LDH - chii? Zvikonzero kuwedzera LDH

mushonga Modern haamiri vachiri, uye zuva richikura. mumwe muzvizhinji kuti assays anoshandiswa rokuongorora zvirwere zvakasiyana-siyana. Avhareji munhu zvakaoma kunzwisisa zvose mazita avo. Tora somuenzaniso, LDH. Chii, mumwe nomumwe munzira haazivi, asi nzira iyi tsvakurudzo, vanachiremba kushandisa kakawanda. Chii chirwere chinogona chirwere kushandisa LDH kuongorora kupfuura anotarisana yakawedzerwa kana yadzikira dhigiri ropa. Rega kuongorora.

Chii LDH

Tinofanira kutanga kunzwisisa zvakavanzwa pasi vatorwa, pakutanga aitarire, imwe Acronym LDH. Lactate - chaiyo enzayemu, izvo zvinokosha dzinotsanagura oxidation kuti shuga uye kugadzirwa lactic acid. muviri mukuru kuti fuma iyi haisi kukwanisa kuunganidza. Nokuda dzinongoitika urongwa, zviri kuparadzwa uye yabudiswa. Zvisinei, pane zvimwe zvirwere kuti vari pedyo yakakwirira kwevari LDH muropa inozivikanwa. Izvi zvinoitika muna zviitiko apo ukama zvinyama kana masero mumuviri. Ndokusaka LDH - rinokosha chaizvo zvechinguvana nako aite Diagnostics.

mhando LDH

Chii, isu kare afunga, asi kudiwa kujekesa zvimwe zviri enzayemu ichi. Sezvaunoziva, ane mhando shanu, izvo vakasiyana mumwe chete muchitokisi mamiriro. Uyezve, mumwe nomumwe pakubhadhara izvi zviri kusimbiswa yoga miviri.

Nadzurudzo ane enzayemu rinonzi lactate dehydrogenase isoenzymes. Saka, Munokudzwa:

• LDH 1 - koshesa ari uropi uye mwoyo tsandanyama.
• LDH 2 - nayo ane masero eropa (erythrocytes, maplatelet), uye chiropa.
• LDH 3 - zviri skeletal tsandanyama, mu rwatata uye thyroid omumuviri, uyewo nyama nhengo dzakadai nomumapapu, chirwatata uye adrenal mumasero.
• LDH 4 - chinokurira saizvozvo zvomukati sezvo LDH 3, uye kuwedzera, mukono utachiona masero, placenta, chiropa, uye granulocytes.
• LDG 5 - dzakawanda isoenzyme ichi inowanikwa munyama pamusoro skeletal tsandanyama uye chiropa, asi vamwe pane kuti, zviri aripo chete zvomukati, uye LDH 4.

wokuyera

Saka, isu afunga chii LDH. Ndozvakajairwa pamusoro enzayemu iri yakasiyana vakuru nevana uyewo varume nevakadzi. Chokutanga, chii zviratidzi vanoonekwa nevamwe vana.

• Pazuva upenyu enzayemu wevasungwa wokutanga kunofanira kuva 22.1 mkkat / l.
• Mazuva mana akatevera unomutswa kusvikira pachiyero 28.9.
• Kubva vhiki mwedzi pazera uye ashaye LDH matanhatu. Rate ndiyo 16.3 mkkat / l.
• Inotevera 6 Mwedzi mararamire inowedzera zvishoma zvakare, panguva ino kune chiratidzo 18.3.
• Pashure aurayiwe gore rimwe uye kusvika makore matatu LDH muvana vanofanira kuva 14.2 mkkat / l.
• Kubvira makore indices manomwe Vanhurume nevanhukadzi siyana vanotanga kusiyana. Boys pamwero romuzvarirwo vanofanira kuva 12.7 mkkat / L, uye nevasikana - 9,67.
• Pashure pemakore gumi nematatu pakati chakarurama enzayemu akatsiga pachiyero 11,4 vakomana nevarume vakuru. ichi zvazvingava zviri zvishoma ipfupi, uye hwose riri 7.27 mkkat / L pavasikana nevakadzi.

