"Klarotadin": mirayiridzo kushandiswa. Where kutenga "Klarotadin"? Kubva chii mapiritsi "Klarotadin"? Analogs "Klarotadina"

Neutachiona - musoro rakanyatsojeka akakodzera, kunyanya vabereki. Pashure pezvose, vakawanda vanonzi "chisimbwa" ari kuwedzera ose gore. Naizvozvo, isu funga ikozvino muudzame kugadzirira "Klarotadin". Mirayiridzo zvokushandisa achatanga kwataita zvinodhaka. Worth kuona pamberi kushandiswa. Buy "Klarotadin" chero chemishonga muguta renyu, uye pasina mushonga.

kana kushandisa

The medicament aitwe sema conjunctivitis, angioedema, pamwe urticaria (rikwanise chirwere uye idiopathic). The mushonga "Klarotadin" ndiyewo kunobudirira mugore rose kana mumwaka rhinitis; pseudoallergic kana Maitiro zvinokonzerwa histamine asunungurwa; anwa Tupukanana inoruma zvakasiyana; uyewo kuvaviwa dermatoses. The Pamazita anogona vaisanganisa.

Chii anogadzirwa

takurukura chigadzirwa "Klarotadin" -sirop. pamusoro pokushandisa zvaanotirayira achapiwa pazasi. Chipimo chemushonga - 5 MG / 5 Rine mamiririta. Loratodina (active chirungiso) mumwe milligram chete milliliter kuti manyuchi. Excipients: propylene glycol, shuga, benzoic acid, ethyl doro, cucumber acid, tropeolin, mvura Yakanatswa, zvokudya flavorings.

Inotengeswa dende rima regirazi, tinokwanisa imwe zana milliliters. dhudhumira ichi iri makadhibhokisi bhokisi. Mbuva anosanganisirawo rinokosha tambo chipunu.

Zvino funga piritsi "Klarotadin". Hwendefa nomumwe ane milligrams gumi loratodina. Kubva upiyona hwebetsero - MCC, lactose, karusiyamu stearate, glycolate, starch yavaibvisa. Mukavaisa Maronda akasiyana, mumwe nomumwe zvidimbu nomwe kana gumi. The makatoni zvingava munhu-packs it matatu kwamahwendefa.

pharmacodynamics

mushonga uyu ndowenyika H1-antihistamines, vasina anticholinergic uye nechepakati chiito. Kunotangira hafu yeawa pashure kunwa uye mabasa ose zuva. Zvakakosha kuti chirwere yaitonga kuti zvinodhaka asingadi kusaurayiwa nayo. Zvinofanira kucherechedzwa kuti nefuma loratodin dzaro metabolites havagoni zvinopfuura BBB.

Pharmacokinetics

Kana kudya, panguva yaunodya iri mishonga ndakarumbidzwa ari mugadziri, chikuru chinoumba loratodin nokukurumidza uye zvakazara wefodya unopinda muropa nemudumbu. Wevasungwa izvo zvinogona kare kuziva, azviise pasi Kuronga plasma maminitsi gumi nemashanu pashure kudya. Kana nguva kusvika Cmax muna yeplasma loratodina, izvozvo dzinosiyana awa imwe makumi mana nemaminitsi maawa maviri maminitsi matatu.

Asi nguva kusvika Cmax chacho vanoshingaira metabolite iri maawa anenge matatu. Just yeuka kuti mawa kushandiswa kwezvokudya pamwe mushonga anokwanisa kunetesa kubudirira Cmax loratodina uye chacho vanoshingaira metabolite mu yeplasma awa rimwe. Panguva iyoyowo Cmax aya zvinhu zvichava kuchinja, uye zvokudya haakwanisi chero nzira kufurira zvaizoitika.

Zvino vakwegura. "Klarotadin" (mirayiridzo chikumbiro manotsi), vanogona kubatwa pasina chinokosha Reservations pamusoro zera. Just yeuka kuti nguva kusvika Cmax ari yakawedzera maawa rimwe nehafu, mukusiyana kune vechidiki. Panyaya chidhakwa kukuvara chiropa, zvichienderana kwokuomerwa chirwere ukuwo vanobudirira rakawedzera Cmax.

Muna plasma kugutsikana loratodina chacho vanoshingaira metabolite rinosvika ruzhinji varwere mira chechetere pazuva rechishanu mushure ingestion. A nechisungo mapuroteni eplasma - 97%.

muviri

Chiropa loratodin tichishingaira fuma rinoita kuumba kushingaira metabolite dezkarboetoksiloratadina. Izvi kunoitika nokuda simba cytochrome P450 isoenzyme CYP3A4. Impact cytochrome P450 isoenzyme CYP2D6 uyewo chinobata, kunyange kune muduku pamwero. Kektonazol chipo, ndiko inhibitor pamusoro CYP3A4 zvinoita loratodinu dzikwanise dezkarboetoksiloratadin. Izvi imhaka zvinokonzerwa CYP2D6.

rutoto

WIthdrawal zvinodhaka "Klarotadin" (mirayiridzo kushandiswa uye rinotaurwa) Via itsvo, uyewo pamwe bile. Paavhareji T1 / 2 loratadine fuma iri maawa masere uye maminitsi makumi maviri (range zvingava maawa matatu kusvika makumi maviri). Panyaya yezviri metabolite, ayo avhareji iri maawa makumi maviri nemasere (range inogona kubva maawa matanhatu maminitsi makumi mana uye maawa matatu navanomwe).

