"Lasix" iri ampoules: mirayiridzo kushandiswa, chipimo chemushonga

Ndezvipi diuretics? It zvinodhaka vane zvakasiyana namakemikari zvivako, izvo tunodzivisa reabsorption munyu nemvura renal tubules, uyewo kuwedzera excretion hwavo weti. Uyezve, mishonga yakadaro kuwedzera weti kugadzirwa, kuderedza mvura tigutsikane iri serous in uye mune dzimwe nzvimbo dzomuviri.

Chinonyanya nzira yakakurumbira chinhu diuretic chinodhaka "Lasix" (ampoules). The chipimo chemushonga zvinodhaka, mirayiridzo yaro uye zvairatidza zvinokurukurwa pazasi.

Chimiro chinodhaka, ayo kavha, murwiyo

Izvo zvinoumba rine mishonga "Lasix" (mu ampoules)? Mirayiridzo yokushandisa inoti chikuru fuma rokugadzirira uyu furosemide. Uyewo zvinosanganisira yavaibvisa chloride, mvura jekiseni uye yavaibvisa hydroxide.

mushonga Izvi kutengeswa sezvo chingapedza W / o kana w / W chourongwa. Zviri pachena uye asina ruvara.

Yakabereka muiti ichi murima magirazi ampoules mhosva pfungwa, izvo ndokurongedza muchitokisi pepa rehurukuro kubva epurasitiki.

mashandiro chiito

Sei mushonga "Lasix" (mu ampoules)? Mirayiridzo dzokushandisa (intramuscularly mumiririri uyu anofanira kuzviita chete muzvipatara anokosha nyaya) rinoti zvakasimba kuita diuretic sulfonamide rinobva.

Active medicament anokwanisa ichivharira hurongwa chokufambisa kuti potassium ions, yavaibvisa uye kuiisa chlorine huru dhipatimendi loop pamusoro Henle. Ndokusaka chiito salureticheskim akati mushonga kunotsamira kusvika yaro renal tubules.

Diuretic ehupfumi kushuma zvinoreva chokuita kwacho kudzvinyirira yavaibvisa chloride reabsorption mu akati chidimbu (loop pamusoro Henle). Kana rwechipiri migumisiro, yevaifungidzirwa zvinosanganisira kuwedzera weti vhoriyamu uye potassium secretion mune distal tubule. Uyewo panguva imwecheteyo nayo kunowedzera excretion calcium magnesium ions.

Akadzokorora kwokubatsira mushonga hazvideredzi yayo diuretic basa. Izvi imhaka yokuti mushonga mu mubvunzo anokwanisa zvakamboda kukanganisa glomerular-tubular dzinovaka.

Hatigoni kutaura kuti "Lasix" mhinduro kunokonzera kurudziro (dose-kubatsirwa) ari renin-angiotensin-aldosterone hurongwa.

Features zvinodhaka

Zvii zviri yo "Lasix" chinodhaka (ampoules)? Mirayiridzo Kushandisa zvinotaurwa kuti mwoyo kukundikana ane mushonga kunoderedza mutoro uye kumanikidzwa vari arteries (pulmonary) uye zvinodiwa ventricle kuruboshwe. Uyezve, mushonga uyu ane hypotensive mugumisiro kuti zviri kukonzerwa kuderera cheBhuku ropa (achiparadzira), kuwedzera yavaibvisa excretion uye kuderera mune tsandanyama siyana (chechetere) ari vascular vasoconstrictor migumisiro.

Dose-muyanzvi natriuresis uye diuresis vakachengeta apo akatora mushonga ari dose pamusoro 10-100 MG. Pashure intravenous simba 20 MG diuretic mugumisiro aona pashure awa ¼ uye iri mberi kwemaminitsi 180.

Refu aizomupa kwokubatsira nevamiririri zvakanyanya kukunda inodzokororwa bolus. Zvinofanira kucherechedzwa kuti mishonga zvakawandisa dosages kuwedzera kushanda muna varwere haina kuchengetwa.

pharmacokinetic ehupfumi

Chii kinetic parameters kuri muna zvinodhaka "Lasix" (mu ampoules)? Mirayiridzo yokushandisa chinoratidza kuti bhuku kuparadzira vanoshingaira fuma gadziriro iri 0.1-0.2 litres por 1 kg nokushivirira uremu.

Furosemide zvakanaka asunga kuti mapuroteni uye yabudiswa kuchinja maererano secretion iri proximal tubule.

