Codeine phosphate: mirayiridzo kushandiswa, analogs uye wongororo

Codeine ndohwaJehovha chinodhaka alkaloids akatevedzana. Vakawanda kushandiswa somushonga mushonga chikosoro. Rinoreva centrally nokuita mushonga rinowanzova ikashandiswa pamwe zvimwe zvinhu, pakati zviri terpin hydrate. Zvikuru dzinonakidza ndechokuti kushandiswa codeine anogona kuratidza zviratidzo zvinodhaka kudhaka. Akacherechedza uye marwadzo anokonzerwa. Panyaya iyi, codeine phosphate anogona kushandiswa rufimbi, asi zvakasimba kubudikidza mushonga.

mupfupi mashoko

Nheyo kushanda zvakafanana zvikuru codeine kuti morphine. Zvisinei, ayo unonyaradza marwadzo Marwadzo zvishoma kusimba. Pamwe chete ichi codeine phosphate (Latin Zvinoratidza fuma sezvo codeinum) ane iziviswe kukwanisa tikarega excitation chikosoro centre zvakasimba. Kuramba muenzaniso morphine Somuenzaniso, kuti ndoda mwoyo yevanhu mweya, uye kwete zvikuru kuchititadzisa basa nemudumbu. Pasinei neizvi, kazhinji pane zviitiko apo mushonga kunobatsira pamusoro muviri, kudzivisa hope.

Codeine phosphate: tsananguro contraindications

Kufanana nevamwe mishonga, codeine ane anoyevedza mazita contraindications. Vanofanira zvachose kuziva usati kushandisa fuma. Kuitira kuvandudza pfungwa dzenyu, isu nevamwe navo ari oga pasi. Saka, mushonga harifaniri kushandiswa pamberi zvinhu zvinotevera:

• High hypersensitivity;
• arrhythmia;
• kuzviuraya;
• intestinal matambudziko, kweprostate gland uye urethra;
• pamuviri kana lactation;
• Vakwegura kana vana zera;
• Zvichienderana Kuwanikwa zvinodhaka fuma inonzi codeine phosphate;
• manyoka;
• matambudziko rokuraradza;
• chepfu dispensiya;
• Kuvapo yokurwiswa Árbol asima;
• Kukuvara uropi, uyewo itsvo kana chiropa kukundikana.

Sezvaunogona kuona, mazita iwayo guru. Kazhinji, pamberi kushandiswa codeine vanofanira hazvo bvunza chiremba wako. Iye vanonyorera zvinokosha mushonga kana mamiriro muviri wako kunoita kuti kutora mushonga uyu.

Codeine phosphate: sei kutora uye chii mishonga?

Kana kushandisa codeine kwezvokurapa zvinangwa vanofanira kunyanya kungwarira kana drafting yakarurama chipimo chemushonga yamarudzi, uyewo nguva rubvumo yake. Saka, kana kuti kurwadziwa Zvinokurudzirwa kuti vakuru kutora 15-60 MG ose maawa 3-6. Kana manyoka ipfupi kuti chipimo chemushonga 30 MG kanokwana rimwe zuva. Pakupedzisira, apo chikosoro pfari vanofanira kunwa 10-20 MG zvinodhaka 4 kanomwe pazuva. Yakakwirira daily dose pamusoro codeine phosphate ayo (vane kunyora mushonga chiremba) ndiyo 120 MG.

Nokuti vana chipimo chemushonga zvishoma zvakasiyana. Kazhinji, nhamba iri kubva 0.5 MG pa 1 kg kurema muviri, kana toreva kudzvanyirira marwadzo siyana. Kana iwe kukosora iwe harifaniri kutora anopfuura 15 MG. Pakupedzisira, pamwe manyoka sezvo chipimo chemushonga iri 0.5 MG pa 1 kg kurema muviri. Achitaura kakawanda kugamuchirwa, ndizvo, sezvo vakuru, vanofanira kuva akaenzana 4-5 nguva zuva. Zviya, vana pasi kugamuchira codeine phosphate haina inokurudzirwa 2 years.

Pharmacological migumisiro

Sezvambotaurwa kare, codeine munhu centrally kuita antitussive. Ndezvenguva phenanthrene alkaloids pane akatevedzana. Uyezve, uyewo chokuita opioid Kanotokonya agonists kuti zvikuru anogona kuderedza excitability ari chikosoro centre, nokuda kwayo zvakananga chinovhiringidza. Unonyaradza marwadzo basa anogona kutsanangura fuma activation pamusoro opiate receptors kuti aratidze excitation munzvimbo dzakawanda nechepakati tsinga. Plus, uyewo anochinja nhamba mupfungwa manzwisisire kurwadziwa. Kazhinji, marwadzo mugumisiro pachena pacharo pashure 10-45 maminitsi mushure jekiseni, uye vachishandisa hafu yeawa kana uchishandisa mapiritsi codeine phosphate. Ya chiito rinovapo maawa anenge 4.

nemishonga

Chokwadi, codeine phosphate iine nemishonga, izvo wose anogona kuratidza nenzira dzakasiyana. Sezvo kuna contraindications, tinopa mazita zvinokonzerwa kazhinji anozviratidza pashure kushandisa fuma iyi:

