Ndezvipi maplatelet? Chii basa ravo mumuviri? Ndezvipi zvirwere maplatelet zvakawedzera

Maplatelet zvidiki non-yenyukireya vakaumba zvinhu ropa. Ivo vanobatanidzwa mune hemostasis (a kunzwisisa wanda zvainanga kumisa ropa uye yambiro). Maplatelet dzakaimomotera kana denderedzwa iri chimiro. The dhayamita muchitokisi iri pakati maviri nezvina microns.

Mumidziyo ropa, maplatelet vanosarudzirwa pamasvingo kana muropa. Kana yechipiri, masero vari izororere ezvinhu uye ane dhisiki chimiro. platelet activation chinowedzera kuchinja mhando dzavo: masero kuva sphericity uye yakananga chimiro protuberances (pseudopodia). Pachishandiswa azvaiitwa vanokwanisa zvinhu ropa kuomerera mumwe kana kuti parusvingo mudziyo une kukuvara. Fani iyi inonzi aggregation (akanamatira pamwe). Maplatelet, uyezve, ive nzvimbo kuti adhesion (cohesion), degranulation (kusunungurwa mukati), clot yokururamisa (kana kupatsanurwa akaderedza ropa clot zvakakwana kubva serum). On kwayo pamusoro, masero vanokwanisa kushivirira fibrinogen, imwe pfuma pakugadzira kushingaira (kweserotonin), anticoagulants, uye zvirwere zvivako (achiparadzira).

By adhesion uye platelet aggregation rinopa hemostasis mune diki-caliber midziyo (masero uchingounganidza pa nzvimbo kukuvara). Sezvo muviri coalescence mugadziriro adrenaline, thrombin, collagen, kweserotonin. With kutora chikamu thrombin ndiyo pezvakaitwa inotungamirwa (pseudopodia). Platelet pellets ane pakugwamba zvinhu (kweserotonin, peroxidase enzayemu platelet fibrinogen, adenosine diphosphate (ADP), kweserotonin, platelet-pacharo kukura chinhu, of Willebrand chinhu).

Panguva yokururamisa ropa clot kunoitika adhesion kuti fibrin filaments uye kusunungura trombostenina izvo rinopedza pamusoro pavo. Zvinoguma chisimbiso uye Kumonyorora shinda, nokudaro wezvamatongerwe chikuru thrombus.

Analysis ropa maplatelet kuti asarudze coagulation parameters. Achinzi zvinoitika Kuwanda 180-320 zviuru paminiti milliliter.

Kana maplatelet vachiwanda, ipapo thrombocytosis. ezvinhu akadaro angaratidza munhu chirwere ane hunhu, namamota, zvirwere ropa rwarisa. Thrombocytosis anogona kukonzera paumbwe ropa clots nenhumbi. Kana maplatelet vachiwanda, zvinokwanisika muviri tasara tisina mvura. ezvinhu akadaro kunogona kukonzerwa kurutsa, handitombokwanisi mvura yaunodya, chetsoka nyonganyonga.

Kuwanda maplatelet muropa dzingasiyana zvichienderana nenguva gore kana zuva. Achideredza sero kugutsikana inogona kuchengetwa ari kumwedzi kana pamuviri. Kazhinji maplatelet kwakawedzera pashure panyama nesimba.

Thrombocytosis munogona vakuru nevana. Kuwedzera platelet wevasungwa zvinogona chikuru kana yechipiri.

Vana thrombocytosis yakasimbiswa pashure achisiya vachiberekwa abnormalities.

Pakutanga yakawedzera maplatelet, yemanyorero panguva eritremii, chisingaperi myeloid neleukemia nezvimwe zvirwere ropa. Kuwedzera wevasungwa masero ropa vawadzane kumhanyisa kuti weboka aizotangira (megakaryocytes). Izvi ndizvo maitire akaipa kushanduka.

Secondary thrombocytosis dzakaonekwa zvirwere yomuka kuburikidza zvakawedzera kugadzirwa thrombopoietin (polypeptide kemikari).

Maplatelet anogona zviwedzerwe maronda colitis, pulmonary tibhii, RA articular maronda hunhu extrapulmonary tibhii, amyloidosis, osteomyelitis, chiropa cirrhosis nezvimwe chirwere anogumbura pathologies. Thrombocytosis kunoitika pazuva pakanyorwa pave nyanyisa namamota, hemorrhages, mamwe pakupona.