"Zvigadzirwa" (mahwendefa kubva kumagetsi): mirayiridzo yekushandiswa, zvakafanana, kuongorora

Nzira yekushandisa sei mushonga we "Design"? Mirayiridzo yekushandisa chigadzirwa ichi ichagoverwa gare gare. Uyewo iwe uchadzidza nezvezvinhu zvipi zvinosanganiswa mukugadzirwa kwemishonga, mumhando ipi inobudiswa, ingave inogona kupiwa kuvana nevakadzi vane pamuviri.

Chimiro, chimiro, tsanangudzo yemishonga

Ndezvipi zvikamu izvo kugadzirira "Dizal" kunosanganisira? Matafura kubva kumagetsi, iyo mirayiridzo iyo yakaiswa mukati mekadhibhoti, ine bhuruu yebhuruu, biconvex uye fomu yakazara, uyewo kuverenga "LT" kune rimwe divi. Nhengo inoshanda yechirwere ichi inonzi desloratadine. Iyo inewo zvimwe zvinoshandiswa nenzira ye microcrystalline cellulose mannitol, gorosi pregelatinized starch, magnesium stearate uye talc.

Kana iri yekuvhara mafirimu emahwendefa, anosanganisira blue opadrai, macrogol uye indigo carmine dye.

Inofanirawo kuonekwa kuti mushonga uri mubvunzo unowanikwa nenzira yesirasi. Desloratadine inoshandawo seiri iyo inoshanda.

Pharmacology

Mishonga inonzi "Dizal" (mahwendefa kubva pamakumbo ose) anoshanda sei? Iyo murayiridzo, yakabatanidzwa pamushonga uyu, inoshuma kuti iyi ihosha antihistamine yenguva refu. Iro blocker ye peripheral histamine H1 receptors.

Nhengo inoshanda yemishonga iyi ndiyo inonyanya kushandiswa metabolite ye loratadine. Iyo inhibisa kupindurwa kweeergergic, kurega pro-inflammatory cytokines uye chemokines. Uyewo, izvi zvinopedza kugadzirwa kwe superoxide anions, chemotaxis nekubatanidzwa kweeosinophils.

Izvi zvakasununguka kumushonga zvinobatsira kudzivirira kusimbiswa uye kuderedza kugadzirisa kwehutano. Ichi chemishonga ine antiexudative uye antipruritic properties, inodzivirira kukura kwemafupa akasvibiswa, edema yematukisi uye inoderedza kupora kwema capillari.

Mapiritsi "Dizal", mutengo waro ucharatidzwa pasi apa, hauna simba pamusana pemaitiro emhando, uyewo hauna kuita sedative (kureva kuti, hausi kukonzera kurara) uye haikanganisi mupfungwa inotarisana nemunhu (kana achitora maitiro anorayirwa). Mukuwedzera, mushonga wacho hauna kutambanudza mutengo weQT pane ECG.

Kurapa kwechirwere ichi kunotanga mukati mehafu yeawa mushure mekudya uye kunopedza zuva rose.

Pharmacokinetics

Ndeapi ma pharmacokinetic mitsara inoita "Dizal" mishonga (allergy mapiritsi) ane? Iyo mirayiridzo inoti kana mushure mokutora mishonga iyo inoshandiswa inoshandiswa yakanyatsopindira kubva pamigwagwa yekudya. Mu plasma yeropa, inogadzirirwa mushure mehafu yeawa, uye iyo yakawanda inotarisa inosvika mushure maawa anenge matatu.

Kukurukurirana ne plasma mapuroteni emishonga iyi 85-87%, uye hafu yehupenyu inenge maawa makumi mana. Desloratadine yakaderedzwa kuburikidza nemubumbo (pasi pe7%) uye muyero (pasi pe2%).

Zviratidzo zvekushandiswa

Kubva pane zvinotarisana nechiso ichi chinodhaka chinobatsira zvikuru. Inoshandiswa kwete kwete kuderedza chete, asiwo kubvisa zviratidzo zvinotevera:

• Urticaria (rash and skinch skin);
• Allergic rhinitis (rhinorrhea, kupopota, kutema kwedenga, kusanganisa kwemazamu, kubwinya uye kuchenesa kwemaziso, kuchenesa mumhino, kuchema).

Contraindications for use

Kubva pane zvemazuva ose panguva yekuzvitakura, kugadzirira "Dizal" kunorambidzwa. Uyewo, hazvirevi kunwisa nekuyamwisa uye muvana vari pasi pemakore gumi nemaviri (kuchengeteka uye kubudirira hazvina kugadziriswa). Usashandise mishonga iyi uye nekuwedzera kwekunzwa kwemurwere kune yakashanda kana zvimwe zvinoshandiswa zvechirwere.

Nekuchenjerera kwakanyanya, mahwendefa e "Diazal" anorayirwa kuti ave nehutachiona hwakakundikana.

Chirwere ichi "Dizal" (mahwendefa kubva kumagetsi): murayiridzo

Sarudza mapiritsi akadaro anofanira kungoita nyanzvi yepamusoro. Kurwisa (urticaria, pruritus, rash, etc.) muvana vane makore gumi nemaviri uye vakuru vanorapwa zvakafanana. Maererano nemirayiridzo, mahwendefa anofanira kutorwa nemuromo, pasinei nekudya. Muyero wemishonga iyi inotsanangurwa nachiremba uye, sekutonga, ndeye 5 mg kamwe pazuva (kureva, 1 piritsi rimwe nerimwe pazuva).

