Product "Levodopa": mirayiridzo kushandiswa, description, akafanana, analogs uye wongororo

Chii chinodhaka "Levodopa"? Mirayiridzo yokushandisa, mutengo, wongororo pamusoro mushonga ichakurukurwa zvishoma mberi. Uchadzidzawo pamusoro zvaanoda mishonga iyi, kana akanga chero nenjodzi uye contraindications, umo zvinoumba richiwanikwa kutengeswa, iyo Rinowanikwawo ayo akafanana, uye zvichingodaro.

The sezvamunoita, chimiro, tsananguro

Izvo zvinoriumba chine mushonga "Levodopa"? Mirayiridzo yokushandisa chinoratidza kuti kushingaira wemafuta zvinodhaka ndiko levodopa. In pakutengeswa zviri muchimiro dzeraundi spigot Mahwendefa chena ruvara, mumapepa ari gandiwa muchitokisi uye makadhibhokisi mabhokisi, ukuwo.

Nheyo kushanda ane medicament

zvinodhaka "Levodopa" sei kushanda? Mirayiridzo yokushandisa, wongororo akashuma kuti ichi mubatanidzwa antiparkinsonian mumiririri. It ndehwokuti kubvisa Rigidity, hypokinesia, tremor, drooling uye dysphagia.

Mumuviri, kuita chikamu mishonga iri kutendeukira dopamine (CNS), nokudaro vanoumba yokushomeka yacho chinhu.

Dopamine kuti kunoitika muna peripheral munyama, inoratidza hapana Anti-Parkinson anokonzerwa levodopa. Izvi imhaka yokuti hazvina zvinopfuura nechepakati tsinga uye ndiye kukonzera nenjodzi zvinodhaka.

Yokuderedza dose yezviri fuma iri muviri womunhu basa medicament akabatana FIs peripheral dopa-decarboxylase. nzira iyi kunobatsira kuderedza marwadzo kutora mapiritsi.

Pharmacokinetics

zvikuru sei mishonga wefodya 'Levodopa "? Instructions pamusoro pokushandisa inoti pashure kuwana mushonga mumuviri riri zvikuru nokukurumidza woga kubva ura.

Absorção de Água yezviri fuma anenge 20-30%. In ichi muviri chaizvoizvo akanga aona pashure pamusoro 3 h.

Food yaunodya (kusanganisira zvimwe zvokudya) zvakananga kunokanganisa Absorção de Água zvinodhaka.

The mushonga rinoita, nokudaro zvichiumba metabolites akawanda. Excretion yezviri fuma kunoitika kuburikidza itsvo, uye kubudikidza ura.

zvairatidza

Under chii ezvinhu varwere ushandiswe mushonga "Levodopa"? Mirayiridzo yokushandisa maererano zvinotevera zvairatidza:

• postencephalitic chirwere kuti unowanikwa cerebrovascular zvirwere kana chepfu kudhaka;
• Parkinson urwere, uyezve, yakanga kunokonzerwa nokushandisa antipsychotic zvinodhaka;
• chirwere chinonzi Parkinson.

Contraindications

Kana pane contraindications mu "L-dopa" chinodhaka? Mirayiridzo dzokushandisa inoshuma kuti mishonga iyi chinorambidzwa kutora zvinotevera nyaya:

• hypersensitivity kuna zvinoriumba izvozvo;
• pamwe Mao FIs;
• panguva yepamuviri uye panguva kuyamwisa mwana;
• varwere pasi pemakore 18.

With hanya zvikuru mushonga inogona yakatarwa panguva:

• emphysema;
• pamberi zvemapapu chirwere, mwoyo chirwere, chiropa uye kwemakemikari anobudiswa maitiro uye pangagara;
• Árbol asima;
• Kuratidza psychosis;
• melanoma (kusanganisira nhoroondo);
• angled-kuvhara yemaziso;
• yokudzokorora. pfari (nokugwinha);
• rakavhurika-angled yemaziso, kunoitika muna chisingaperi chimiro;
• itsvo uye chiropa kutadza;
• myocardial infarction (nhoroondo), uyewo nzira-siyana arrhythmias;
• duodenal urikanwi uye dumbu;
• CNS kuratidzwa kudzvinyirira;
• mwoyo mutinhimira vachivavhiringidza.

