"5-NOC" - wongororo kugadzirira

Pasinei chokwadi kuti muviri womunhu akapiwa kutapata uye anokwanisa kurarama nezvirwere zvakawanda ndoga, pane utachiona uye zvirwere zvinogona kukundwa chete tichibatsirwa kurapwa. zvinodhaka kwakadaro kunogona tunodzivisa kana kumisa kuwedzera pathogenic zvipenyu, nokudaro kubvisa nyaya chokutsva. Mahwendefa vari "5-NOC" The boka mishonga yakadaro. Testimonials kuratidza kwavo efficacy mukuru pakurapa zvirwere genitourinary hurongwa. Uyezve, chokushandisa ichi akakwana kuti kudzivirira dzokororo ine kuzvimba mune chirwere siyana zvirwere.

Active fuma

Nitroxoline vanoshingaira fuma une zvinodhaka "NOC-5." Iri chakaita zvokugadzirwa inotungamirwa, rinobva 8-hydroxyquinoline. Kuburikidza chikamu ichi, mushonga kupinda muviri unotanga kutsvaka masero zvigare uye tunodzivisa DNA yavo. mashandiro vanosarudza kuita inobvumira kumisa kuwandisa pathogenic utachiona uye kwete kukuvadza masero utano.

Kunze nitroksolin anopinda maitiro pamwe yezviri nucleic acids uye makemikari ane simbi mumakeji dzavo. The fuma anopa pakupora muitiro pathogenic utachiona ane simba bactericidal Varwisei navanopinda chakarondedzera tusingaoneki. Saka zvinobudirira paacharwisa utachiona nemishonga mamwe mapoka inorwisa mabhakitiriya. Medicine "NOC-5 'ratings kunosimbiswa kuti inobudirira uye chipa nzira pazvirwere zvinokonzerwa notumwe, mabhakitiriya, uye zvirwere utachiona yakakwirira nemishonga nezvimwe zvinodhaka zviri antibacterial uye akambozvishandisa kuuraya utachiona chiito.

Release chimiro uye sezvamunoita

The medicament iri asunungurwa muchimiro zvemapuranga mahwendefa. Vane orenji kana yeyero, muchimiro yakapoteredza, lenticular, pane maitiro kubwinya. Huru achishingaira chirungiso - nitroksolin. Ebetsero zvinoumba murwiyo: sucrose, colorant E110, carboxymethylcellulose, lactose.

Chii tusingaoneki vachirwa zvinodhaka

Cherechedza kuti idzidziso ane achitaura kushanda uye rakanyatsojeka inobudirira kumirisana nevamwe okuva utachiona:

• Kurovedza uye anaerobic giremu-akanaka zvinenge - Enterococcus faecalis, Streptococcus spp. (Pneumoniae utachiona, pyogenes).
• Anonzi Staphylococcus spp., Utachiona aureus, Bacillus subtilis, Corynebacterium spp.
• Anaerobic uye Kurovedza tusingaoneki (giremu) - Klebsiella spp, Proteus spp, Shigella spp, Salmonella spp, Haemophilus influenzae, Enterobacter spp, Escherichia coli coli, Neisseria gonorrhoeae ......
• Zvirwere zvinokonzerwa pamusoro Mycobacterium tibhii, pamusoro Mycoplasma hominis, Trichomonas vaginalis, kuti Ureaplasma urealyticum.

MAUMBIRWO, dermatophytes, notumwe pamusoro Candida, zvimwe zvinenge zvichikonzera fungal zvirwere yakadzika - zvirwere ava uyewo vanobudirira mukuderedza zvinodhaka "5-NOC". Reviews vanachiremba vanoratidza nekugona zvinodhaka kuti kuderedza adhesion pakati uropathogenic zvipenyu pamadziro anobudisa mushonga zvishoma nezvishoma (kubudisa weti kubva varwere) uye Urinary turakiti epithelial rukoko.

kana dzakabatwa

Nokuda kuti pane zvakawanda zvinodhaka chikumbira kutsungirira zvinotevera zvirwere:

• Chirwere, chenjera, idzokororo chirwere (kutapuriranwa etiology) Urinary turakiti kunokonzerwa utachiona giremu negative uye giremu-akanaka uye hunokuvadza.
• Epididymitis.
• Pyelonephritis: chisingaperi uye rikwanise chimiro.
• Urethritis.
• Cystitis.
• Adenoma uye carcinoma (akanaka) kweprostate.
• Kudzivirira zvirwere (idzokororo) Urinary turakiti.
• Shandisa pashure chirwere uye maoparesheni ari Urinary turakiti: itsvo pokuvhiyiwa, cystoscopy, catheterization.

It rakaisirwa zviripo taurira zvakakwana kurapwa zvichienderana kwokuomerwa chirwere kunogona chete kuva chiremba. Mahwendefa "5-NOC" Nyanzvi akaongororazve izvozvo kunosimbiswa kuti mukuru bioavailability - vanenge 90%. Ivo vari kukurumidza kunakidzwa nemudumbu uye kusvika soro yeplasma wevasungwa mumaawa 1.5-2.

Pharmacokinetics

The gadziriro ane yakaderera kugona chokubatanidza pamwe mapuroteni eplasma. The soro Kuwanda vanoshingaira fuma zvinoratidzwa weti murwere. The mushonga rinoita kunyanya chitaka uye yabudiswa pedyo neitsvo. Mumwe chitsama zvinodhaka rinobviswa muviri ari bile - nguva 2 maawa zvinofanira kucherechedzwa kuti mashoko pamusoro pharmacokinetics zvinodhaka muvana, vanhu vari kukwegura uye varwere renal insufficiency uye chiropa vasina kudzidza .. Naizvozvo, unofanira kuwana anokwanisa chiremba kubvunza asati varwere mapiritsi "5-NOC". Reviews Nyanzvi dzinoti vana kwazvo akashivirira mishonga kana hwenguva zvaidiwa chipimo chemushonga uye kurapwa regimens. Kunyanya kutarisirwa vanofanira kutungamirira mwana pakuongorora, izvo haana asvika 3 makore.

