The islet pakati Langerhans pakati rwatata. Antibodies kuti masero nezviduku ose Langerhans

Mumwe islet pamusoro Langerhans anoita chaizvo, zvinokosha chaizvo kuti yose muviri. Its chikuru basa - ndiko kudzora zviri makabhohaidhiretsi muropa.

History yakawanikwa

The islet pamusoro Langerhans itange kurondedzerwa muna 1869. Akawana idzodzo zvinokosha izvi raiva rwatata (kunyanya muswe chikamu chayo), aiva mudzidzi muduku Rudolfa Virhova - Paul Langerhans. Ndiye wokutanga aongororwe maikorosikopu sumbu masero, izvo avo morphological Murongerwo yakasiyana nemamwe pancreatic tishu.

Zvakanga dzakwidzwa kuwanikwa kuti Langerhans kuIslets kwemakemikari anobudiswa basa rinoitwa. Zvakawanikwa izvi zvinoitwa KP Ulezko-Stroganov. Muna 1889 kwaiva nguva yekutanga kubatana pakati pokukundwa nezviduku ose Langerhans uye kugadzira chirwere cheshuga.

Chii chingava islet pamusoro Langerhans?

Pari, mamiriro ichi kwave kudzidza zvakanaka zvakakwana. Zvino inozivikanwa kuti inotungamirwa iyi zvakasiyana-siyana. Panguva iyoyo, tinoziva zvinotevera ndivo:

• Alpha masero;
• masero Beta;
• Delta masero;
• p-masero;
• epsilon masero.

Zviri kuburikidza kusiyana iyi muzvitokisi zvavo islet mabasa ose mabasa manzi kwavari.

Alpha-masero

Miti iyi anenge 15-20% ekudzidza islet. Chinangwa chikuru chemusha Arifa-masero ari kugadzirwa glucagon. kemikari ichi ane lipid hunhu uye pachangu jekiseni antagonist. Pandakasunungurwa, glucagon kutungamirirwa chiropa, apo kunyorera zvakananga receptors, izvozvo inodzora shuga kugadzirwa nenzira glycogen Kuparara.

masero Beta

KuIslets of Langerhans dzehorokodzwa ndivo rakajairika. Ivo pamusana anenge 65-80% yose inowanwa. Zvinonzi ikozvino yakasimbiswa kuti dzinonyanya kushanda kutanga chimwe chezvinhu zvinokosha mahormone - jekiseni. fuma Uku antagonist pamusoro glucagon. Zvinokurudzira activation kuti glycogen inotungamirwa nekuchengeta nawo chiropa uye tsandanyama. Somugumisiro izvi ndiko kuderera yakawanda shuga muropa.

Delta masero

KuIslets of Langerhans pakati rwatata uyu mhando regai kuitika kazhinji. Ndivo 2-10 chete% yose inowanwa. Zvino avo dzichipfekeka zvinhu vari kuzivikanwa. It Vakawana kuti masero aya synthesize somatostatin. Zvaiitwa pakugadzira vanoshingaira fuma iri kudzvinyirira chizvarwa somatotropin, somatotropin uye thyrotropin-kusunungura kemikari. Kureva kuti anoita zvakananga pamusoro hypothalamus uye Anterior pituitary.

PP-masero

islet nerimwe Langerhans of mhando rinobatanidzwa elaboration pakati pancreatic polypeptide. Kusvikira pakuguma kwayo basa asina kudzidza. Pari, iye ndiye ane ehupfumi kuti kudzvanyirira kugadzirwa pancreatic muto. Uyezve, zvainoita kunobatsira kuzorora anotsvedzerera tsandanyama yacho nduru dundira. Mumakore achangopfuura zvikuru nokushingaira kudzidza kutsamira pane padanho kweShanduro fuma kubva paumbwe nyanyisa anomera. Zvakaguma akawana kuti kukura kwavo wakawedzera pamwero pancreatic polypeptide. Saka izvi pakugadzira kushingaira fuma inogona aionekwa chiratidzo chakanaka nyanyisa mapundu ose rwatata.

Epsilon masero

nezviduku ava Langerhans ndivo kupfuura kakawanda. Of zvachose kuverenga asingasviki 1%. The chikuru basa masero dzakadaro kubereka hormone inonzi ghrelin. rinoita zvinhu izvi ane vakawanda mashandiro, asi zvikuru kudzidza kwayo ndangariro zvazvinoita kudya.

About zvokurwara kuIslets of Langerhans

Kukunda zvivako izvi akaoma pane muviri zvikuru Migumisiro. Kuri kuti pave antibodies kuIslets of Langerhans, nhamba rokupedzisira iri zvishoma nezvishoma shoma. Rokukunda vanopfuura 90% of masero zvinoderedza kugadzirwa jekiseni kuti achitsoropodza yakaderera chechetere. Zvinoguma kukura kwezvirwere ngozi zvakadai zvakadai cheshuga. Antibodies kuti islet masero kazhinji dzinoitika varwere mudiki.

Serious kukuvadzwa vemo masero vanokwanisa gormonprodutsiiruyuschih chikonzero kuzvimba rwatata - pfungwa nomuviri zvemwana asati.

How kuponesa islet masero?

Zvichaita kuti vatarisire rwatata yose yose. Chekutanga zvose zvakafanira kusiya eChechi doro. Chokwadi kuti vane pamusoro rwatata yose zvokudya kupfuura inokanganisa. Kana mazhinji doro muvanhu kunoitika uye mberi pfungwa nomuviri zvemwana asati, izvo pakupedzisira zvinogona kutungamirira kuvhunduka islet masero.

Kunze doro zvakakwana kunambwa rwatata ane yakawanda zvokudya zvakawanda mafuta mhuka. Panyaya iyi, mamiriro ezvinhu chichange zvinowedzerwa panyaya pamberi mutambo murwere nokuti havana kudya chinhu kwenguva refu.

Kuri kuti pancreatic zvinyama nechekare ane chirwere kushoma, zvinokosha kuona nyanzvi - chiremba kana gastroenterologist. Information unyanzvi vanachiremba kugadza ndaisagona yawapiwa, izvo zvinogona yekudyidzana kunetesa kukura Kumwe kuchinja kunotanga. Hereinafter ichaitwa Ultrasound rwatata pagore, iyo rinoitwa akabatana nedzimwe nhengo dzose abdominal mhango. Uyezve, zvinokosha kutora nokukanganisika kuongorora ropa pamusoro rayo zviri amylase.

Kuti tizive kutanga chisingaperi pfungwa nomuviri zvemwana asati, kuwedzera murabhoritari uye richishanda zvidzidzo, kuchabatsira kiriniki. The chikuru chiratidzo chirwere ichi ndicho chakaita marwadzo ari kuruboshwe repamusoro quadrant. Uyezve, iyi ine zoster marwadzo hunhu uye kunoitika kakawanda pashure pokutora yakawanda zvokudya zvakawanda mafuta mhuka. Mukuwedzera, murwere mushure zvokudya kungava hanya kuramba manzwiro waziya mudumbu. Zviratidzo zvose izvi vari kusiya zvakasimba zvakakwana kana kuderedza kwokuomerwa yaro varwere kugamuchira mishonga ine pancreatin. Pakati pavo, zvikuru dzakakurumbira zvinodhaka vacho "Creon", "mezim" uye "Pancreatin". Kana muine kuzvimba mu rwatata rinenge nani uye vanoramba zvachose kubva doro. Chokwadi ndechokuti kunyange chiduku anogona kutowedzera chirwere muitiro, saka zvikuru hurikukanganisa muviri.