The mushonga ndiye "L-dopa": mirayiridzo kushandiswa

Description of zvinodhaka yave kukurukurwa pamusoro. Sezvo inofanira kuva?

Maererano mirayiridzo, mushonga chinobviswa nomuromo. The chipimo chemushonga iri kuwedzera zvishoma nezvishoma kubva zvishoma kusvika vaifanira (kuchitsamira pamunhu murwere).

Akatanga kurapwa ane dose pamusoro 0.25-1 d mari iyi rakakamurwa migove mitatu. The chipimo chemushonga iri kuwedzera zvishoma nezvishoma kusvika 0,125-0,75 d Itai izvozvo panguva zvakaenzana nguva (semuenzaniso, mazuva matatu), kufunga munhu murwere, kusvikira nguva apo optimum mugumisiro chichachengetwa kubva mishonga.

The kunonyanyisa dose pazuva haafaniri kupfuudza magiramu masere.

Mishonga chero zvazvingava, regai kukanzura nehasha. Regai kuushandisa zvishoma nezvishoma.

nenjodzi

Ko divi zvinokonzerwa zvinodhaka "Levodopa"? Mirayiridzo Dzokushandisa rinoti munyika akapoteredza kugamuchirwa kwayo panguva munhu anogona kuona dzimwe nenjodzi chokuita nokushanda zvose hurongwa muviri:

• Kumwoyo: mwoyo palpitations, arrhythmia, kuvhiringidza kumanikidzwa, orthostatic siyana, syncope, uye zvichingodaro.
• Zvomudumbu turakiti: manyoka, kurutsa, dyspepsia, kudya kupatira, shanduko kuravira, muromo yakaoma, ropa kubva nemudumbu.

Zvinofanira kucherechedzwa kuti dziripowo divi chinja kukanganisa mukushanda hematopoiesis, Urinary, kufema, uye huta hurongwa. Kazhinji Varwere kugamuchira zvinodhaka ichi neutachiona kuitika, kuchinja murabhoritari parameters uye pamamiriro migumisiro iri paganda.

Zviitiko ovhadhozi (zviratidzo, kurapwa)

In tikashandisa yakakwirira mishonga wakaratidza chinokosha enhancement kuti nemishonga. ezvinhu akadaro zvinoda kurapwa muchimiro lavage, murwere vakawanda mamiriro richiona uye kushanda kwomwoyo. Kana zvakakodzera, ubudise antiarrhythmic kurapa.

zvinodhaka kwavatori

Mawa kugamuchira uye hanya rekugadzirira "ditilina" Beta-agonists, uye vamiririri dziri varongerwa inhalation yokutindivadza, anowedzera mukana wokuti arrhythmias zvomwoyo.

Bioavailability "Levodopa" anogona kuderedza tricyclic antidepressants.

Tikafunga zvinodhaka ne "thioxanthenes," "Diazepam" antipsychotic "Phenytoin" M-holinoblokatorami "clonidine", "Difenilbutilpiperidinom" "Papaverine", "Clozapine", "phenothiazine" "pyridoxine" uye "reserpine" kakawanda kunoderedza yayo antiparkinsonian kushanda.

Lithium Formulations kuwedzera ndingangokuvara panowanikwa dyskinesias uye fungidziro, uye "methyldopa" medicament kunowedzera divi zvavaifunga.

Tikafunga Mao FIs uye "Levodopa" unotungamirira havachanyatsogoni kutenderera. Panyaya iyi, chinguva pakati mishonga mishonga izvi zvinofanira kuva mazuva anenge 14.

