The mushonga "Betaxolol": mirayiridzo kushandiswa, description, akafanana uye wongororo

Anosiya nokuti maziso "Betaxolol" (mirayiridzo Chinyorwa classifies pavo zvokusarudza Beta-blockers refu chiito) zvinoshandiswa ophthalmic tsika, uye mahwendefa zvinonzi nevakawanda kushandiswa mukurapa dzakasiyana-siyana zvemwoyo.

Release chimiro uye sezvamunoita

Rinoreva "Betaxolol" anogadzirwa chimiro mahwendefa uye madonhwe ziso. Mumwe chena piritsi zvemapuranga aine firimu unhani ine 20 MG ose vanoshingaira wemafuta betaxolol hydrochloride. Sezvo mamwe zvimwe ndiwo: yavaibvisa carboxymethylstarch, magnesium stearate, microcrystalline cellulose, lactose monohydrate, aerosil. Kuronga goko unotora polyvinyl doro, chena Opadry 2, macrogol, talc, titanium dioxide.

Ndokurongedza zvidimbu 10 aruminiyamu Maronda akasiyana mapiritsi "Betaxolol." Instruction kushandiswa iri akanyudzwa mukati makadhibhokisi bhokisi.

Muziso donhwe pa 1 Rine mamiririta nhoroondo 5.6 MG ose vanoshingaira wemafuta betaxolol hydrochloride. Secondary zvinhu rinoumbwa zvinodhaka ndivo: yavaibvisa hydroxide, benzethonium chloride, hydrochloric acid, dihydrate, edetate disodium, yavaibvisa chloride, mvura. Izvi yellowish segirazi fuma. The mhinduro yakanga akanyudzwa nehombodo-IV (5 kana 10 Rine mamiririta). More pauri uye dropper chubhu ari chipimo chemushonga pamusoro 1.5-5 Rine mamiririta. Mune kabhodhi bhokisi ndokuisa nemirayiridzo mupudzi dropper.

The pasherefu upenyu uye sherefu

Pasherufu upenyu zvinodhaka (mahwendefa uye madonhwe ziso) makore matatu. Mushure kuzarura bhotoro samadonhwe zvinogona kuchengetwa hakuna kupfuura mazuva makumi maviri navasere.

Pharmacokinetics

The pharmacological zviito zvinodhaka kunoratidzwa Beta-kusarudza adrenoblokiruyuschey, antianginal, antihypertensive, antiarrhythmic, antiglaucoma dzidziso.

Blocks beta1-adrenergic receptors ane sympathomimetic basa, uye runopfuura diki Kamudzira pakudzikamisa ehupfumi. Akazoita susceptibility kuti munyama kuti catecholamines, nechepakati DZEMUNHU DZINODZORA nomunhu, izvozvo chinomisa secretion kuti renin. It kunoderedza kwemwoyo uye anoderedza myocardial okisijeni manwiro (antianginal ehupfumi). Blocks kuitika ectopic foci ari atria, AV-siyana.

Mugumisiro wacho akacherechedza pashure maawa maviri pashure ingestion, uye kufadza zvinodhaka wevasungwa mumuviri ndee mumaawa 3-4 uye rinovapo kwemaawa 12-24 pa chenguva dzose kushandisa zvinodhaka kwemazuva 7-14. Inochengetedza pamusoro BP kuwedzera panguva yechiitwa uye mupfungwa mupfungwa.

The Mabatirwo cheBP riri nokuda zvinoderedza rworuboshwe ventricular guru uye kuwedzera ayo contractile chaitika. About 75% varwere nounyoro kuti zvive nomwero neBP kuita zvakanaka kune monotherapy yakadaro. Refu kushandiswa kwezvinodhaka asingadi kukanganisa ratios ose lipid muviri uye excretion kuti yavaibvisa. In vanhu vane asima uye bronchitis mune chirwere muchimiro hazvideredzi zvemapapu chaitika.

Eye anosiya "Betaxolol" (mirayiridzo Chinyorwa anoti pamusoro pokudzora kwomudzimu zvinodhaka kuti kuderedza intraocular kumanikidzwa Akaroromesawo intraocular mvura) regai kukonzera marwadzo akadai zuva-upofu, miosis, spasm akkommodasie, uye madzerere.

Kuvhiringidzwa zvasvika pashure hafu yeawa pashure chikumbiro, kufadza wevasungwa vakachengeta pashure maawa maviri uye rinovapo kwemaawa gumi.

Zvairatidza yokushandisa

Anokurudzirwa kuongororwa kuti "neBP" Inopera Achiviruka myocardial ischaemia (angina), akathisia, kushatiriswa neuroleptics, "Betaxolol" mapiritsi.

