe ungashandisa "metipred"? Sei taurira izvozvo ichi kana kuti chirwere?

zvairatidza kuti

Chii zvirwere zvinoda kwavo mushonga kugadzwa hormone zvinodhaka? Kana zvirwere anoratidza "metipred"? Chii mushonga ichi ushandiswe?

Kugadzwa zvinodhaka wokutanga kunodikanwa systemic zvirwere connective tishu. Zvazvakadaro, vari: nechirwere chinonzi systemic scleroderma, systemic lupus erythematosus, vasculitis zvose, dermatomyositis. Muzviitiko izvi, kemikari rinobatsira kuderedza kuzvimba, kudzorera mukutsinhana ari sei nyama.

In rheumatology ari zvinowanzoshandiswa "metipred". Zvairatidza - yakakomba ingabatanidza anogumbura zvirwere mapfundo: arthritis, chearthritis uye psoriatic etiology, osteoarthritis, bursitis, synovitis, ankylosing spondylitis. The chikuru mugumisiro wacho mushonga mu zvirwere izvi - Anti-anogumbura uye marwadzo.

Zvinokwanisika kushandisa "metipred" iri Árbol asima uye zvakasiyana-siyana chirwere sema zvirwere.

chipimo chemushonga kuchinja

In chii mishonga chinoratidza kushandiswa "metipred"? Zvinofanira kurangarirwa kuti kugadzwa chinodhaka, uyewo mamwe mahormone, zvinokosha kufunga kuti Ritmos circadianos pakati muviri, uyewo kushanda adrenal cortex. The dose nerimwe murwere anosarudzwa nomumwe.

The daily kuwanda kemikari yakanakisisa kubatwa mangwanani (kazhinji zano kunwa dose yose iri zvinobva 6 kusvika 8 o'clock mangwanani, kana mumwe kuti kuiganhura vachiita muzvikamu zviviri - pa 8 uye 12 maawa). dosing kwakadaro kuchengetwa gadziriro dzose hormone. Hakuna kusara uye "metipred".

Mahwendefa vanobviswa zvakananga munguva kudya kana shure. In vana, dose akatsunga maererano nezera uye muviri uremu.

Normal kugadzirira anobva 4 kusvika 50 MG pazuva. A wakakwirira dose (1 g) unoratidzwa varwere systemic connective zvinyama zvirwere akanyanyisa nekuomarara. Cherechedzai chipiwe kugadzwa zvinodhaka kuti nhengo nokuisazve wacho, kana ezvokunambira kunze kwomuviri waamai muchangosangana.

nemishonga

Zvakakodzera chipimo chemushonga zvinodhaka uye kuchengetwa zvose chiremba mirayiridzo kana kutora divi Marwadzo vari chinenge kumbobvira kutanga. Zvisinei, tinofanira kuyeuka kuti kana zvaipesana kugamuchira zvinhu zvingamuka zvakakomba zvakakwana ezvinhu. Izvo kungaguma pakushandisa mushonga uyu?

"Metipred" zvikurukuru ine kunambwa ari kwemakemikari anobudiswa hurongwa. Vanogona vasanyanye shuga kushivirira, Kugadzirwa urwere pakati Cushing, pabonde kukura kunonoka (apo rakavapa vana).

The zvomudumbu Hurongwa anogona kupindura kwokubatsira zvinodhaka kukura kuda kurutsa uye kurutsa, shanduko zvituru, pfungwa nomuviri zvemwana asati, urikanwi, kusvikira ropa uye perforation mudumbu rusvingo.

Zvazvakaita "metipred" kumwoyo kunoratidzwa sezvo arrhythmia, bradycardia, Kushatiswa nhengo mumwoyo kukundikana.

Tsinga rinowanzoshandiswa kuchengetwa deliriepodobnoe ezvinhu psychosis kukura, paranoia, kushaya hope uye vertigo.

Contraindications

Kana uchifanira kushandisa mushonga uyu? "Metipred" rinogona kushandiswa chete kwenguva pfupi. Nokuti yakareba kugamuchira contraindications nyora anowedzera chaizvo.

Zvokungwarira vaishandisa mushonga panguva zvomudumbu zvirwere turakiti zvakadai nemaronda, gastritis, maronda colitis, gastrointestinal kuvhiya.

Vazhinji zvinotapukira zvinosanganisirwawo pamazita hama contraindications, sezvo zvisingazivikanwe sei muviri ikasakendenga yachengetwa kemikari zvinodhaka. Chimwe zvimiso inorambidza kushandisa mahormone ndiko zvavo immunosuppressive kushanda.

Havashandisi mushonga kuti chirwere cheshuga, kufutisa.

Vana nevakadzi vane pamuviri vari muboka Mhedziso contraindications pakushandisa "metipred". Ipa zvinoita chete zvakaitika apo pane chinokosha ngozi kuupenyu.

Aiita zvimwe zvinodhaka

Zvinozivikanwa kuti zvinodhaka zvakawanda zvinogona kuwedzera, kuderedza kana neutralize migumisiro vamwe mishonga. Sei zvaanoita "metipred" pamwe concomitant kwokubatsira zvimwe zvinodhaka?

Kushandisa mushonga uyu hepatic enzayemu inducers akazoita wevasungwa kuti basa fuma muropa (anotowedzera kumukomborera muviri wayo).

Kana mishonga mushonga "metipred" pamwe diuretics yekudyidzana kunowedzera ngozi mwoyo nokukundikana uye hypokalemia.