How kutora

Zvinokurudzirwa kuti kutora mushonga munguva kudya kana pashure pacho. Mahwendefa regai kutsenga, medza rose, kushambidzwa pasi nemvura yakachena. Zvakakwana mishonga:

• Varwere Adult - 100 kusvika 200 MG, kusvikira 4 kanomwe pazuva. Cherechedza kuti pasi ezvinhu kuramba kushandiswa mahwendefa mwero inogona haapfuuri mazuva 30. Zvisinei, zvingangove mapoka yokurapa pamwe alternation: mazuva 14 kunwa mapiritsi, mazuva 14 havana kutora zvinodhaka. Nzira Izvi zvinoita kuti vawane mishonga kwemwedzi inoverengeka.
• Kudzivirira zvirwere pashure maoparesheni, chirwere matanho - 100 MG kusvika 4 kanomwe pazuva. Kwakadaro medicament kugamuchirwa muoti rinovapo kusvika 3 mavhiki. Nokuti varwere havachanyatsogoni chiropa nerevane itsvo kwokutanga dose ndiyo 50% of kunokurudzirwa.

Zvinofanira kucherechedzwa kuti zvinodhaka riri "5-NOC" cystitis, murefu uchapupu zvinoratidza ichi, nokukurumidza kunoderedza kuzvimba uye anobvisa marwadzo. Zvisinei, kunyange chiitiko kunobatsirawo yokurapa haina yakarumbidza zvakamboda kukanganisa kosi waakaudzwa nachiremba, zvimwe pane mukana dzokororo.

The chipimo chemushonga vana

Yeuka kuti imwe zvakakwana chipimo chemushonga mwana anogona kudoma chete chiremba pahwaro yacho ongororo. mushonga kakawanda ushandiswe sezvinotevera:

• Babe kubva 2 kusvika 12 mwedzi kukarukureta yakaitwa, inobva mwana wacho muviri uremu: 25 MG / makirogiramu pazuva. mishonga All anofanira akakamurwa 4 mishonga panguva nenguva. Duration yokurapa inobva mazuva 10 kusvika 3 mavhiki. Kana chakakomba chirwere - kusvika 1 mwedzi.
• Pazera 12 mwedzi 14 makore ushandiswe yaunodya 50 kusvika 100 MG kusvika 4 kanomwe pazuva. The kosi vagara vandifungira nyanzvi, asi chaiparira kugamuchira haikwanise kupfuudza mazuva 30. Kana interleaved muoti 2 weeks - womuchato, uye 2 weeks - kuregawo kutenderwa kwenguva kushandiswa zvinodhaka "5-NOC". Vana, vanachiremba wongororo pamusoro ichi anoratidza zvinoreva zvinofanira ushandiswe chete muzviitiko kana kurapwa nedzimwe mishonga zvakaratidza isashande.

Possible nemishonga

Cherechedza kuti divi migumisiro Varwere vari zvisingawanzoitiki, asi zvinokosha zvinoitirwawo panowanikwa yavo pakarepo kutaura chiremba. Kuti kubvisa zvinodhaka uye kuitisa symptomatic kurapwa pashure kurapwa "5-NOC". Instruction anodzokorora vanachiremba vanoti zvinotevera zvinoratidza akaipa pakurapa:

• Kurutsa, kupera chiropa basa, kuda kurutsa, kudya mu zvisingawanzoitiki zviitiko.
• Tachycardia.
• Paresthesia, polyneuropathy.
• Havachanyatsogoni kufambisa, dzungu, nomusoro, dzimwe nguva kurasikirwa chavanoziva.
• Optic neuritis (pamwe kwenguva refu kushandiswa mahwendefa).
• Urticaria, mapundu, peeling ganda.
• Thrombocytopenia, dzimwe nguva weti staining zvakadzama tsvuku Hue, kuwedzera uric iine acid indekisi muropa plasma.

Kazhinji, yaivhuvhuta zviitiko zvose zvakaitika nokukurumidza pashure zvizere discontinuation zvinodhaka, "5-NOC". Testimonials kukuratidza kunzwa kurwara, asi kana ovhadhozi kana murombo abvume.

Contraindications

Kana murwere ane sema maitiro kana aikanganiswa mumwe zvinoumba murwiyo, zvinonzi mbidzwa kupa mushonga. Hazvina yakarumbidza kushandisa medicament panguva achiyamwa, tsanga, zvemamiriro chiropa nerevane itsvo.

Zvinokosha kucherechedza kuti zvinodhaka riri "5-NOC" vakadzi inofambiswa pamusoro ichi anoratidza rinowanzoshandiswa ushandiswe panguva yepamuviri. Hazvina kumisa nyaya kukuvadza utano zvose mai ramangwana uye azvarwa. Kazhinji, mushonga wacho nachiremba rikwanise cystitis, kusangana nekutsi kwemukadzi noutachiona uye fungal kuratidzwa (thrush).

Hazvina zvakafanira kutora mushonga panguva iyoyo pamwe mishonga kuti ane hydroxyquinoline. hunokachidza chepfu zvinogona kuitika kubva pachisara kuti basa fuma pamuviri.