Nemuumbi zvinoderedza dzvinyiriro akaona mishonga uye vaiona "tubocurarine".

Drug "metoclopramide" kuwedzera bioavailability "Levodopa" kuwedzera gastric Kuburitswa mu. Izvi zvinogona kukanganisa nzira chirwere.

Dzinenge kurumbidza yokushandisa zvinodhaka

Zvaunofanira kuziva asati atora mahwendefa "Levodopa"? Mirayiridzo yokushandisa (mutengo pazasi) anoyambira pamusoro kutyisidzira utano nokuda chimbichimbi Kudzimwa ane medicament.

Muzviitiko apo hazvibviri kuti vadzivise rutapudzo pamusoro chipimo chemushonga kana kushaya mishonga inoda nguva dzose richiona kuti murwere ezvinhu.

Pamberi mushonga hauna varumbidzwa richapedza zvekudya akapfuma mapuroteni, sezvo akazoita absorbability yezviri fuma.

The kurapa kunoda kuramba richiona pamusoro siyana hurongwa, nhengo, uye ropa parameters.

Price uye analogues

The dzepedyo analogues "L-dopa" gadziriro zvinoreva wakadaro se "levodopa benserazide" uye "Levodopa Carbidopa". Mirayiridzo dzokushandisa inoshuma kuti zvinodhaka izvi vane zviratidzo, marwadzo, zvigadziriswe kuita uye contraindications. Musiyano chete pakati mari idzi sezvamunoita yavo.

Kwakadaro vanoshingaira zvinhu zvakadai carbidopa uye benserazide kuderedza kugadzirwa dopamine muna peripheral zvinyama, nokudaro vachiwedzera uwandu levodopa kupinda CNS.

Saka, unogona zvakachengeteka kuzivikanwa kuti nachiremba "Levodopa Carbidopa" uye "levodopa benserazide" (mirayiridzo kushandisa nzira idzi dziri midzi muna kavha) anobvisa mamwe kugamuchira FIs peripheral dopa-decarboxylase.

Kana mamwe vezera, ipapo yokuteverera zvinosanganisira mishonga yakadai se "Isik Meath", "Tremonorm", "Dopar 275", "Tidomet", "Duellin ',' Sinemet ',' Zimoks", "Sindopa", "Isik" "Lac". Vanofanira kuiganhura chiremba chete.

Mutengo "Levodopa" chinodhaka zvakakwirira zvikuru. In Pharmacies, unogona kutenga mishonga iyi mukati 1500-1850 rubles.

mishonga Reviews

Treatment chero chirwere yaifanira chete nechinangwa chiremba ane ruzivo. Uye chinonzi Parkinson hakuna anosara.

Varwere akatora zvinodhaka "Levodopa" iri kwayo yoga kungwara, uye hamuna zvakanaka kuchirapa kushanda. Saka kazhinji ichi medicament ongororo kunaka. Users akashuma kuti kunyange kushandiswa kwenguva yakareba mishonga chinozikamwa kunatsiridza zvinhu zvakanaka kuchengetwa.

Kana mishonga chinobviswa pasi kuongorora zano, iyo yakataurwa ane ruzivo nyanzvi iri kutevera nzira hosha, mishonga muitiro ndiyo inenge nguva kubudirira. Izvi imhaka yokuti yezviri chinodhaka inofanira kutorwa nenzira yakaoma chipimo chemushonga, izvo zvinoenderana murwere, zvinoitwa chirwere uye zvimwewo.

Varwere vari zvakasimba maererano kurapwa zvaiitwa, akashuma kuti zvinodhaka "Levodopa" riri chaizvo kubvisa zvinetso zvoutano.

Kutaura zvazviri, vakawanda vanotsutsumwa pamusoro kudhura kurapwa. Zvisinei, vanamazvikokota vanoti mutengo zvinodhaka izvi zvachose kwakarurama.