LDH ropa. Chii?

Sezvambotaurwa, chinhu chakanakisisa zvechinguvana kuti chirwere matambudziko akasiyana-siyana dzomuviri. Asi chii chinoumba nokukanganisika kuongorora LDH? nzira iyi ropa yekuedzwa, iyo unogona huwandu lactate muropa. Kana pane kudikanwa kuongorora zvakadaro?

zvairatidza kuti

LDH rinoitwa mu nyaya apo pane fungidziro kuti nhengo vakakuvadzwa kana hurongwa hwavo. It rinenge kukuvadzwa chinokurwadzai kurera enzayemu muropa. Izvi ndezvechokwadi kunyanya mwoyo rinenge uropi, bapu, itsvo, skeletal tsandanyama.

Kana uchifungidzira kuti melanoma uyewo kuitisa ropa lactate dehydrogenase. Zvinorevei? Chokwadi kuti ongororo iyi inoratidza metastasis ari nhengo uye node nodes. Izvi nzira dzepamusha melanoma haagoni kunzi chairo, asi anobvumira kuti kuongorora mamiriro murwere ari pakati postoperative nguva, uye kuona padariro bundu kukura. Uyezve, pane nyaya anobudirira enzayemu kurapa ropa kunodzikira, saka, zvechinguvana ichi chinoshandiswa kuziva simba ari kurapwa.

Kugadzirira hurukuro ongororo

Asati kuita pachisara murwere anofanira aigadzirira. Ungangove, chiremba wako achaita mazano kurega kutora zvimwe mishonga, sezvo vanogona kukanganisa rakarurama LDH zvabuda. Chii, hatina kutoziva. Asi zvinoreva chii haigoni kubatwa kwemazuva matatu asati ongororo? Izvi zvinosanganisira aspirin, dzokutindivadza, ascorbic asidhi (vhitamini C), mitromitsin, clofibrate, procainamide, fluorides. Unofanirawo kurega doro, nokuti unogona kuwedzera ufanane kudzidzwa enzayemu.

Sezvo kuongorora

Blood zvakabudiswa akanga kuitwa mutsinga akura ari mudanga maoko Via rinokosha tsono. Kuti kutora mashoko acho vana kana vacheche, shandisa Lancet. Kuwedzera mutsinga, chiremba anogona kutora ropa kubva divi rezasi renzeve, huru chigunwe kana chitsitsinho. Uise fenzi chinogadzirwa uye pashure nzira, hazvina rinoshandisirwa munhu kumanikidzwa bhandeji. Zvichitevera nzira zvingaitika marwadzo zviduku.

mimwe Ropa vakaiswa bvunzo chubhu kana maikorosikopu ondomoka. Murabhoritari, kuti vaiunganidza zvinhu yakaitika chaiyo centrifuge, kuburikidza icho serum iri dzinounzwa kwazviri. Saka, kuziva padanho enzayemu muropa.

On chii chinofanira kuva tsika isu vati kare. Huwandu enzayemu anogona zvose zvakawedzera kuva uye kuderedzwa. Chii chinogona kukonzera?

Zvikonzero chichiwedzera pamwero LDH

Kana pakuongororwa anoratidza kuwedzera LDH, zvakakodzera kutsvaka chikonzero chiitiko ichi. Yakakwirira pamwero ayo vati kuti paiva kukuvadzwa chero tishu. Kana zvabuda vanoratidza nokuwedzera uwandu vanopfuura mumwe isozyme uye zvakawanda, zvinoita zvingaratidza kuti pane vakawanda zvirwere zviri mumuviri. Zvinoitika kuti pakuongororwa anoratidza zvakawedzera pamwero zvose mhando mashanu LDH. Muchiitiko ichi tinogona kutaura vakawanda nhego kukundikana.

