Zvairatidza Dzokushandisa "Metformin": mirayiridzo inofambiswa

"Metformin" chinhu chinokosha chokushandisa vanhu chirwere cheshuga mellitus. "Metformin Richter" zvairatidza kuti kushandiswa kuri akakodzera varwere vakawanda vane chirwere cheshuga, kunobatsira kuderedza ropa shuga yomuropa, nokudaro tiine zvakakodzera nenhanho carbohydrate muviri, nokudaro dzekugonesa kunaka upenyu, sezvinoratidzwa vakawanda akanaka mhinduro wevarwere.

Pharmacodynamics uye Pharmacokinetics

"Metformin" DZEMUNHU DZINODZORA chirongwa gluconeogenesis ari chiropa uye zvinova chipingamupinyi kuzova kubva ura mumaoko nemuviri shuga. Saka pane enhancement pamusoro peripheral shuga cleavage uye anowedzera chiropa rinenge aikanganiswa jekiseni. azvaiitwa hadzina achiperekedzwa gipoglemicheskimi siyana mumiririri asingadi kukanganisa kwomuzvarirwo kugadzirwa Beta mumasero rwatata jekiseni, kusiyana nevamwe zvinodhaka analogues "Metformin".

Zvairatidza uremu mishonga akazviratidza nokuda kukwanisa kwayo kudzikamisa kana kunyange kuderedza murwere muviri uremu.

Apinza "Metformin" kubva nemudumbu vari kutanga kupinda basa fuma uye chinobudirira zviito zvinodhaka kunotangira pashure pemaawa 2-2.5. A chinokosha ndechokuti zvinoreva kutopedza unlinkability kuti mapuroteni eplasma.

"Metformin" anogona kuunganidza mu netsvo uye chiropa, mate shwanu, tsandanyama dzomuviri. Hwakaratidzwa anenge chose itsvo pashure maawa 9-12 pashure kutarisira. Kana renal murwere basa kwakakanganiswa rinoreva anogona -wedzera mumuviri kwenguva refu.

Zvairatidza uye contraindications

Zvairatidza Dzokushandisa "Metformin" sezvinotevera:

• Chirwere cheshuga mellitus mhando 2, vakapfuura pasina mafungiro kuti ketoacidosis, izvo zvinokosha chaizvo kuti chirwere cheshuga vakafuta.
• Akabatana jekiseni iri mhando 2 cheshuga, kufutisa chinopunyaira, ichiteverwa yechipiri insulin irambe.

Pasinei mukuru kunyatsoshanda zvinodhaka, pane contraindications pakushandisa "Metformin":

• Ketoacidosis mu cheshuga predkomatoznoe nehurumende kana pakoma.
• Atadze kushanda zvakanaka etsvo.
• Chenjera zvirwere, zvichiita kuti chimiro itsvo dysfunction - utachiona, kupera mvura mumuviri zvakaoma. manyoka kana kurutsa, fivha, zvirwere kufema ezvinhu, hypoxia.
• Chenjera uye chisingaperi zvirwere, zvichiita kuti chimiro zvinyama hypoxia - cardiac kana kufema kukundikana, chenjera myocardial infarction.
• Inini kuvhiya kupindira, pashure iyo yakarongwa kubaya jekiseni.
• Chiropa dysfunction.
• Chenjera panyaya iyi chepfu, chisingaperi chidhakwa.
• Pregnancy.
• Achiyamwa.
• Idiosyncrasy.

chipimo chemushonga

Chipimo chemushonga "Metformin" akatsunga inobva ropa shuga kugutsikana uye basa chiremba neimwe murwere nomumwe. Kazhinji kutangira chipimo chemushonga neeSultan kubva 0.5 1 g / zuva. (1-2 Mahwendefa), uye zvadaro, inobva shuga pamwero pashure pemazuva 10-15 kugamuchirwa zvinobvira incremental kuwedzera uwandu husingakuvadzi.

Kwerunyararo dose "Metformin" ndiyo 1.5-2.0 g / zuva. (3-4 Mahwendefa), uye kufadza chipimo chemushonga - 3.0 g / zuva. kana 6 Mahwendefa. Varwere vari kukwegura kumusoro dose - kwete kupfuura 1.0 g / zuva. (2 Mahwendefa).

Zvairatidza Dzokushandisa "Metformin" uye uchapupu wevarwere vanoti mushonga inofanira kunwiwa panguva kudya kana pakarepo pashure pacho, kunwa mvura pachena. The daily dose inokurudzirwa kuti ive 2-3 mishonga yose zuva.

Zviito ovhadhozi

Ovhadhozi kungaita kuti lactic acidosis, izvo zvava kuda kufa.

Lactic acidosis kunoratidzwa anotevera zviratidzo:

• Dzungu achiperekedzwa svoto uye kurutsa.
• Manyoka.
• The unopinza kuderera tembiricha muviri.
• nokukurumidza kufema.
• Sharp kurwadziwa ari tsandanyama, dumbu.
• Kurasikirwa pfungwa uye kutanga pakoma.

Apo Kanenge nyoro zviratidzo lactic acidosis hwobva kurega kutora zvinodhaka "Metformin" kutora matanho muchipatara.

Inonyatsobudirira kuchirapa basa kana hemodialysis riri lactic acidosis, uye inobudirira vabatwe nomumwe zviratidzo.

