"Amoxiclav 625": mirayiridzo kushandiswa, dzomuzana chaiwo

Pakati inorwisa utachiona vamiririri mukugadzirwa "Amoxiclav 625" murwere uchapupu uye nyanzvi kupfuura kuratidzwa. The mushonga ichaongororwa kuva mushonga kupfuura kwose kwose uye saka aifanira vakwanise kuzivikanwa. Nokuda akasiyana-siyana zvinoitwa, kuchengeteka vana nevakadzi lactating, "Amoxicillin-clavulanate" anofukidzira anenge zvachose munhu zvoupenyu empirical kurapa outpatient kufema uye Urinary zvirwere.

Release Highlights uye analogues

Kugadzirira "Amoksiklav 625" zvinoberekwa Slovenian naAmareki uye akaiswa sezvo zvinodhaka vanoshingaira fuma iri aminopenicillin amoxicillin uye clavulanic acid. Wokutanga kuridza basa mushonga uye asidhi kunodzivirira kwemabhakitiriya Beta-lactamases. Senzira "Amoksiklav 625 MG" Mahwendefa mushonga vanoumba 500 MG kuti mushonga, uye 125 MG ose clavulanate upiyona hwebetsero.

The gadziriro chete rinoita fuma amoxycillin yakabereka pasi dzakasiyana-siyana mazita. Chinonyanya Qualitative analogues ndedzinotevera akadzivirirwa aminopenicillin "Amoklav", "Augmentin", "Flemoklav", "Amklav", "Farmentin", "Amoksikar Plus", "wedzera", "Medoklav". Kunewo kudzivirirwa penicillins, vari analogues dzekirasi "Amoksiklava": "Amoxicillin", "Amoksikar", "Amosin", "Hikontsil" uye vamwe. kunyatsoshanda wavo anonzi zvinenge zvakafanana.

Chakakoshera mushonga

On kugadzirira "Amoxiclav 625" netsinhiro penyanzvi yakajeka zvikuru. Ichi Qualitative medicament, mumwe chete mishonga waiita inorwisa utachiona ayo kuburikidza pasi nemishonga inozivikanwa. Nokuda kwechikonzero ichi rinoshandiswa muzviitiko zvose umo amoxicillin zvakanga zvakakodzera. Uye "Amoxiclav" ndiye mumiririri zvinodhaka zvabatanidzwa. Zvinonzi anodzivirirwa clavulanic asidhi kubudikidza penicillinase, imwe enzayemu kuti anoparadza lactam chindori mushonga. Nemhaka kudzivirira "Amoxiclav" akatonyanya inoshingaira panyaya microbial masero.

umboo

Vasiyana mushonga "Amoxiclav 625" Chinyorwa rine nhungamiro nokuda zvinotapuriranwa, mishonga iyo anobvumirwa kushandisa mushonga unorwisa. Izvi kazhinji kutanga kufema, gastrointestinal, genitourinary zvirwere zviri nepakati nekuomarara. In munyoro marudzi zvakakodzera monotherapy, asi zvine mwero uye kwazvo anofanira kubatwa ari inpatient madzoro asingaurayiwi mubatanidzwa. Kazhinji, zvairatidza kuti kushandiswa "Amoxiclav 625 MG kuti" gadziriro gwaro rinotsanangura sezvinotevera:

• Zvirwere vaikudzwa kufema zvomukati (chirwere uye rikwanise siyana tonsillitis, pharyngitis, sinusitis, otitis nevezvenhau);
• zvirwere repasi kufema turakiti zvirwere (chakasimba uye chisingaperi siyana bronchitis, mabayo);
• kwemabhakitiriya zvirwere urogenital ino (pyelonephritis, urethritis, cystitis, oophoritis, pelvic kuzvimba, endometritis, mwandabvu, chancroid);
• chisingaperi osteomyelitis;
• ganda zvirwere, utachiona ikaruma mhuka, muchikuvadza Colonisation nemabhakitiriya;
• periodontitis.

Nokuti murwere, chikuru yokuwana mashoko pamusoro "Amoxiclav" gadziriro - mirayiridzo Chinyorwa. 625 MG zvinodhaka fuma, akasarudzwa triplicate munhu mukuru, unogona zvinobudirira kubata zvirwere kufema ezvinhu anokonzerwa giremu-akanaka advantageously kasvisto. Uye panguva Ari kurapwa nguva iri kazhinji mazuva 5-7.

Contraindications

The mushonga udzivirire chinyorwa uye pasi toxicity kirasi kuti penicillin hakurevi haabatanidzi kuvapo contraindications.

