Cushing kuti Syndrome: Zviratidzo, nechirwere, Treatment

Cushing kuti chirwere rinowanikwa kana kuwedzera huwandu glucocorticoids mu ari adrenal cortex. The chirwere Inonyanya kubata vakadzi. The inonyanya kukonzera zvirwere kunosimudzirwa kugadzirwa pituitary ACTH (adrenocorticotropic kemikari), hunobata basa adrenal cortex uye inotungamirira vawedzere kwevari mahormone. Kazhinji chaizvo kusunungurwa adrenocorticotropic kemikari kukonzerwa bundu iri pituitary, uye mune zvimwe zviitiko, bundu kune dzimwe nhengo. The chirwere angatanga kana kugamuchira yakakwirira mishonga ine steroids ine cortisone kana nevanhu zviri murwiyo iro rine ACTH (raiwanzoshandiswa kuderedza zvirwere basa iri nhengo kuisirwa).

Cushing kuti Syndrome: Zviratidzo

General utano, uye vakadzi sei zviratidzo chirwere. Common zviratidzo chirwere ichi vari:

• nokukurumidza kufuta. The kuwedzera mafuta deposits chiso uye kunyanya chokumusoro chikamu shure;
• striae (tatamuka mavanga) pamusoro mudumbu, chipfuva, maoko, uye nezvidya;
• kupwanywa, rive dete chedebwe;
• havaratidzi achiporesa nemaronda;
• kuramba tichishanda apore pashure chakasimba zvirwere;
• simba, nekuneta;
• kufunganya, kushaya hope;
• kunyanya emotionality;
• nomusoro;
• kurasikirwa ndangariro nekugona;
• vakadzi - nokunonoka kumwedzi;
• Shuga kusashivirira, chinoguma cheshuga;
• BP.

Cushing kuti Syndrome: kuongorora chirwere

The rokutanga chirwere chinogona kuitwa pachishandiswa zvinhu maitiro kuti chirwere. Nokuti kuongororwa zvakarurama kunoda zvakawanda kwazvo tsvakurudzo umo muchava kuziva zvinokonzera kuti Cushing wacho syndrome. Izvi kunoda weti bvunzo kuona padanho cortisone. Uyezve tsvakurudzo kunosanganisira kuedza murwere kushandisa deksametanozonovogo bvunzo umo murwere inoshandisa mukati 2 c. dexamethasone, uye pashure 9 maawa ari pasi nokuyerwa cortisol ari plasma.

Kuziva chikonzero, izvo zvinogona kukonzera Cushing kuti urwere, ACTH pamwero kuyerwa. Saka, yakakwirira kwevari kemikari zvingaratidza adrenal dysfunction, uye yakakwirira chaizvo - pamusoro pituitary zvirwere.

Cushing kuti Syndrome: Treatment

Rakajairika uye inobudirira pakurapa chirwere ichi ane kusarudza transsphenoidal prostatectomy. Kana zvidzidzo kuwanako chaiyo nzvimbo yacho pituitary bundu, akaita zvokuvhiyiwa kupindira. Nzira iyi haigoni kushandiswa kana murwere ari kwazvo chirwere kana vari somatic zvokurwara.

Chimwe nzira kurapwa ndiko kuparadzwa adrenal mumasero. Nokusuma zvinodhaka skleroziriruyuschih zvinogoneka kubvisa hyperplastic fuma. The nzira rinoitwa nokushandisa Ultrasound uye computed tomography nzira.

Panewo nzira nokuda pakurapa Cushing kuti chirwere sezvo hwepurotoni mishonga. Nzira iri rinoshandiswa kana yakavimbika nzira pituitary anomera vasingadaro. Zvinogonekawo kurapa ichi mishonga chirwere nzira. Panyaya iyi, nzira inoshandiswa kudzvinyirira ACTH kugadzirwa. Vaberekawo symptomatic kurapa zvainanga pakurapa netsinga, chirwere cheshuga, osteoporosis. Mune zvimwe zviitiko, nzira nemwaranzi mushonga ingashandiswa. Cushing kuti chirwere kunosanganisira kugamuchira kunyaradza zvinodhaka, bisphosphonates, mavhitaminzi nezvimwe zvinodhaka. The chirwere nokururamisira zvakanaka kurapwa uye mharuro yokurapa zviratidzo zvishoma nezvishoma kunyangarika.