Terminal hafu-upenyu mushonga pashure intravenous aizomupa ingangoita uye maawa nehafu. The chikuru wemafuta zvinodhaka riri yabudiswa muna mukaka uye kupinda munharaunda yacho placental chipingamupinyi.

Zvairatidza kuti kushandiswa kugadzirisa

Ndezvipi zvirwere varayire majekiseni "Lasix"? Mirayiridzo dzokushandisa (ampoules / m uye / muna) rinoti kuti zvinodhaka zvichiratidza dzinotevera inoti:

• edematous chirwere mwoyo kukundikana chirwere hunhu;
• chirwere pamwe edema renal chisingaperi kukundikana mhando;
• edematous urwere pakati rikwanise mwoyo kutadza unhu;
• chenjera renal kukundikana, kusanganisira kutsva uye pamuviri (kuitira kutsigira Urume excretion);
• chirwere edematous nezvirwere zvakasiyana-siyana chiropa (somunhu nopindirana kurapwa pamwe aldosterone mhandu);
• chirwere edematous pamwe nephrotic chirwere (kurapwa chaicho chirwere);
• musoro uropi edema;
• Kudzosera diuresis rutsigiro munguva namakemikari chepfu (i.e., yeimwe vari yabudiswa ne itsvo dziri kuchinja chimiro);
• vane chirwere cheBP dambudziko.

Akasununguka nokuda pakatanga mumushonga

Mune zvimwe zviitiko, unogona kupinda mhinduro "Lasix" (mu ampoules)? Mirayiridzo kushandiswa (vana kushandisa chokushandisa ichi nekambani yoga) rinotaura kuti mushonga irege kushandiswa:

• zvakakomba hypokalemia;
• renal kukundikana (kusanganisira anuria);
• zvakakomba hyponatremia;
• hepatic precoma uye chaanoziva;
• hypovolemia (ropa shoma kumanikidzwa kana pasina) kana kupera mvura mumuviri;
• pamuviri;
• unopinza akaratidza kutyorwa kuri water drainage kuti weti kubva chero kupi (kusanganisira yaitsigira divi maronda ari Urinary turakiti);
• achiyamwa;
• Hypersensitivity kune huru pakugadzira;
• kana uri sema kune sulfonamides.

Kushandisa zvinodhaka nokungwarira

Mune zvimwe zviitiko nokungwarira hwakanyanya inofanira kushandiswa zvinodhaka "Lasix" (capsules)? Mirayiridzo dzokushandisa inoti kuti vatarisire kuti zvinodhaka kwakadaro kunofanira kuva pa:

• inoti iyo kunyanyisa richikwidibira ropa nevamwe ngozi (semuenzaniso, stenotic maronda ari coronary kana chepfungwa arteries);
• hypotension;
• gout;
• kana pachena Isimba rakadini rinogona kubudiswa cheshuga;
• chenjera myocardial infarction (kusanganisira mikana yakawanda cardiogenic kuvhunduka)
• hepatorenal urwere;
• chinonzi systemic lupus erythematosus;
• havachanyatsogoni Urinary water drainage (kweprostate gland hyperplasia isiri yekenza, hydronephrosis, aienda pamusoro urethra);
• hypoproteinemia;
• kunzwa kurasikirwa;
• manyoka uye pfungwa nomuviri zvemwana asati;
• ventricular fibrillation;
• mune rokusamhanyira vacheche.

Drug "Lasix" iri ampoules: mirayiridzo kushandiswa

A Hupenyu nokuti mushonga maererano vakasarudzwa zvaiitwa vanofanira mishonga chete ane ruzivo nyanzvi. In agadza chinodhaka yakadereresa chipimo chemushonga inofanira kushandiswa, izvo zvakakwana kuita zvinozoita.

The medicament chinotarisirwa intramuscularly chete asina mhosva. Kazhinji, zvinonzi akadurura nomutsinga (zvishoma nezvishoma 4mg paminiti).

How zvikuru inofanira kushandiswa "Lasix" iri ampoules kugadzirisa? Chipimo chemushonga kuti muiti ichi kunobva humbowo.

• Edematous chirwere mwoyo kukundikana chirwere hunhu.

The kwokutanga dose kuti ichi kunofanira 20-80 MG pazuva. Kazhinji, rinenge anosarudzwa maererano diuretic mhinduro. With chirwere ichi chipimo chemushonga zuva zvinodhaka rakakamurwa katatu.

• Edematous chirwere mumwoyo kukundikana chenjera.