Zvisinei, nechirwere haigoni kuiswa, kunobva kungobva nenhanho LDH. A muedzo zvachinja nhamba isoenzymes ropa kunobatsira, asi, panzvimbo kunyatsotsanangura yake. Pasinei neizvi Nyanzvi kuziva izvo masimba kuteerera pakutanga, kana ichirova LDH. Zvikonzero angava sezvinotevera:

• Nevanga.
• Myocardial infarction. Panyaya iyi, mwero inogona kusimuka kwemaawa 36-55 mushure kurwisa. An uwandu vakawedzera kubva enzayemu hwaponeswa kwemazuva 3-10.
• Pulmonary infarction. Zviratidzo ake okutanga - ari kurwadziwa muchipfuva nzvimbo. Zvadaro, uye akamutsa kwevari imwe enzayemu.
• bowel infarction.
• Myocardial itsvo, pyelonephritis.
• Congestive mwoyo kutadza.
• Chiropa zvokurwara uyewo kuva chikonzero yakawedzera pamwero LDH. Zvinorevei? Chikuru uwandu enzayemu ichi kunowedzera cirrhosis, zvinyama kuchinja nokuda udhakwa, uyewo chakasimba nemavhairasi chiropa.
• Nekenza vanoitwa pamwe kuwedzera LDH pamwero.
• zvirwere ropa vanotsamwisa hemolysis.
• LDH ndiyo chiratidzo uye rikwanise pfungwa nomuviri zvemwana asati.
• Hypoxia, hypothermia, hyperthermia.
• Rwekenza yelymphoma.
• Mononucleosis, raikura somugumisiro chirwere.
• Nemavhairasi yomumuzongoza. Kuwedzera padanho LDH kunoratidza kuti pane encephalitis kukura.
• Dystrophy, tsandanyama atrophy, makuvaro dzavo.
• Zvinorwadza kuvhunduka.
• Makatsemuka uye mitswe.
• Multiple kutsva.
• Pfari.
• Chidhakwa kana marwadzo delirium.
• Eclampsia.
• Vamwe vakadzi vane pamuviri, yakakwirira kwevari LDH - hwandaiva mamiriro. Nokuti vamwe, vakadai kuongorora zvingaratidza yokuzviparadzanisa yacho placenta. Chero zvazvingava, kuwedzera mwero LDH - chikonzero kuona chiremba.

Sezvambotaurwa, kune anotoita mumwe kana kupfuura isoenzymes kuti LDH haagoni pachawo anoratidza mumwe kupfuura zvirwere. Zvakakosha kuita mamwe kuferefeta. Kunoda kuti tizive basa imwe isozyme. Ipapo chichava zvinobvira kutaura nezvedambudziko localization.

Somuenzaniso, mukuru siyana vave kuzivikanwa isoenzymes 4 ne5 LDH. Chii? Asi, paiva kurasikirwa tsandanyama rinenge kana chiropa. Asi kuona ichi, zvinokosha kuona dzichipfekeka miedzo muviri murwere.

Saka LDH munhu akaidza mugumisiro anogona kunzi chete akabatana nevamwe zvidzidzo. Zvinokoshawo kuti kuongorora simba uyu muitiro, sezvo richiita basa rinokosha mune Pakusarudza pathological kwendangariro.

Kwakaderedza pamwero LDH

Dzimwe nguva pakuongororwa aratidze kuderera padanho LDH muropa. Ichi chiitiko nokururamisira chisingawanzowaniki chinoratidza kuti nhengo iri kushingaira rinotsemuka kuti shuga uye anogamuchira kubva mairi simba nokuda masero, kazhinji tsandanyama.

Ungaderedza LDH uyewo zvinogoneka Gene kunotouraya. Pamwe chete vaviri adzo. Vanhu nechirwere rokutanga mhando, uchanzwira kuneta uye tsandanyama simba. Kunotouraya rechipiri mhando vasina zviratidzo. The kuderera LDH pamwero kunogonawo kukonzera kudya kuti ascorbic asidhi (vhitamini C).