"Metipred" kupomba kurapa, apo kugadzwa cardiac glycosides pamusoro hurongwa kunowedzera ngozi yokubatwa ventricular arrhythmia.

Usashandisa pamwe methylprednisolone uye Anti-coagulants, sezvo achiipa ari kuchirapa mugumisiro yokupedzisira.

Kutora zvinodhaka nedoro uye nonsteroidal vamiririri kunowedzera mukana gastrointestinal maronda.

"Metipred" akazoita Kushanda insulin yakakodzera uye zvinodhaka antihypertensive.

Mirayiridzo yokushandisa

In chii chipimo chemushonga siyana zvinogona kuvapo "metipred"? Sei itungamirirwe nomumwe wavo? Ngatitarisei nyaya idzi.

"Metipred" (Mahwendefa) pamwe Nachiremba siyana munyoro zvirwere uyewo pasina contraindications kuti ingestion.

Lyophilisate - rinokosha zvinodhaka, inova upfu kuti dilution uye intravenous yaitonga. Rinoshandiswa zvikuru kwazvo nzira chirwere, uyewo zvashata rubatsiro.

The zvichiguma Kugadzirisa inokurudzirwa kushandiswa pakarepo. Kana uchida kuramba kwekanguva, saka zvinofanira kuitwa panguva tembiricha 15 kusvika 20 inegumi. At yakaderera haagoni kuchengeta mushonga yakabikwa mamwe mazuva.

Zvokuzvidzivirira murwere inokurudzirwa kushandisa yakafanana antacids (kudzivirira mucosa).

Asati kushandiswa, mushonga vanofanira nguva dzose bvunza chiremba maererano chipimo chemushonga uye kakawanda kutarisirwa kwaro.

"Metipred" pakurapa mbereko

In Gynecology, uyewo mune dzimwe minda zvokurapa, uyewo akashandisa "metipred". Chii mishonga iyi ushandiswe?

Kushandiswa chikuru zvinodhaka - immunosuppression ezvokunambira kunze kwomuviri waamai muchangosangana.

ECO - nzira, musimboti riri govera mukadzi zai, nembeu pawo bvunzo chubhu munhurume dzisingaoneki uye Implementation of zvichiguma zygote mudumbu.

"Metipred" IVF kunoratidzwa vamwe immunosuppression. Zvinokurudzirwa kushandisa mazuva mashoma pashure kuchinjwa ari zygote kupinda uterine mhango. Izvi zvinoitwa kuitira kubvisa mukana kurambwa nomuviri, "vatorwa chinhu".

In yakanaka Mugumisiro kunoitika mudumbu muchibereko ari endometrium, placenta inotungamirwa uye fetus kukura embryo.

"Metipred" IVF anoratidzwa vakadzi vose. In pamberi contraindications kuti kushandiswa kwayo kunofanira kusiyiwa ezvokunambira kunze kwomuviri waamai muchangosangana.

Zvimwe zvirwere munhukadzi dzokubereka nadzo kungada kugadzwa mahormone. "Metipred" iri Gynecology neapo kushandiswa kurapa leukoplakia uye mamwe maitiro anogumbura.

Mabatirwo systemic zvirwere

Under izvi ezvinhu, kazhinji kuita anonzi kufamba kweropa mishonga. Musimboti kurapwa nzira iri sezvinotevera: munguva pfupi nguva (kazhinji 1-2 mazuva) murwere chinotarisirwa imwe dose ravakwa guru, uye ipapo kwevhiki dzinoverengeka (zvichienderana kwokuomerwa uye Chirwere) - Nokuraramisa dose kurapwa.

Somuenzaniso, mune mishonga ine systemic vasculitis, zano iri sezvinotevera: kugadzirira "metipred" tanga raitongwa panguva dose anosvika 1000 MG, ipapo murwere zvaitambidzwa kutsigira kurapa (80-100 MG).

zano iri rakashandiswa nokuda kwayo yakakwirira kunyatsoshanda.

Pakatanga makuru mishonga kunoita "kushushikana" chirwere uye kukura vanonzi metabolic kukundikana. Panyaya iyi, njodzi muviri nyore kudzorera chakaipa siyana pane avo pasina zvakadaro simba zvikuru. Uyewo, nokuda huru mishonga zvinoita tunodzivisa ruzhinji masero masoja.

Pulse mushonga inogona vaisanganisa pamwe cytostatics kuti vabudirire zvikuru raidudzwa immunosuppressive kushanda.

The kukosha kwokushandisa zvinodhaka

mishonga iyi haigoni kungova kutenga panguva chezvinodhaka. chiremba chete anogona kupa mushonga kuti "metipred". Zvairatidza kuva rinokosha (semuenzaniso, systemic anogumbura zvirwere). Chete iyi, asi mishonga achakupa zvakakodzera mishonga yacho.

Chimwe chinoratidza mushonga ndechokuti kana kushandiswa yakareba zvinogoneka muropa kana chitarisiko ucharwadziwa.

Zvinoita nyaya uko refu uye pamatunhu mishonga raitongwa "metipred". In zvakafanana, ipapo mwoyo pachake mahormone neve adrenal mumasero. Muchiitiko ichi haafaniri pakarepo abrogate zvinodhaka. It akakurudzira kwenguva refu kuti zvishoma nezvishoma kuderedza dose. Chete mumamiriro ezvinhu akadaro romuzvarirwo kemikari usage inogona kudzorerwa.