Karusiyamu citrate: hunhu, mashandiro basa, kushandiswa

Unorema Ca ari mumuviri akura (anenge 99%) ine mapfupa rinenge zvinosanganisira hydroxyapatite crystals. In serum mhuka dzakawanda, karusiyamu wevasungwa anenge 3 mmol / L (10-12 MG / 100 ml) uye ndiye kugara. Daily nokufamba pakati constants haapfuuri 3-5%. Ca kunokosha kuti dzose kushanda tsinga. The neuromuscular synapses karusiyamu ions pave kusunungurwa acetylcholine uye choline remubatanidzwa rayo Kanotokonya, uye kana kusashanda ne acetylcholine zvakawandisa cholinesterase - imwe enzayemu kuti hydrolyzes acetylcholine.

Ca ions huri sarcoplasmic reticulum, kusimudzira kudyidzana pakati actin uye myosin, i.e. rutapudzo kuti tsandanyama fibers. Izvi rinoitwa pamberi magnesium ions.

Karusiyamu ions Activate ari enzymatic pezvakaitwa ari kwokutanga nzendo kweropa - pakugadzirwa thrombin uye thromboplastin. Nokusungwa calcium ions mu plasma oxalate kana citrate kunodzivisa kweropa.

Recently akaratidza rakasiyana nemamwe muchinangwa calcium muchitokisi basa, apo cytoplasm, ayo wevasungwa hakuiti kupfuudza 10-6 nhuta. Panguva cellular pamwero, pane zvitanhatu dzinokosha vasiri pezvakaitwa kuti kuvimba wevasungwa calcium ions:

a) gwenya basa masero (tsandanyama marwadzo);

b) excitability masero izvo vanokwanisa kuti vaunze electrostatic chiito zvinogona (tsandanyama matauriro, tsinga zvairatidza photoreception cardiac marwadzo);

c) kufefemuka zvinhu kuti synthesized muchitokisi (secretion pamusoro hormone neurotransmitters);

g) ari kwebasa rinofanira soluble zvinhu muchitokisi kubudikidza vesiculation (phagocytosis);

d) chinhu intracellular muviri (kwetunhu shuga, lipolysis, etc.);

e) Sero kubereka (mitosis uye oocytes fertilization, dzisingaoneki motility).

Ca ions pamwe chete dzakananga mapuroteni zvinopa elasticity neukukutu mafupa. mushonga ano anoshandisa kwokugadzirira ane ions calcium (glyukanat, citrate, chloride, lactate, carbonate, phosphate, etc.). Karusiyamu citrate ndicho chatinonyanya kukosha. The chikuru Danho calcium yokusunungurwa kubva ayo zvivako (phosphates, sulfates, chlorides) pamwe Organic uye chicherwa zvinoumba zvokudya rinowanikwa mudumbu nokupesvedzera iine acid chloride uye proteolytic makemikari. Carbonic asidhi uye phosphoric iine acid karusiyamu munyu acidic unosvikirwa mudumbu vari dissociated, uye calcium yakawanda iri ionized chimiro kana zvakaoma pamwe soluble chelates anopinda diki ura. Saka, mune kwakaderedza secretory kushanda mudumbu Kuwanikwa Ca kubvisa haina kukwana, zvinogona mumwe zvikonzero dhefisiti kuti chinhu ichi pamuviri. Karusiyamu citrate yakanakisisa zvazvichanyungudutswa ari acidic ezvinhu mudumbu. Ionized karusiyamu nyore chinopinda zvoutachiona membranes, kunyange napakati placenta nokuidzivirira. Chikuru (anenge 80%) calcium yabudiswa muna mutsvina yadzo, weti goho vanenge 20%. Nekuti karusiyamu citrate nani citrate munyu inosimudzira rutapudzo kuti oxalate iri weti, kushandisa zvinodhaka haana kuita kuti paumbwe itsvo namabwe.

Unowanikwa kuti usiku kusashanda kusarudzwa chicherwa munyu kubva mumuviri. Nokuti vanachiremba dzinorumbidza kutora karusiyamu citrate masikati kana manheru. Akaratidza kunaka correlative ukama pakati dose calcium kugadzirira uye mishonga basa. Zvinorevei? karusiyamu citrate iri nani yokuita zvinoitwa muviri mishonga diki. Naizvozvo zvakanaka kutora mushonga kakawanda pazuva. Nokuti mumwe zera boka akasimbisa vasiri karusiyamu rinodyiwa dzemunharaunda. Karusiyamu ushandiswe somunhu preventative uye dzokurapwa (kusimba, osteoporosis, osteomalacia, nokuti kunosimbisa mazino enamel) chinangwa. Potassium citrate iri nachiremba mwoyo kukundikana, BP, normalization pamusoro asidhi-nechigadziko uye mvura-munyu zvakanakanaka mumuviri.