Kubva chii kunobatsira, "famotidine"? Mirayiridzo yokushandisa, zvechokwadi

Maiziva here kuti pane chii anobatsira "famotidine"? Pindura mubvunzo uyu unogona chiremba chete. Kana nguva yokuti zano chiremba musingadi, zvino tichataura pamusoro zvinodhaka ino munyaya ino.

Uchadzidza chii ehupfumi ati medicament, sezvo amire, panguva ipi zvirwere rinoshandiswa, chii chinobatanidzwa kwaro sezvamunoita, uye zvichingodaro.

Zvinoumba zvinodhaka kavha, uye chimiro tsananguro

In ipi kusunungurwa medicament "famotidine"? Manual rinoti chokushandisa ichi chinogona kuwanikwa dziri mahwendefa. Vane lenticular dzeraundi chimiro, uyewo firimu zvemapuranga zvisvundu dzi kana tsvuku.

Ndezvipi zvokubikisa kunosanganisira mushonga "famotidine"? The Kuronga zvinodhaka riri nyore: huru chirungiso - famotidine. Kunze nechepasi zvokunyama, chishandiso dzine mutsigiri, akadai microcrystalline cellulose, chibage starch, magnesium stearate, talc, nesilicon yakasviba uye croscarmellose yavaibvisa.

Panyaya mapiritsi, chinosanganisira macrogol 6000, hypromellose, talc, titanium yakasviba uye simbi oxide dhayi shava.

The Kutengeswa nehanya mushonga anouya mhoni packs it, izvo mumapepa pepa kavha.

Zvinofanira kusimbiswa kuti kugadzirira "kuti famotidine" izvo mirayiridzo pasi apa, anogadzirwa mishonga yakasiyana - 40 uye 20 MG.

Features zvinodhaka

Tisati tapindura mubvunzo chii chinoita "famotidine" vanofanira kutiudza kuti mushonga unoshanda. Maererano mirayiridzo, nyaya mumiririri iri blocker kuti H2-histamine receptors. Zvinoratidza Anti-urikanwi ehupfumi.

The chikuru zvacho zvinodhaka hunoita kuti kudzvinyirira pakati basal iine acid chigadzirwa (hydrochloric acid) mudumbu. Uyezve, famotidine kunoderedza kweiyi histamine, acetylcholine uye gastrin uye gastric muto kunowedzera ph, pepsin basa uye anoderedza kugadzirwa HCL.

Nemhaka iyi yakawedzera padanho glycoprotein inotungamirwa zvinoreva kuwedzera gastric madzihwa uye kweiyi prostaglandin usage. Kuburikidza secretion rehydrogen kubudirira uye musvine ronda kuporesa ehupfumi zvinodhaka.

mishonga Viewed kunobatsira kumisa ropa kubva mudumbu, achiporesa kukuvadzwa pamusoro wayo mucous uye scarring kunetseka maronda.

The ehupfumi zvinodhaka

Kugadzirira "Famotidine" (analogs mutengo zvinodhaka dziri pazasi) ane zvishoma chaizvo okuti hurongwa (oxidase) enzayemu cytochrome P450 ari chiropa.

Rawo mushonga uyu kunotanga pashure maminitsi 65, zvinotora inenge zuva.

The kinetics zvinodhaka

The medicament "Famotidine", vane kuverengwa dzinoturwa pazasi, pashure nemumuromo Kutarisirwa wefodya kubva ura. wevasungwa Its (kunonyanyisa) ropa kubudirira mukati maawa matatu.

Communication zvinodhaka mapuroteni eplasma ndiyo 15-20%. Zvinonzi yabudiswa muna mukaka waamai uye chinopinda kuburikidza placental chipingamupinyi.

Inenge 30-35% yezviri zvinodhaka fuma pasi kukurukurwa rinoita mune chiropa. Izvi unoumba S-oxide.

Kubviswa pakati chishandiso kunoitika kunyanya kuburikidza neitsvo. Inenge 27-40% zvinodhaka riri yabudiswa muna weti iri kuchinja chimiro. hafu-upenyu "kuti famotidine" nguva ndiyo maawa 3-4. Vanhu vane CC Rine mamiririta asingasviki 30 paminiti indekisi iri yawedzera kusvika maawa 11-12.

Kubva chii anobatsira "famotidine"?

Mune zvimwe zviitiko, kushuma mushonga waakaudzwa nachiremba? Maererano mirayiridzo, kugamuchira zvairatidza zvinodhaka ichi vari inotevera inoti:

• mastocytosis hurongwa;
• kuitazve dziviriro, zvomudumbu turakiti urikanwi chirwere;
• reflux esophagitis;
• erosive gastro;
• kudzivirira kuitazve, izvo chokuita nokushandiswa kwenguva yakareba NSAIDs;
• Zollinger-Ellison urwere;
• dzichipfekeka dyspepsia, iyo chokuita zvakawedzera basa (secretory) mudumbu;
• gastrointestinal maronda, mupfungwa uye symptomatic;
• Kudzivirira chido ose gastric muto varwere achirapwa kuvhiya pasi vakawanda yokutindivadza (i.e. Mendelson kuti urwere);
• vakawanda kwemakemikari anobudiswa adenomatosis;
• kudzivirira dzokororo kuti ropa, kusanganisira post-kushanda kumwedzi;
• Kudzivirira chido pneumonitis;
• neuralgia mukurwadziwa ari retrosternal kana epigastric marwadzo zvinoitika usiku kana chokuita ingestion vamwe zvokudya.