Aiita zvimwe zvinodhaka

The mushonga "Metformin" zvairatidza yokushandisa iyo haabatanidzi concomitant kushandiswa kwezvinodhaka nevamwe zvinodhaka hazvigoni kushandiswa pamwe dinazolom nokuda hyperglycemia okupedzisira chaizvoizvo. Kana zvakakodzera, kurapwa dinazolom vanoda dose kuchinja "Metformin", izvo zvinofanira kuchengeta chiremba.

"Metformin" Reception vanofanira kurega zvachose chipimo chemushonga kuchinja akabatana zvinotevera zvinodhaka:

• "Chlorpromazine".
• Neuroleptics.
• Oral nhumbu, thyroid hormone, thiazide uye loop diuretics.
• "Epinephrine".
• "Cimetidine".

Uyewo, kana akaratidza kuti kushandisa "Metformin" zvakakodzera kusiya zvachose doro yaunodya, zvikasadaro, kutonga nezvinooneka mhinduro wevarwere, kuti muviri chaizvoizvo ari yekudyidzana ipfupi.

"Metformin": inofambiswa kana zvinoshandiswa uremu

mumwe chete kuchirapa kushanda haringorevi kutsanangurwa kushandiswa zvinodhaka "Metformin". Zvairatidza kuti kushandiswa, uye wongororo uchapupu mano akadai:

• Zvinoderedza yomuropa.
• Rutapudzo rwokuzvarwa jekiseni, iyo inosvitsa zvinoderedza kudya.
• Ichivharira paumbwe carbohydrate huni chiropa.
• Kuderedza padanho kuitwa pamusoro makabhohaidhiretsi kupinda muviri nezvokudya.

Kushandisa "Metformin" kuitira kuderedza uremu zvinonzwisiswa kuti yaro huru nerevane ndiko kusika ezvinhu umo zvekushandisa mafuta deposits pane tsandanyama tishu. Nokuti inobudirira uye hazvikuvadzi muviri uremu, maererano akawanda inofambiswa pamusoro kugadzirira zvose kuvarwere uye vanachiremba vanofanira asike wakakodzera ezvinhu:

• Yakarashwa rinotapira uye furawa, uyewo kurerukirwa zvokudya (noodles, bota, mashed mbatatisi).
• Yokuderedza yaunodya kuti macalorie.
• Active uye muviri nguva dzose.

Kana tichishandisa "Metformin" slimming chipimo chemushonga tisiye 500 MG / zuva, uye kudya vanofanira kupiwa asati kwemasikati uye chisvusvuro. Reviews nokushivirira kugadzirira anoratidza zvakakwana kubudirira kana kudonhedzera yokufutisa, asi kushandisa "Metformin" chaiyo nokuti zvinangwa izvi hazvibvumirwi pasina zano chiremba uye dietitian.

nemishonga

Pasinei yakafara zvairatidza kuti kushandiswa, "metformin" kungaita nekuratidzwa mamwe mamiriro zviratidzo zvechirwere nemudumbu, kunobva kurutivi Migumisiro zvinodhaka:

• Kurutsa uye svoto.
• Murombo Nzara kana ayo vasipo.
• Flatulence, manyoka, abdominal marwadzo.

Kazhinji Zviratidzo izvi pakutanga kurapwa uye, mune pfungwa wevarwere inonyangarika voga.

Zvikuru chakakomba nemishonga nezvimwe gadziriro:

• B12 vhitamini kwokusakwana, uye lactic acidosis.
• Megaloblastic kupererwa neropa.
• Yomuropa.
• Skin rashes sechinhu sema kuita.

Mirayiridzo Special kuti kushandiswa, uye anoshivirira uchapupu

Kufanana mumwe mushonga ine contraindications ayo uye zvairatidza kuti kushandiswa, "Metformin" kunyatsoitwa kuti chipimo chemushonga uye nguva okutambirwa.

Zvikurukuru munguva nokugamuchirwa vanofanira kugara akuteerere itsvo chinosara idzo kushoma pakati kaviri pagore, uyewo kuratidzwa myalgia vane kuona zviri lactate mu plasma. Uyezve, mwedzi mitanhatu ose zvinofanira kuongororwa mukati serum creatinine, kunyanya munguva wevarwere.

Kana kugamuchira "Metformin" akabatana sulfonylureas zvakakosha kuramba kuongorora padanho shuga muropa.

Kana hosha yacho genitourinary ezvinhu, kana bronchopulmonary zvirwere hwobva nyaya chiremba wako.

The mushonga asingadi kukanganisa kukwanisa kutyaira motokari uye asingauyi kupindira mubasa iri zvigadziriswe.

Tikafunga "Metformin" nevamwe zvinodhaka hypoglycemic kungaita kuti pave hypoglycemic ezvinhu, dzinoratidzwa ndangariro chirwere, izvo rambidza tichigadzirisa motokari uye vaiita mamwe mabasa nengozi uye zvinoda zvikuru kutarisirwa uye kuita.

Munguva kurapwa iri zvachose wairambidza doro uye zvinodhaka zvine panyaya iyi.

Maererano wongororo zvinodhaka "Metformin" pasinei zhinji inotyisa provleniya nemishonga kuitika vachiri mashoma chaizvo, kana zvishoma. Uye kuti vanoda kutaura kunyanya inotapira, apo kunwa mushonga zvinobvira kuuya bande keke kana chinonhuwira, kunyange Kazhinji.

Uyewo mune pakudzokorora patsintov manotsi chirwere cheshuga uye yakawedzerwa mukana wokuva pamuviri apo pakugamuchira "Metformin" kuti kwete chete kunobatsira kubvisa chirwere, asi kuwana vakaroorana vafare.