Metamizole

"Metamizole" rine yayo Anti-anogumbura, antipyretic uye marwadzo zvazviri nokuti kuti adzikatidza kwetunhu prostaglandins kubva arachidonic acid, kwakakanganiswa kuitisa marwadzo nomunhu kunowedzera kupisa kutapurirana uye anowedzera chikumbaridzo marwadzo nehanya.

Akati mushonga wefodya kwazvo kubva nemudumbu, uko hydrolyzed uye kushingaira metabolite vakaumba zvinenge hafu anosunga ropa mapurotini. Output zvinodhaka ari weti, sezvo panoparadzana mwoyo kupinda zamu mukaka.

"Metamizole" - mirayiridzo kushandiswa

The mushonga inoratidzwa kuti rutapudzo kurwadziwa chero kupi, kana neuralgia, kutemwa nomusoro, Sciatica uye myositis. Akabvumawo chikosoro, fivha rheumatism nezvimwe zvirwere.

Zvinokurudzirwa kutora "Metamizole" kubvira 250 kusvika 500 MG zvokuvataurira nomuromo, ichi chinofanira kuitwa 2-3 kanomwe pazuva. The daily dose haafaniri kupfuudza 3g, rimwe dose havafaniri kuva mukuru 1 giremu.

Vana vane makore makore 2-3 vanokurudzirwa kuita kusvika 50-100 MG zvinodhaka, makore mashanu -100-200mg, makore manomwe -200 MG uye kusvika makore 14 -250-300mg akati nzira, chipo chinogamuchirwa maererano audzwa iwayo.

Uyewo, "Metamizole yavaibvisa" rinogona kutorwa nomutsinga, intramuscularly, uye, panguva imwe chete nayo chinotarisirwa kusvikira katatu masikati, asi hapana anopfuura 2 magiramu pazuva, uye vana Zvinokurudzirwa kutora 0.1-0.2 Rine mamiririta por 10 kilogram muviri.

Contraindications

Hazvina varumbidzwa kutora mushonga uyu pamberi bronchospasm, mukuru aikanganiswa Metamizole, hematopoiesis zvirwere, nhaka hemolytic kupererwa neropa, renal kana hepatic insufficiency panguva yepamuviri uye lactation.

Possible nemishonga

Kugamuchira medicament "Metamizole" zvingakonzera mananara zvakadai interstitial nephritis, oliguria, weti anova tsvuku, proteinuria, anuria. Uyewo, neutachiona anogona kuitika sezvo conjunctivitis, urticaria, angioedema, uye dzimwe nguva anaphylactic kuvhunduka kunogona kuitika, bronchospastic urwere, Lyell syndrome. Leukopenia, kudukupiswa BP, agranulocytosis, thrombocytopenia, infiltrates panguva Kutarisirwa nzvimbo zvinogona kuva kurutivi nokuitika chezvinodhaka.

Matanho kutora "Metamizole yavaibvisa" chinodiwa panguva vakawanda kunotevera, kuvapo arterial hypotension, myocardial infarction, chisingaperi udhakwa uye kutanga kuvhunduka.

Kana uchida kushandisa zvinodhaka ichi kwenguva refu, zvakakodzera kudzora murwiyo uye mamiriro ezvinhu peripheral ropa.

At mawa womuchato chlorpromazine zvingamuka hyperthermia. "Metamizole 'haina nezvaaiitawo benzylpenicillin colloidal ropa Sevamiririri uye radiopaque zvinhu.

Chinangwa zvinodhaka iyi hormone nhumbu, dzisiri marwadzo analgesics, allopurinol uye tricyclic antidepressants zvingakonzera kunowedzera chepfu migumisiro.

Uyewo iripo "Metamizol-Sodium-Pitofenone Fenpiveriniya bromide" inova nzira zvabatanidzwa dzichipa spasmolytic uye marwadzo kushanda.

Kana ovhadhozi kunoitika kuda kurutsa, oliguria, chinyamunhari chinorwadza, gastralgia, BP rutapudzo, hypothermia, dyspnea, tachycardia, tinnitus, lightheadedness, hope, rikwanise agranulocytosis, kuoma kufema tsandanyama, havachanyatsogoni kuziva, Hemorrhagic syndrome.

Muzviitiko zvakadaro, gastric lavage rinoitwa kushandisa vachiongorora vakagamuchira sesaline laxatives uye nguva dzose kusashanda kabhoni. rinogona kuitwa hemodialysis, kumanikidzwa diuresis, uye pamberi chinyamunhari chinorwadza - mu / diazepam achiita uye nokukurumidza kuita barbiturates.