• Tsinga anogona kukurirwa chiito chakadaro: wakawedzera hope, nomusoro uye dzungu (zvisingawanzoitiki), mukana zvisipo kana ziso zvinonyengera, kufunganya, kurota zvinotyisa kupinda hope, kuora mwoyo (isingawanzowanikwi kuwanika), uyewo pfari. Kana kunwa wokunzwa mishonga tinganetseka chakamira pakunodengenyeka zvine, Kuipa gwenya Kufambisa uye tsandanyama Rigidity.
• Munguva zvomudumbu hurongwa, zvinotevera migumisiro: svoto uye kurutsa (kashoma), kupatira, dumbu chinyamunhari chinorwadza, muromo yakaoma, zvingangoita neanorexia uye, pakupedzisira, hepatotoxicity.
• Cardio vascular hurongwa: arrhythmia, kungoerekana kuderera kana kuwedzera BP.
• Respiratoria maitiro: chinovhiringidza simba pamusoro kufema centre kana atelectasis.
• Panewo mukana wokuti inotevera neutachiona: mburwa, kuzvimba kumeso uye pahuro, kuvaviwa, bronchospasm, laryngospasm, uye urticaria.
• Mhiri migumisiro kubva pakushandisa codeine phosphate (muchiLatin, sezvinei, zvinoita codeinum) zvinosanganisira kunyanya vangadikitira, zvishomanana yokufara mamiriro. Uyewo ngozi nedoro pamwe refu mashoko kushandiswa (kunyanya akawanda).

Chokwadi, ngozi yekunwa nemishonga rakanyatsojeka diki. Hongu, uye kazhinji dzinosiyana chiito chimwe chinhu.

Zviratidzo ovhadhozi

zvinosanganisira zvinotevera mananara chirwere ovhadhozi: kuvhiringidzika mupfungwa, zvikuru dzungu, kutya uye utsinye, kugwinha, mukuru neutera muviri uye BP madonhwe. In Muzviitiko zvakaipisisa, pane mukuru ndingangokuvara nokurasikirwa pfungwa kana pakoma Pazvinotanga. Muropa kurapwa kana zvikashandiswa zvakapfurikidza kunogona refu zvikuru uye kwete nyore. Muzviitiko nomuchetura anofanira kugeza kunze mudumbu, kubata mweya wake uye kutsigira mwoyo basa. Mune zvimwe zviitiko, zvikuru musoro naloxone jekiseni, ndiro imwe antagonist pamusoro opioid analgesics.

Mirayiridzo Special munguva kurapwa

Kana pane kupora kwacho pashure codeine ovhadhozi kana kurapwa kwake muropa, varwere vanofanira kusanwa doro. Chokwadi ndechokuti panguva kurapa muvanhu zvishoma rakagomadzwa chinangwa uye kumhanya psychomotor siyana. Alcohol anogona chete sembura mamiriro kusimba. Uye kunogona kukanganisa munhu chokupika dzinogona ngozi mabasa.

Inofanira vainyatsotarisirwa panguva yepamuviri vakadzi. Zvechokwadi, kushandiswa codeine kunogona kukonzera kunonoka Ossificação em, uye dzimwe nguva pakarepo hurukuro - prolongation. Kazhinji, kuti majee pamwe yakaipa. Pakupedzisira, sezvataurwa pamusoro apa, vana vaduku, vose zvavo, hazvifaniri kutora codeine. Muchiitiko chino, pane wandei ndingangokuvara panowanikwa gangaidzo siyana, sezvo vana kwakawedzera aikanganiswa zvinokonzerwa opioid analgesics.

legality

MuRussia, pane ikozvino rugwaro, unokosha kune narcotics codeine. Naizvozvo, kutenga pane mishonga pasina mushonga haagoni kuva. Munguva ichangopfuura, kushandiswa codeine tsika vakatanga kuzivisa veruzhinji, sezvo vanhu vakawanda zvinodhaka riri kukura exponentially. Nenzira dzakawanda ichi "vakakodzera" ari American hudyu-hop vemifananidzo uyo kazhinji vanotsigira kushandiswa Purple akadhakwa - chokunwa chaiyo ine yakakwirira mishonga kuti codeine. manyuchi kwakadaro ane pinkish-yepepuru Hue, uye nei zita yakadaro kujairika. Mushure nokunwa mvura, iwe uchava kusangana kunzwa nounyoro euphoria dzakafanana kwazvo uye opiates, izvo, chokwadi, rinoreva codeine. Nziyo American rappers kazhinji ane wenyaya, achinongedzera hurongwa kushandisa Purple akadhakwa. Nenzira, musiki kufamba ichi - Dj Screw. Akafa pazera 29 kubva ovhadhozi kuti codeine.

Zvinofanira kucherechedzwa kuti codeine inowanikwa dzimwe mishonga, kusanganisira marudzi ose nefivhiri, protivomigrenoznye uye nevamwe. Panyaya iyi, mishonga yakawanda Zvakarambidzwa kutengeswa munharaunda Russia. Uye zvisiri pamutemo kuparadzirwa uye kutengeswa zvinogona kusimuka makore 12 ari mujeri.

In mhedziso

Codeine ane yakafara zvezvinotaurwa, sezvo migumisiro ayo pamusoro womunhu muviri simba chaizvo. Zvinogona ari kumbonyanya pfupi nguva kushandura omumwe huri munhu chaiko. Vakawanda muchimiro codeine (phosphate) - upfu iri nyore soluble mumvura. Nokuda ehupfumi ayo, rave richishandiswa nevakawanda mukurapa. Zvisinei, sezvo kazhinji kudaro opiates, nefuma seeped nokukurumidza munzira dzomumisha, ine inokanganisa vanhu dzichimuparadza payo, zvakaipira iyo kuti angatova kuurayisa.