Kurambidzwa kushandiswa zvinodhaka

Zvino imi munoziva, kubva chii anobatsira "famotidine". Asi usati tora mushonga uyu, unofanira uzive nemirayiridzo. mishonga iyi contraindicated kugamuchira pa:

• lactation;
• muvana pasi makore matatu (muviri uremu asingasviki 20 kg);
• gestation;
• hypersensitivity kune famotidine, dzimwe blockers uye H2-histamine receptors.

With chinokosha Yambiro akati mishonga nachiremba hepatic kana renal insufficiency, immunosuppression, chiropa cirrhosis uye portosystemic encephalopathy muvana.

Sei kutora "famotidine"?

mishonga iyi ushandiswe mukati. Regai kutsenga mapiritsi, uye ndikandoshamba pasi zvakakwana uwandu emura.

Adults vaiona mushonga inofanira chete gadzai chiremba (zvichienderana uchapupu).

Panguva urikanwi pamusoro zvomudumbu turakiti, kunyanya rikwanise chokutambudzika uyewo nemaronda uye symptomatic gastroduodenite erosive vanoshingaira medicament dzinokurudzira kutora 20 MG kaviri pazuva, kana kamwe mari 40 MG (husiku). Kana kutsvakwa, nezuva chipimo chemushonga zvinodhaka zvinogona kugadziridzwa uye zvikava 80-160 MG.

Ya kurapwa pamwe mumiririri uyu vhiki 6-8.

Nokuti kudzivirirwa kubva urikanwi zvazvo zvinodhaka "Famotidine" contraindications dzakanga dzakanyorwa, 20 MG dzakabatwa kamwe pazuva, panguva yokurara.

Kana dyspepsia, iyo chokuita zvakawedzera secretion mudumbu, mishonga inokurudzirwa kutora nenguva chipimo chemushonga.

Kana refpyuks oesophagitis mishonga inoshandiswa kaviri pazuva 20-40 MG kwevhiki 6-12.

Kuti adzivise chido pamusoro gastric muto pasi vakawanda yokutindivadza medicament chinotarisirwa mune mari 40 MG manheru kana pakarepo asati kuvhiya.

Apo Zollinger-Ellison chirwere ari chipimo chemushonga uye ya chikumbiro yaro wakaiswa nomumwe. Kazhinji, kutanga dose zvinodhaka ndiko 20 MG. Tora mushonga uyu anofanira kuva maawa matanhatu ose. Kana waida, uwandu medicament anogona ngazviwedzerwe 160 MG nenguva kugamuchirwa maitikiro.

In pamberi renal kukundikana (semuenzaniso, CC Rine mamiririta asingasviki 30 paminiti) daily dosing zvinoreva anofanira kuderedzwa 20 MG.

Dosing muvana

Kubva chii anobatsira "famotidine" vana? Izvi zvinoreva vana basa nokuti chete nezvikonzero sezvo vakura. GI urikanwi ari exacerbation kuyaruka, uye reflux esophagitis inokurudzirwa kutora mishonga maererano zvinotevera zano: 2 MG pa 1 kg kurema muviri pazuva. Izvi kwazvo zvinodhaka rakakamurwa matanho maviri.

nemishonga

Vaiona rinoreva kungaita zvakadai nemishonga se:

• muromo yakaoma, arrhythmia, kuda kurutsa, mburwa vulgaris, kurutsa;
• alopecia, abdominal marwadzo, ganda yakaoma, bloating, kunoderedza BP, kupatira;
• ganda mapundu, manyoka, AV-chidhina, kudya zvirwere, angioedema;
• chiropa, kuvaviwa, yakakwirira chiropa makemikari, anaphylactic kuvhunduka;
• chenjera pfungwa nomuviri zvemwana asati, hypersensitivity zviratidzo, kutemwa;
• bronchospasm, dzungu, hyperthermia, kushaya hope, pokugara paresis;
• bradycardia, kufunganya, kuvhiringidzika, tinnitus, vasculitis;
• leukopenia, kurukutika, vakawedzera ropa urea yomuropa, aone zvinhu zvisipo, agranulocytosis, hope;
• thrombocytopenia mwoyo, hypoplasia, kutya, pancytopenia, psychosis;
• mwongo aplasia, madzerere, hyperprolactinemia;
• fivha, kurasikirwa libido, kurwadza kwemajoini, gynecomastia, kusabetsera, amenorrhea, tsandanyama pari.

Mutengo uye analogues

The Mari chigadzirwa ichi se "famotidine" anenge 30-55 rubles. Kana zvakakodzera, unogona kutsiviwa analogues akadai "Gastromaks", "Kvamatel", "Gastrotid", "ulfamid", "Famozol", "Famodingeksal", "Famosan".

mishonga Reviews

Drug "famotidine" - Vakawanda Anti-urikanwi mumiririri. Varwere vachitiwo zvinobudirira hworatidza pacharo mu zvirwere chokuita nemudumbu. Kakawanda iri nachiremba gastritis uye maronda.

Chimwe chakanakira kwezvinodhaka izvi hama kwayo cheapness.

Kana akaipa nezvaro, ipapo dzinowanzotaurwa chaizvo kugunun'una pamusoro divi migumisiro kurapwa.