"Simvastatin": nhoroondo, zvairatidza kuti kushandiswa, mutengo uye analogues

Sei Ndinoda mishonga "Simvastatin" sei? Testimonials pamusoro mushonga zvichakurukurwa zvishoma mberi. Nesuwo kukuudzai pamusoro zvinodhaka izvi inowanika muchimiro zvaakanga ane zvairatidza, nemishonga uye contraindications dzomuzana, sei tinorasikirwa, sei inofanira kunyatsobudiswa kuiswa uye zvichingodaro. D.

Kavha, Product chimiro uye sezvamunoita

Drug "Simvastatin" anoenderera mberi Sale muchimiro mahwendefa. Vane kumativi biconvex chimiro pamwe chiratidzo paruoko rumwe, uyewo chena. Coated pamahwendefa, mahwendefa akadaro ane 10 MG ose simvastatin. Uyewo medicament zvinosanganisira ebetsero zvinoriumba sezvo butylhydroxyanisole, lactose, magnesium stearate, starch prozhelatinizirovannogo, talc, uye microcrystalline cellulose.

In pasuru, unogona kutenga mushonga "Simvastatin"? Zvairatidza kuti kushandisa mari raanotaura mirayiridzo, iyo iri imwe remidzanga makadhibhokisi. Ikokowo vanoiswa uye Maronda akasiyana maviri pamwe mahwendefa (10 zvidimbu).

Pharmacological migumisiro

Sei mushonga "Simvastatin"? Nyanzvi Guest dzinoratidza kuti zvinodhaka izvi lipid-richikwidibira. Anogadzirwa zvokugadzirwa nevanhu.

Vaiona mumiririri chinhu akaneta lactone. Muvanhu, zviri hydrolyzed, uye zvadaro anoumba munhu hydroxy-asidhi rinobva.

Kushandisa zvinodhaka haakonzeri kuunganidza muchetura. Zvinonzi nokukurumidza rinoita uye rinobatanidzwa pezvakaitwa akawanda synthesizing.

The ehupfumi zvinodhaka

Zvakaita nzvimbo yacho mishonga "Simvastatin"? Reviews vanoti chokushandisa ichi chinobatsira kuderedza yeplasma kwevari triglycerides, zvachose remafuta akawandisa uye yakaderera arambe achirema lipoprotein.

The kuchirapa mugumisiro iwe pashure vanotanga nokutora mushonga kunoitika muvhiki mbiri. Zvakaitwa zvinodhaka inoramba akatsiga kwenguva ya kurapwa. Pashure kudzimwa mahwendefa remafuta akawandisa pamwero zvishoma nezvishoma anodzoka kutanga kuita.

Pharmacokinetics

zvinodhaka "Simvastatin" rini kunyura? Nyanzvi Guest vanoti Absorção de Água mari chaizvo. Pamusoro kugamuchira mushonga kupinda soro wevasungwa kwayo muropa zvasvika pashure maawa 1.5-3 uye ipfupi 90% pashure maawa anenge 12. Kutaura plasma iri vanenge 95%.

The muviri zvinodhaka ari chiropa. Hafu-upenyu metabolites ndiyo maawa anenge maviri.

Akaratidza medicament pamwe mutsvina yadzo uyewo kuburikidza neitsvo.

Drug "Simvastatin": zvairatidza yokushandisa

Of Mari rakarumbidza zvokushandisa hypercholesterolemia, uye nechirwere chemwoyo. Taurira mushonga kwakadaro kunofanira chete kuva chiremba mushure kuongorora zvokurapa.

Saka chero zvazvingava unogona kutora mapiritsi "Simvastatin"? Kubva zvazvinoreva iri ratakapiwa? Maererano mirayiridzo, mushonga inokurudzirwa kana:

• chikuru hypercholesterolemia;
• ari ineffectiveness zvataidya pamwe yakaderera remafuta akawandisa kudya uye nevamwe vasiri zvinodhaka kupindira (uremu, kurovedza muviri) Varwere vane coronary atherosclerosis;
• aibatanidza hypertriglyceridemia uye hypercholesterolemia, usina kugadziriswa panyama zvinorema uye chinokosha kudya.

Zvii zvimwe zviitiko ushandiswe mishonga "Simvastatin"? Zvairatidza kuti kushandisa nzira iyi funga izvozvi:

• kudzivirira myocardial infarction;
• kuderedza ngozi kusagadzikana mwoyo (semuenzaniso, zvinopfuura ischemic kurwisa kana nesitiroko);
• retardation kuti atherosclerosis mune coronary midziyo.

Contraindications

Zvino kuti unoziva chii kunwa mushonga "Simvastatin". Zvairatidza kuti kushandiswa chishandiso kunge kukurukurwa pamusoro. Zvisinei, mushonga uyu pane contraindications. Zvinotevera ezvinhu zvinoshanda kwavari:

• tsandanyama chirwere (kana inonzi myopathy);
• chiropa chirwere kuitika yezviri chokutambudzika;
• makore 18;
• Kuramba pakukwirira chiropa makemikari (kusanganisira asingazivikanwi etiology);
• hypersensitivity kuti mushonga kana kuti ayo mumwe zvinoriumba (kusanganisira lactose kusashivirirana);
• hypersensitivity kune dzimwe nzira statin dzakatevedzana.