Zvakaipa Kuchinja

Kubva pamatambudziko evana vanopfuura makore gumi nemaviri, chirwere che "DysAul" chinofanira kutarisirwa nekuchenjerera zvakanyanya. Izvi zvinokonzerwa nekuti iyi mishonga inogona kukonzera nhamba yakawanda yemigumisiro.

Kakawanda kune vamwe, kutarisa kwakadaro kusingadikanwi sekuwedzera kuneta, kuora musoro kwemanheru nekuoma kwezwi mumcosa inowanikwa mune varwere.

Pakati pekucherechedza, mamwe mimwe migumisiro yakawanikwa zvakare. Fungidzira ivo iye zvino:

• Kubva pamutemo weshe zvinogona kuonekwa kugona, mupfungwa yepfungwa, kusava nehanya uye kushaya hope.
• Kubva kune rumwe rutivi rwegumbo rekudya, kurwadziwa kwepamuviri, chirwere, chirwere chinoputika, dyspepsia uye kurutsa zvinowanikwa.
• Pane chikamu cheB bile duct uye chiropa, kune zvinhu zvakadai sekuwedzera kwemajeri ebilirubin, kuwedzerwa kwebasa remakemikari ane simba uye hepatitis.
• Tachycardia uye palpitations zvinokanganisa kubva mumoyo nemidziyo yevarwere.
• Kubva bony uye muscular system, myalgia inoonekwa.

Inofanirawo kuonekwa kuti pamusana pekutora mishonga iri mubvunzo, varwere vanogona kunge vane zvinetso zvepfungwa mumamiriro ekutsvaga uye kugadzirisa zvinokonzerwa nehutachiona, anaphylaxis, kupisa, angioedema uye urticaria.

Zviratidzo zvekudarika

Kubvira pamakumbo evana kune makore anopfuura gumi nemaviri, pamwe chete nevakuru, chirwere chinonzi "Dyshal" chinofanira kutorwa mumutengo unorayirwa.

Paunotora mushonga wacho muhotera yakakwirira (somuenzaniso, nguva 9, iyo 45 mg), hapana zviratidzo zvekuita zviratidzo. Zvisinei, kugona kunogona kuitika.

Sekurapa, inofanirwa kushambidza dumbu uye kutora marara. Inofanirawo kucherechedza kuti desloratadine haisi yakanyanyiswa ne hemodialysis.

Kubatana nemimwe mishonga

Kubatana kwechirwere ichi "Dasal" nemimwe mishonga haina kuonekwa (kusanganisira "Erythromycin" uye "Ketoconazole"). Uye zvakare inofanira kunzi kuti desloratadine haisimudzi kukanganisa kweethanol mukati memutambo wenheyo.

Mazano Anokosha

Kurwisana (urticaria, pruritus, rash, etc.) kune vanhu vane chirwere chisina kunaka chekushaya simba kunofanira kutarisirwa nekuchenjerera.

Maererano neongororo, mushonga we "Dasal" haubatsiri kutungamirirwa kwemurwere nemotokari. Asi iwe unofanira kugara uchifunga nezvazvo zvisingawanzoiti vamwe vanhu vanokura hope. Munyaya iyi, kutarisirwa kunokosha kunofanira kutorwa paunenge uchifambisa uye uchishanda nemichina yakaoma.

Mari nezviyero zvemishonga yemishonga

Kusiyana nezvimwe zvinorwisa antiallergic, mutengo wechirwere "Dizal" hausi wepamusoro. Iwe unogona kutenga iyi mishonga ye 200-350 rubles (mahwendefa gumi nemakumi matatu zvichienderana).

Kana ari mifananidzo yezvinodhaka mubvunzo, kune zvakawanda zvavo. Ngatitumirei iwo: "Isheestin", "Blogger-3", "Erius", "Desloratadine", "Elisei", Desloratadine-Teva, Ezlor, Desloratadine Canon, Nalorius, Desloratadine-Kudyanya.

Kuongorora nezve antiallergic drug

Chirwere "Chigadzirwa" - mishonga isingabatsiri kurwisa mishonga, izvo zvinosara nezvakawanda zvose zvisina kunaka uye zvakanaka. Vakawanda varwere vanotaura kuti mishonga iyi inobata zvakanaka nebasa racho. Iyo inokurumidza uye inobudirira inopedza zvose zviratidzo zvehutano hunoita, zvichivandudza zvikuru hukama hwomurwere.

Vanhu vakatora mapiritsi "Dizal", vanopupura kuti zviri nyore chaizvo kuzvishandisa. Kusiyana nedzimwe mishonga, mushonga uyu unokwana kutora kamwechete pazuva uye unogona kukanganwa nezvemagetsi.

Pane mhinduro dzakaipa pamusoro pemutara uyu. Varwere vakawanda havagoni kuitora, nokuti vanobva varatidzira kuratidzira kwegogiramu. Vanachiremba vakadaro vanorwara vanopa mishonga yakachengeteka.