Motilium: kurayira

Motilium kusunungurwa Mahwendefa aiendeswa yakayamwa kana slurry fomu. The kushingaira wemafuta zvinodhaka ndiko domperidone iyo inesungano antiemetic centrally kuita ichivharira dopamine receptors muuropi.

Motilium (mushandisi sezvakaratidzwa) ane antiemetic ehupfumi nekuti domperidone kuchititadzisa dopamine kugadzirwa, vamwe antipsychotics. Zvisinei, zvinoshingaira fuma iri havaratidzi woga kuburikidza neropa-uropi chipingamupinyi pashure pokugamuchira anenge hapana divi Marwadzo zvinochengetwa. Cherechedza kuti Motilium zvinoita pituitary shwanu, akadai prolactin.

Pakurapa domperidone ichiwedzerwa panguva dantralnyh uye duodenal sunga, wakakurumidza gastric Kuburitswa mu, wakawedzera sphincter kufurirwa, riri yepazasi chikamu zvomudumbu wemuTesitamende vanhu hwakanaka. The mushonga hakuna zvainoita pagadzirwe gastric muto.

The pharmacokinetic zvechadenga

Mushure kutora mushonga usina chawadya "Motilium" (gwaro hurukuro nezvazvo) yava kunyura kubva nemudumbu. Kunonyanyisa wevasungwa zvinodhaka munyika plasma kunotemwa pashure maminitsi 60.

Domperidone inokurudzirwa kutora usati wadya, sezvo netsvakurudzo kuti zvinodhaka izvi, vakatanga pashure zvokudya wefodya kubva ura masvingo kwenguva.

Motilium, zvairatidza kuti kushandiswa

The mushonga ari ushandiswe:

- pamwe fufune, izvo pamwe nokunzwa kuzara, bloating, marwadzo, belching, flatulence, kuda kurutsa, kurutsa, chirungurira;

- svoto uye kurutsa dzichipfekeka makemikari, kutapuriranwa etiology yomuka pashure radiotherapy, zvinodhaka kurapa kana kudya zvirwere;

- svoto uye kurutsa kunokonzerwa dopamine-agonist zvinodhaka vanenge Parkinson nehosha kana kugamuchira (L-dopa Somuenzaniso, uye bromocriptine).

Motilium, Chinyorwa dosing

Kana fufune ari chirwere chimiro vakuru nevana vane zera mashanu, kugadza 10 MG zvinodhaka. Idya pamberi kudya kwemaminitsi anenge 30. Chiremba ringavakurudzira, kana zvichikodzera, vanogamuchira Motilium pamberi yokurara. Kufadza daily dose vana pasi makore 12 (5 years) chinotarisirwa mune imwe mari 2.4 MG domperidone pa 1 kg muviri uremu, asi izvozvo hazvifaniri kupfuudza 80 MG.

Vachiona kushaya maturo, chiremba anogona kaviri chete dose kuti Motilium nevakura uye vana vaya zvasvika makore 12. Asi chero zvakadaro hatifaniri kusapfuudza vaifanira zuva dose - 80 MG.

Motilium (mushandisi rinoratidza zvakajeka ichi), anogadzirwa muchimiro mapiritsi kuti yakayamwa, ari chete akaronga kushandiswa vakuru nevana vane muviri uremu kg 35. In Pediatrics, kushandisa mishonga kuturika Motilium®.

Nokuti varwere renal kukundikana inokurudzirwa kuwedzera penguva pakati mishonga mbiri zvinodhaka. Nokuti kuti itsvo rinowanika kuzochinja domperidone chete 1%, hapana chikonzero kugadzirisa chitsama chete kwokubatsira kuti mushonga varwere vane itsvo. Kana apiwa kugadzwa chiremba anofanira kufunga kwokuomerwa renal kukundikana, mune chaiyo zviitiko kungada dose rutapudzo.

Contraindications kuti mushonga "Motilium"

The mushonga hakufaniri kutorwa nomuromo:

- pamwe zvemaziso intestinal mhingaidzo kana perforation inotokonya gastric motility kune ngozi;

- gastro-intestinal ropa;

- yakatarwa prolactin-secreting pituitary bundu (prolaktinome);

- vachitsigira ketoconazole preoral;

- Vana vaduku pane 5 makore contraindicated ari pahwendefa chimiro, Zvinokurudzirwa "Motilium" iri muchimiro kuturika;

- ane sema paakasangana nomumwe zvinoumba kugadzirira.

Sezvo unorema kubva zvinodhaka Rinobva kuburikidza chiropa, chinofanira kupiwa nokungwarira pavarwere vane domperidone kukwana chiropa chaitika.