Kunyatsogadzirira mutambo

Medicament "Simvastatin", mitengo iri pasi apa, Kunyanya hanya rakapiwa varwere vanoshungurudza doro, uyewo vanhu kutevera nhengo transplantation (pamwe immunosuppressive kurapa).

Uyezve, nyaya zvinoreva nokungwarira abatwa ezvinhu kutungamirira kukudziri- renal kukundikana (semuenzaniso, hypotension, chenjera zvirwere zvinotapuriranwa hunhu, akaderedza, kana, nekusiyana, yakawedzerwa tonus kuti tsandanyama rinenge akaratidza metabolic uye kwemakemikari anobudiswa zvinetso, pfari, electrolyte nepakati nenyonganiso, kuvhiya, kusanganisira mazino kunotevera).

Drug "Simvastatin": kushandiswa uye chipimo chemushonga

Vaiona asati kutangisa kurapa zvinoreva murwere aifanira mureza hypolipidemic kudya. Sezvineiwo, zvinofanira kutevedzerwa yose yawapiwa.

"Simvastatin" piritsi raitongwa kamwe zuva manheru. Nepo kutora mushonga uyu haafaniri uwirirane kudyiwa zvokudya.

The yakarumbidza chipimo chemushonga kuti zvinodhaka Mabatirwo hypercholesterolemia ndiyo 10-80 MG pazuva.

dose kuchinja yaifanira panguva pamwedzi zvikamu. Chokutanga, murwere vanofanira 10 MG, ipapo 20, 30 uye zvichingodaro. D. Kazhinji kacho ari Zvakanyanya Kunaka Panguva Yepamuviri kuchirapa mugumisiro inotengwa kana kugamuchira 20 MG zvinodhaka.

The chipimo chemushonga zvinodhaka anoenderana murwere zera, ayo ezvinhu uye zvichingodaro. Panyaya iyi, akadaro mushonga unofanira kugadza chiremba, pashure kuongorora murwere uye zvokurapa kuongorora.

nenjodzi

Kungofanana zvinodhaka, medicament "simvastatin" anewo nemishonga. Pakati Zvinonyanyozivikanwa zvinotevera:

• Abdominal marwadzo, hepatitis, kupatira, pfungwa nomuviri zvemwana asati, flatulence, kurutsa, ichirova chiropa makemikari, manyoka, uye svoto.
• Asthenic urwere, havachanyatsogoni pfungwa kuravidza, nomusoro, madzerere, anzwe dzungu, peripheral neuropathy, kushaya hope, paresthesia, tsandanyama chinyamunhari chinorwadza.
• Angioedema, eosinophilia, polymyalgia rheumatica, urticaria, lupus-kufanana urwere, vasculitis, dyspnea, thrombocytopenia, kupiswa, vakawedzera erythrocyte sedimentation zvazvingava, Flushing ganda, fivha, photosensitivity, chearthritis.
• Skin mapundu, alopecia, dermatomyositis, kuvaviwa.
• Myopathy, rhabdomyolysis, myalgia, utera, tsandanyama chinyamunhari chinorwadza.
• Kupererwa, akaderedza potency, mwoyo, renal kukundikana (chenjera).

Mirayiridzo Special pakugamuchira medicament

Asati kushandisa chigadzirwa unofanira kuverenga rairo nokungwarira. Rinotaura kuti:

• pamberi kutanga kurapwa zvakakodzera kuti azodzidza chiropa;
• zvinodhaka "Simvastatin" harifaniri kubatwa kana renal kukundikana uye mikana yakawanda rhabdomyolysis;
• mishonga inogona nemigumisiro azvarwa;
• haina yakarumbidza kutora mapiritsi vakadzi zera rokubereka vasingazivi kubata pamuviri;
• panguva kurapwa hakufaniri kunwa doro;
• panguva mushonga, murwere unofanira kuita zvinoenderana hypolipidemic kudya;
• mawa negashiro bhuratifuru muto anogona kuwedzera ukuru kwokuomerwa divi siyana;
• gadziriro kungashanda somunhu monotherapy, uye pamwe chete nokushandisa bile asidhi sequestrants.

Analogs uye Mari zvinodhaka

Zvino munoziva kuti ndiyo mushonga "Simvastatin". Analogues, mutengo mushonga uyu achapiwa zvino.

Kana hazvibviri kushanda ichi nzira inogona kutsiviwa nevamwe zvinodhaka akadai "Simvakard", "Avestatin", "Holvasim", "Aktalipid", "Sinkard", "Aterostat", "Simplakor", "Vasilip", "Simli" "Vero -Simvastatin "," Simgal "," Zovatin "," Simvor "," Zocor "," Simvastol "," Zorstat "," Simvalimit "," Ovenkor "," Simvakol "," Simvageksal "uye t. d.

Price zvinodhaka "Simvastatin" haasi mukuru chaizvo uye anenge 240 rubles kuti mahwendefa 20.

Reviews kuti medicament

Varwere vakawanda ndamboita "Simvastatin" Mahwendefa, cherechedza yakakwirira kunyatsoshanda kwayo. The mushonga iri nokukurumidza lowers remafuta akawandisa, kudzivisa pave nezvirwere zvakasiyana-siyana.

Zvisinei, vamwe varwere vasingafari vaipfuura pashure kurapwa remafuta akawandisa pamwero rinobuda zvakare uye kazhinji anouya Muongororo yekutanga.