MuMedhia akapiwa dezkaboetoksiloratadina iri maawa gumi uye maminitsi matatu (range, gumi nerimwe makumi matatu nemasere maawa). Kana chiri chiropa lesion doro, ari T1 / 2 kuchawedzera muwanze kwokuomerwa chirwere. Asi Varwere vane itsvo kutadza uye achirapwa hemodialysis, pharmacokinetics haanyanyi achinja.

pamuviri

Hazvigoni kutorwa nevakadzi vane pamuviri chinodhaka, nokuti "Klarotadin" vana vari mudumbu, anogona kukuvadza. Kana zvakava zvakakodzera kushandisa ichi mai zvinodhaka anoyamwa, ipapo zvakafanira kumisa achiyamwa sokuvapo kurapwa kwapera.

Contraindications

Kufanana nevamwe zvinodhaka ane contraindications uye "Klarotadin". Mirayiridzo application inoti mushonga harifaniri kushandiswa kana murwere ane hypersensitivity chero chezvinonhuwira gadziriro iyi. Pamuviri uye lactation zvinhu ezvinhu umo chishandiso hauna basa kana kugamuchira. Varwere vane chiropa kukundikana, vane kutora zvinodhaka "Klarotadin" nokungwarira.

nemishonga

Zvino zvakafanira kuudza sei izvi kunogona kukanganisa mushonga uri muviri womunhu. Possible zviratidzo tsinga zvirwere, kureva, kufunganya, asthenia, hyperkinesia, kushungurudzika mwana, somnolence, tremor, paresthesias, kuora mwoyo uye kukanganwa. Subcutaneous mafuta uye ganda vangabvuma mishonga yenhengo dermatitis.

Kana isu kutaura pamusoro genitourinary hurongwa, ipapo paari angava nokuchinja sedare weti, murwere anogona kunzwa kuti urinate, izvo zvichaita kuti pamwe nemarwadzo. Zvinogona kuva vaginitis, dysmenorrhea uye menorrhagia.

Pamusoro chikamu kwemakemikari anobudiswa maitiro uye zvichibvira nekukasika. Weight inogona hwakawedzera, murwere anonzwa nyota, uye zvowedzera vangadikitira. Zvetsandanyama nemapfupa Hurongwa kunogona kumbotambudzika vamwe hadzina kufambiswa zvakanaka mubasa ravo. gumbo iri chinyamunhari chinorwadza uye myalgia, uye arthralgia.

The zvomudumbu Hurongwa anogonawo kutambura. Kukanganisa kuravira, kupatirwa kana manyoka, kudya gastritis, fufune, wakawedzera kudya, stomatitis uye flatulence - zvose izvi neumwe mukana zvingaitika kana uchishandisa "Klarotadina".

Asingatani vakundikane uye kufema hurongwa. Kutyorwa vacharatidza sezvo bronchoconstriction, chikosoro, sinusitis, uye kuoma kwakaita mucous Kamudzira mumhino. Kunogonawo kuva conjunctivitis, anetseka chiratidzo, marwadzo munzeve uye maziso. Kumwoyo zvakare pasi marwadzo kuti vangapikisa sezvo palpitations, wakawedzera BP, uye kuderedza nayo.

Zviitiko neutachiona, richiratidzwa muchimiro angioedema, pruritus, urticaria uye photosensitivity. Ungazvidyawo kugamuchira musana marwadzo, fivha, hoarseness, muchipfuva marwadzo, chills, blepharospasm, uye kurwadziwa zamu.

Sezvaunogona kuona, kurutivi migumisiro inogona kunyatsonanga zvakakomba, saka regai kukanganwa nezvazvo. Consultation waida vaviri pamberi kwokubatsira mushonga wekutanga uye panyaya kuonekwa panguva pamusoro matambudziko.