Eyedrops (Murayiridzo Chinyorwa zano rokuti kubvunza chiremba vasati kuvashandisa) kuratidzwa panguva chirwere rakavhurika akachinjikana yemaziso, intraocular neBP. Vanachiremba varayire mushonga pashure Laser trabeculoplasty. Kushandiswa nguva refu antihypertensive kurapa, kudiwa izvo akamuka nokuda ophthalmic kuvhiya kupindira.

zvokurapa contraindications

Pasinei nekusimba kubudirira "Betaxolol" chinodhaka (Drug Usage akanyeverwa mukanyatsochengeta kuchengeta dose waakaudzwa nachiremba uye kwete kuzvidzora medicate), kushandiswa kwayo ane zvimwe contraindications. Izvi zvinosanganisira hypersensitivity kuti basa pakuderedza zvinodhaka, uye mamwe zvinhu zvayo sezvamunoita. Paro hazvitenderwi apo fikisruyutsya sinus bradycardia (asingasviki 45-50 u. / Min) uye sinus kurwara. Haukwanisi kushandisa mushonga panguva AV blockade II-III dhigirii, hypotension. Contraindicated "Betaxolol" vanhu vane cardiogenic kuvhunduka pavarwere vane zvikuru mwoyo nokukundikana uye zvakakomba obstructive kufema kukundikana.

Zvokungwarira zvinofanira kutorwa pavarwere vane chirwere nemabayo, varwere kusagadzikana angina, mumwe kubatwa kuti bradycardia. Kungwarira kunofanira kunyengedza AV-chinogumbura I dhigirii, peripheral kweropa kukundikana. Anofanira kuva varwere kungwarira kunyanya cheshuga, yomuropa, chiropa uye chirwere cheitsvo, hyperthyroidism. Doctors vanofanira kuongorora kuti kurapwa pavarwere vane tsandanyama simba vakwegura uye vana.

Panguva pamuviri uye lactation zvinodhaka wokukundwa, kana kuti zvinotarisirwa kubatsira kuti mai kudarika yavanababa zvingakanganisa azvarwa. Panguva kurapwa ngaanyarare uchiyamwisa.

"Betaxolol": mirayiridzo kushandiswa

Price, ongororo, mudonzvo - ava zvinhu zvakanaka mishonga anokonzera varwere zvakare uye zvakare kusarudza izvozvo.

Mahwendefa vanofanira nedoro mangwanani. NeBP dragees tora kamwe, achitanga dose 10 MG. Kana pashure pavhiki zvinozoita haina kuwana, kubva dose yakanga yawedzera kusvika 20 Rine mamiririta. Kana vaitarisira mugumisiro akatadza kamwe zvakare kusvika, shure kwemazuva 7-14, kuwedzera dose kusvika 40 MG.

Varwere havachanyatsogoni itsvo basa, dialysis, uyewo vakwegura vanofanira kushandisa mushonga mune mari 5 MG kamwe zuva. Kana zvakakodzera, kuti dose anogona ngazviwedzerwe ose mazuva 14 5 MG. It rinokurudzira kusapfuudza kunonyanyisa dose - 20 Rine mamiririta "Betaxolol" gadziriro - mirayiridzo kushandiswa.

Abstract rinokurudzira kushandisa Madonhwe ziso yemaziso. Instillation yaifanira zvakasimba muna ari conjunctival zai. A chete dose ndomumwe donhwe. chiitiko ichi kunoitika kaviri pazuva. Mumazana mwedzi kurapwa, chiremba vanofanira kuongorora murwere intraocular kumanikidzwa.

nemishonga

Kutaura kuti kungaguma nematambudziko zviitiko kushanda "Betaxolol" gadziriro kudzidziswa Chinyorwa. Mutengo zvinodhaka riri gutsaruzhinji, izvo zvinoita nyore zvikamu zvose vokuparidzira (80 kwiza. Nokuti 5 Rine mamiririta chinu uye 370 rubles. Nokuti mapiritsi 30).

Panguva kurapwa "Betaxolol" pangava chisingaperi kuneta uye nemusoro, dzungu, hope, kushaya hope, kuzvidya mwoyo. Akaderedza wevasungwa, kurota zvinotyisa, aone zvinhu zvisipo, kukanganwa, neuralgia, vestibular zvirwere.

Vamwe varwere vave kuona uye kusabetsera kutyora weti, marwadzo ari pazamu (vakadzi), prostatitis, fibrocystic zamu kuchinja. Paiva fufune, manyoka, muromo yakaoma, kuda kurutsa, kurutsa, kupatira, abdominal marwadzo. The mushonga dzimwe nguva kwakakanganisa kunokanganisa pazvirwere zvemapapu chirwere, dyspnea, kuchikonzera muchipfuva marwadzo, pharyngitis, rhinitis, sinusitis. Wakaiswa bronchospasm, dyspnea, kufema kukundikana.

Pakati marwadzo yave kuzivikanwa sezvinotevera: bradycardia, hypotension, myocardial infarction, mwoyo kukundikana, leukocytosis, thrombocytopenia purpura nezvimwe zvirwere. Zvakakwana kashoma arthralgia, tendonitis, myalgias.

Zvinogona mapundu, alopecia, neutachiona, eczema, shanduko uremu muviri, erythema, hypothermia, exacerbation pamusoro psoriasis, hypertrichosis, prurigo.

Kushandiswa ziso anodonhedza anokwanisa kutsamwisa lacrimation, maziso akaoma, madzerere, photophobia, keratitis, erythema, yokumwe muviri manzwiro ari ziso, corneal nehanya, anisocoria uye photophobia.

