Hypovarianism, Zviratidzo neMarapirwo

Under ovarian hypofunction zvinoreva kunotoda izwi rinosanganisira zvirwere zvakasiyana muna etiology uye pathogenesis. Vose vane zvakafanana zviratidzo dzepabonde underdevelopment. Izvi zvinosanganisira kushaya mbereko, hypoplasia, amenorrhea, hypoestrogenism uye kushaya zvokudya zvinovaka muviri dumbu uye ovaries.

Kune mhando dzakawanda zvikuru hypofunction. Primary, chikuru, chiremba chimiro chirwere kumedza kutsenga kuchada kubereka. Kazhinji kunoitika vakadzi vakura kupfuura makore 35. The etiology chirwere basa guru siyana kwakaomarara dzezvakatipoteredza zvinhu. The mhaka chirwere chingava nemagene mutation, majini kubatwa, autoimmune zvirwere zviri ovaries.

Ovarian hypofunction kunogona kuitika pamusoro yaitwa kwomuzvarirwo kumwedzi uye rokubereka mabasa. Kunoratidza pacharo muchimiro kupiswa, amenorrhea, wakawedzera vangadikitira, kurukutika, utera, marwadzo mumwoyo uye musoro, nokuderedza kunyatsoshanda. Munguva panowanikwa chirwere anotsanangurwa: shoma kukura dumbu uye ovaries, pasi kuwanda estrogens uye prolactin, hapana follicles yellow miviri, yakakwirira follicle nekurukurirano uye luteinizing mahormone muropa. hypovarianism ichi ane kurapa kwakadaro: kushanda hormone (inonzi estrogen uye inonzi estrogen-progestin). Kemikari kurapa kunobatsira zvikuru mamiriro varwere, saka muna pave nechirwere zvakafanira kutanga kurapwa pakarepo.

Isolated (yechipiri) hypovarianism, makemikari uye dzichipfekeka kusagadzikana kushanda hypothalamic-pituitary hurongwa zvinokosha zvekuchipatara siyana zvakadai nyonganyonga. Pasinei nokuti ovaries akaona zvakajairika nhamba follicles, havaiti kuitika kuibvisa rikurumidze. Nokuti zvakadaro dzinoratidzwa: zvokudya zvinovaka, chikuru kana yechipiri amenorrhea, uterine uye ovarian hypoplasia, gipoestrogeniya. hypovarianism ichi Kazhinji inoitika pakanyorwa chakaipa zviri FSH uye luteinizing kemikari muropa.

Pane polycystic ovary syndrome. chirwere ichi chinobata anenge 3% yevakadzi vaduku. nyonganyonga yakadaro ichazivikanwa zvakawandisa kugadzirwa androgens (adrenal uye ovary), peripheral Kukundikana muviri wavo. Pamwe izvi zvinhu zvikaonekwa yakawanda luteinizing kemikari, zvakajairika kana yakaderera kuwanda pamusoro FSH, yakakwirira ropa kwevari prolactin. hypovarianism ichi, zviratidzo dzinoratidzwa kuvandudza pseudohermaphroditism, nokuti vakanga hyperandrogenism, clitoral hypertrophy, amenorrhea, kushaya mbereko, anovulation uye yakanyanya mburwa inozivikanwa.

Chimwe chikonzero, izvo zvinogona kuitika nokuda hypofunction pamusoro ovaries vangave virilizing ovarian anomera. Bundu masero ovaries zvinoumba yakawandisa testosterone, dehydroepiandrosterone uye androstenedione, izvo vanhurume mahormone. Clinical Kuratidza chirwere ndiyo kusavapo kumwedzi, mugari kumwedzi shoma (oligoopsomenoreya), acyclic uterine ropa. The chirwere dzinoratidzwa zviratidzo alopecia, hirsutism, kudzamisa nenzwi, paumbwe hono muviri mhando, paumbwe pseudohermaphroditism, hypertrophy pamusoro clitoris.

Kana pane hypovarianism, kurapwa anopiwa pashure misoro ongororo. Pakugadzirwa namamota akatakurwa mishonga, kupisa uye kuvhiya kubviswa bundu. Hormone Zvirwere vabatwe pashure kumbonyatsoongorora kuongorora siyana mahormone.