Use uye chipimo chemushonga

Manyuchi uye mahwendefa "Klarotadin" kubva iyo - kunzwisisa. Ikozvino ngatitaurei pamusoro sei rinofanira kutorwa. zvinodhaka izvi zviri kuitirwa kuti pezviri kushandiswa. Vana vari vakuru gumi nemaviri, uyewo mukuru wacho varumbidzwa daily yaunodya ndiyo milligrams gumi. Izvi zviviri scoops mvura manyuchi kana mumwe piritsi. Asi vana vaviri kusvika gumi nemaviri, uremu muviri asingasviki matatu makirogiramu, Zvinokurudzirwa kutora milligrams mashanu. Uyu ndomumwe Scoop kana hafu piritsi. The daily dose haafaniri kupfuudza mufananidzo uyu. Kana kurema kupfuura makumi makirogiramu, kuti chipimo chemushonga zvichava zvakafanana vakura.

ovhadhozi

Kana musingadi Teerera zano kutora mushonga akawanda, anogona kukonzera zviratidzo zviri vakuru, iyo zvino richabatwa dzakanyorwa. tachycardia ichi, nomusoro uye hope. Uye vana vane uremu iri makirogiramu asingasviki matatu, ovhadhozi kungaita palpitations, uye extrapyramidal zviratidzo.

Kana murwere vakabvuma ovhadhozi, unofanira pakarepo kutaura chiremba. Zvinokoshawo kuti kutora matanho kuti ave nechokwadi chokuti mushonga abviswa nemudumbu uye Absorção de Água yakanga ipfupi. Izvi zvinoitwa kufurira emesis, gastric lavage, uye kushandiswa kusashanda kabhoni. Kana symptomatic kurapa kunogona kuitwa kudikanwa. Zvinofanira kurangarirwa kuti yezviri fuma iri loratadine hazvigoni vakaturikira vachiti kubva muviri hemodialysis. Uyewo, hapana mashoko ari excretion kuti maatomu akafanana izvi panguva peritoneal dialysis.

Kudyidzana nevamwe zvinodhaka

Kana tikashandisa mashoko "Klarotadin" iri muviri dose, potentiating mugumisiro doro kwakawanikwa. Uye pokushandisa zvinodhaka nemishonga yakadai se "Cimetidine", "Erythromycin" uye "ketoconazole" kuchawedzera wevasungwa ari plasma loratodina. Fani iyi hazvirevi kuratidza akaora, uye hakuna zvainoita kwemwoyo unonzi, electrocardiograph.

Pane uchapupu hwokuti inductors ose microsomal oxidation, izvo zvinosanganisira panyaya iyi, phenytoin, barbiturates, rifampicin, ziksorin, tricyclic antidepressants, phenylbutazone, anogona kuderedza kubudirira zvinodhaka ichi.

Zvokungwarira

Varwere vanotambura havachanyatsogoni hepatic basa, uye vane itsvo kutadza (glomerular filtration ane velocity asingasviki matatu Rine mamiririta / Nha), zvavakabvumirana kwokutanga dose "Klarotadin" haafaniri kupfuudza milligrams gumi (ndiko chete piritsi, kana vaviri kuyera nendiro manyuchi) nepakati zuva. Uyewo tinogona kupa mushonga uyu vana, vane zera idukusa makore maviri.

Vose vaya akatanga kutora mushonga uyu anofanira vakarega kwenguva ya mishonga yezvirongwa chero mhando zvinhu zvinogona nengozi kuti zvinoda yakakwirira yevasungwa uye psychomotor nokukurumidza zvavaifunga.

analogs

Hazvina kunaka kuti hapana mumwe mhando iri chinodhaka "Klarotadin". Analogues vane pazvipfuwo uye kupinza zvinodhaka. Zvakajairika yokumwe "vamwe" ndiwo mushonga "Claritin". ehupfumi ayo anenge akangofanana kuti zvinodhaka-vaiona kumusoro "Klarotadin". Price - ndicho musiyano mukuru. Mhiri kwemakungwa kugadzirira zvakati anodhura. The epamba mutengo ndiro, zvichienderana configuration. Saka, kurongedza 7 bv. Zvichaita mari anenge 100 rubles kavha metering gandiwa 10 x 3 -. Vangasvika 270 rubles, uye 100 ml manyuchi -. Vanenge 135 rubles.

Hatidi kuva pano kutaura chii kushandisa nani - "Klarotadin" kana "Claritin". Iri nyaya, uye iwe uchava kuzvifungira pachako, kutenga zvakachipa mudzimba chigadzirwa, kana kuti kupa kupfuura anodhura yokumwe. Asi zvinokosha kuziva kuti mumakore kwazvo-nekusimba chigadzirwa "Klarotadin". Saka Analogs ngapaonekwe ose zuva.

Chero zvazvingava, usati watanga kushandisa zvinodhaka izvi uye zvimwe saka kugadza vana vavo, vave nechokwadi kuti bvunza chiremba wako. Izvi achadzivirira kubva zvingangoitwa yakaipa kuti zvingaitika somugumisiro asingashiviriri nezvinodhaka, kushandisa zvisina kufanira kana ovhadhozi iwe. Zvinofanira kugara kurangarirwa kuti vakadaro Migumisiro kunogona kuchikosha kukanganisa utano hwako, utano vana venyu, uye upenyu hwenyu.