Zvokungwarira

Apo Betaxolol zvinodhaka kurapa (mirayiridzo application vaiudzwa kuti chipimo chemushonga uye nzira kurapwa) kazhinji nokuchinja murabhoritari parameters. Zvingava zvakanaka venhema maitiro ari dope, vakawedzera titers ose antinuclear antibodies uye t. D.

Ovhadhozi "Betaxolol" chinodhaka

Mirayiridzo dzokushandisa (analogs zvakafanana rinoita fuma uye kunodarowo) rinokurudzira zvakasimba chipimo chemushonga. Zvikasadaro, ungasangana zvisingafadzi zviratidzo zvakadai:

• dzungu;
• kutyora kumwoyo;
• bronchospasm;
• richikwidibira ropa shuga;
• mhasuro chinyamunhari chinorwadza;
• richaparara.

Panyaya iyi dzekare kurapwa basa sezvinotevera:

• gastric lavage;
• Kushandisa absorbent zvinhu;
• symptomatic kurapa - intravenous atropine 1-2 MG kuti Beta-agonists, sedatives vamiririri, cardiac zvinodhaka;
• transvenous pacing (basa chete kana zvashata).

Personal zvokungwarira

Zvipatara yaifanira pasi zvokurapa achitarisirwa. In marapirwo havagoni kuona kutanga kwekupwanyiwa hyperthyroidism uye yomuropa. Izvi ndizvo varwere vane chirwere cheshuga. Kwakaderedza compensatory dzinotsanagura mwoyo uye ropa midziyo. Haukwanisi kushandisa mushonga pamberi kuvhiya.

Kushandisa zvinodhaka vakwegura dzose kunowedzera ngozi hypothermia, kusagadzikana ezvinhu mupfungwa, kukanganisika zvemwoyo basa. Varwere hosha yeitsvo uye chiropa inofanira kuva pasi chiremba ndiye aitungamirira basa mazuva mana okutanga. Kana sema kare anogona kuwedzera hypersensitivity uye kuderedza kuchirapa mugumisiro adrenaline.

Panguva kushandiswa zvinodhaka hakubvumidzwi kutora doro. Newewo havagoni payakakurudzirwa kumisa kurapa uye vanofanira kuzviita zvishoma nezvishoma, Akaroromesawo dose mumakore kwemavhiki maviri. Rinorayira vatyairi kungwarira pakushandisa mishonga "Betaxolol" mirayiridzo Chinyorwa.

Price, analogues zvinodhaka

Kana mushonga hauna akaswedera, chiremba anogona nguva dzose kupa analoginen, izvo kazhinji akasiyana chete mutengo. Saka, mapiritsi uye anosiya "Betaxolol" mutengo pamusoro 80-370 rubles. By analogues zvemahwendefa dzinosanganisira:

• "Betacam" (Cyprus), inenge 300 rubles kuti mahwendefa 20.
• "Lokren" (France), mutengo mahwendefa 28 - 600-700 rubles, uye nokuda 56 mapiritsi - 1000-1200 rubles.

Eye anosiya pamwe betaxolol hydrochloride vanoshingaira fuma inogona kutsiviwa zvinotevera zvinodhaka:

• "Betalmik EU" (Slovakia), 160-200 rubles.
• "Betoptik" (Belgium, United States), vanenge 300 rubles.
• "Betoptik C" (Belgium, USA), mukati 300 rubles.
• "Betoftan" (Romania), 200 rubles.
• "Ksonef" (India), 180 rubles.
• "Ksonef BC" (India), vanenge 150 rubles.
• "Optibetol" (Poland).

Anoti pamusoro kubudirira kurapa neBP zvinodhaka "Betaxolol" mirayiridzo Chinyorwa. Price, Wongororo (analogues anodhura, asi zvimwechetezvo pamusoro muviri) - ruzivo zvose izvi anoratidzwa munyaya.

Views wevarwere

It rinorumbidza kushandiswa "Betaxolol" donhwe ophthalmic kurapa kudzidziswa Chinyorwa. Price (Wongororo vanoti uyu ndiwo mumwe zvikomborero zvinodhaka) yakaderera, uye saka vanogona kutenga chero chikonzero kurapwa. Varwere vakawanda inoratidza kubvumirawo zvimwe samadonhwe ziso rakanaka. Vanoti kuti havasi kukonzera marwadzo. Mugumisiro kunoonekwa pakupera vhiki yokutanga.

Achibatsirwa mapiritsi vanhu kudzora BP. The mushonga kunobatsira kuderedza mutoro pamwoyo, anovandudza mukuru ezvinhu varwere. Vamwe kunetseka chirwere kugayiwa kwacho mumazuva kutora mapiritsi mangwanani. Kune vanhu vari uyo zvinodhaka kwakaita sema mapundu uye akatsvuka paganda. Mumwe akaona svoto uye zvikuru arrhythmia.

Vazhinji wongororo pamusoro zvakanaka nemishonga, varwere vakanga inogutswa mushonga uyu.