The kwokutanga dose kuti ichi ndicho 20-40 MG. Kana waida, rinogona kugadziriswa.

• Edematous chirwere pamwe chirwere renal kukundikana.

Vanaamai vakadaro zvinoda kungwarira dose vakasarudzwa. Kunowedzera zvishoma nezvishoma, zvokuti Urume kurasikirwa kunoitika zvishoma nezvishoma.

• Chenjera renal kukundikana mhando (kutsigira Urume excretion).

Asati atanga kurapa anofanira kubviswa hypotension uye hypovolemia, uyewo kutyora asidhi-nechigadziko uye electrolyte mamiriro. Initial intravenous chipimo chemushonga panguva chirwere kwakadaro 40 MG.

• Puffiness of nephrotic syndrome.

In mamiriro ichi, kutanga dose zvinodhaka reserves 20-40 MG pazuva. Kazhinji, anosarudzwa pachishandiswa diuretic mhinduro.

• Syndrome zvimba zvirwere chiropa.

Panyaya iyi, kuti mushonga anopiwa sechipo mhando adjunct kurapwa kuti aldosterone mhandu.

• uropi edema, vane chirwere cheBP dambudziko.

Sapamazuva zvirwere zvakadai mhinduro rinofanira kupiwa "Lasix" (ampoules)? Mirayiridzo yokushandisa inoti kutanga dose ose akati medicament kana zvinhu zvinofanira kuva 20-40 MG (via intravenous bolus). Zvichienderana kubata dose zvinogona kugadziridzwa.

• Kutsigirwa kumanikidzwa diuresis kwemakemikari chepfu.

medicament ichi chinotarisirwa pashure intravenous aizomupa electrolyte mhinduro. The kwokutanga dose hazvisi 20-40 MG. Panguva kurapwa zvakafanira kudzora uye kudzorera vakarasika zvinwiwa.

chiito divi

Ko akaipa migumisiro agadzirise "Lasix" (mu ampoules)? Mirayiridzo yokushandisa maererano zvinotevera marwadzo:

• chloropenia, hyponatremia, metabolic alkalosis, hypomagnesemia, hypokalemia, hypercalcemia;
• kupera muviri, hypovolemia;
• kunoderedza BP, kunzwa zviri kumanikidza mumusoro, dzungu, ziso nenyonganiso, nomusoro, tachycardia, hope, pakaparara, utera, muromo yakaoma;
• vakawedzera kwevari triglycerides uye remafuta akawandisa, uye ropa kwevari urea uye creatinine;
• havachanyatsogoni shuga kubvumidza, interstitial nephritis;
• kuda kurutsa, paresthesias, kurutsa, manyoka, intrahepatic cholestasis, rikwanise pfungwa nomuviri zvemwana asati, nephrocalcinosis mu preterm vacheche;
• kunzwa kurasikirwa, mapundu, tinnitus, pruritus, exfoliative dermatitis, rashes kana bullous maronda ganda, erythema multiforme, fivha, purpura, photosensitivity, vasculitis;
• thrombocytopenia, leukopenia, eosinophilia;
• agranulocytosis, deposition calcium mu itsvo, aplastic kupererwa neropa;
• nounyoro panguva jekiseni nzvimbo.

Kana kuona chiremba?

Zvino munoziva, kuti divi kuita mhando aigona kuti mhinduro "Lasix" (ampoules). Mirayiridzo zvokushandisa (mu vana nevakuru, mushonga kunoita chete nemigumisiro) anoti kuchinja mumufananidzo ropa, uyewo kwazvo ganda sema kana anaphylactic siyana anogona kukanganisa upenyu varwere. Naizvozvo, kana chero kuratidzwa kunaka vanofanira kuona chiremba pakarepo.

matanho okudzivirira

Zvaunofanira kuziva usati kushandisa mushonga "Lasix" (mu ampoules)? Mirayiridzo kushandiswa (nokuti katsi inzira uye kwete akakodzera dzinovaraidza asina basa) inopa kuti pakutanga yokurapa asati zvakafanira haabatanidzi kuvapo wakatarwa kuvhiringidzika water drainage kuti weti.

Panguva kurapwa zvinokurudzirwa kudya zvokudya kuti potassium yakawanda. Zvikasadaro, unofanira kutora potassium-kukudzivirirai nevamiririri.

Vamwe nemishonga kunogona kukanganisa munhu anokwanisa pfungwa, izvo ngozi chaizvo kana kushanda zvakaoma michina uye kutyaira.