Vane mushonga shoma. Ivo vane ukama yokutsaukira pamberi concomitant zvirwere, sema maitiro kana vasiri mamiriro nhengo. Contraindications dzinosanganisira:

• Kuwanikwa chinoratidza panowanikwa cholestatic jaundice, vakawedzera aminotransferase basa kana kukura nehepatitis anokonzerwa kwokutanga kushanda "Amoksiklava", ayo analogs kana vamiririri boka penicillins;
• hepatic insufficiency, nhengo dzinobudisa neleukemia, mononucleosis nokuda achiipa ari nhamba nekuomarara nemishonga;
• sema sensitization kune mushonga kana yenhengo dzayo;
• zvinoratidza kuti kwaita pakarepo mhando neutachiona kana achitora zvimwe Beta-lactam inorwisa utachiona vamiririri;
• hama nguva contraindications: pamuviri muna 3rd trimester kuti lactation.

The pangozi yokuita Kurwara

Kana nhoroondo murwere pane panotaurwa omunharaunda mhando chisimbwa, "Amoxiclav" kwete basa. Kana dzakabudirira anaphylaxis kana angioedema mukupindura kugamuchira mumwe Beta-lactam inorwisa utachiona vamiririri, ari "Amoxicillin-clavulanate" haafaniri kugamuchirwa. Ipapo mushonga rwokusarudza ndiko mumiririri dzinoverengeka macrolides mune usinganyanyi kosi, kana fluoroquinolone.

dosing regimens

Huwandu zvinodhaka "Amoksiklav 625 MG," izvo zvinodiwa marapirwo anoenderana nezera uye kurema murwere. Zvirwere zvokufema rationally basa kusvika 2 magiramu kuti vakuru uye 1,3 magiramu kuyaruka. The "Amoxiclav" pane imwe dose ine 625 MG ndiyo chete kuyaruka uye mukuru zvinodhaka. Nokuti vana pasi makore 12, pane zvinodhaka panguva yakaderera mishonga.

Standard chipimo chemushonga munhu yairema makirogiramu 40 uye pamusoro 12 makore ari 625 MG kaviri pazuva. Adults makore makore 18 ushandiswe 625 MG katatu pazuva. Izvi zvakakwanira nokurapa mwero uye chiedza, kuti, outpatient zvirwere ganda, kufema, urogenital hurongwa. In zvirwere zvikuru basa 1000 MG (875 MG ose amoxycillin uye clavulanate 125) kaviri pazuva. Akabvumira katatu kushanda 1000 MG.

divi kushanda

Pasinei zvakakwana noupamhi kuchirapa chiito, pane vakawanda nemishonga. Vari chokuita omunharaunda kusagadzikana intestinal uye gastric mashandiro, uyewo nokuda kudhaka kuora zvivezwa masero kwemabhakitiriya, sezvo asingaurayiwi bactericidal kushanda.

The kupfuura kakawanda (1-10%) ndiwo nyaya kuda kurutsa, kurutsa kana manyoka kuitika mushure pokushandisa inorwisa utachiona pomutumwa. Uye vanoonekwa mazuva 2-4 mushure rubvumo. Sezvineiwo Kunowedzera ndingangokuvara dyspepsia hunotovapo kunetswa mune bowel tsika, uye zvimwe zvirwere muchiridzira: pfungwa nomuviri zvemwana asati pamwe excretory insufficiency, enteritis ezvinhu pashure resection mudumbu kana bowel, chisingaperi colitis.

Boka nguva nenguva yematambudziko (0,001-0,0001%) vari chiropa zvirwere: wakawedzera transaminases uye zvezvinangwa pamusoro hepatocyte cytolysis, cholestasis uye jaundice, leukopenia. Kakawanda angioedema, urticaria uye anaphylaxis iri kutaurwa. Chikonzero ichi ndicho zvishoma nezvishoma kuwedzera kwenhamba neutachiona nokuda mangwanani sensitization vana.

Gare gare, zvichaita hazvo kutungamirira zvinoderedza kukosha kuchirapa zvinodhaka "Amoxiclav". Mirayiridzo dzokushandisa 625-MG hwendefa haisati wairambidza kushandisa ekukurerai. Zvisinei, izvi zvinogona nokukurumidza kuitika. Ipapo iwe unofanira kutsvaka zvitsva mushonga kuti amino pamwe kunyatsoshanda zvakafanana. Sezvingatarisirwa, kuti chitsva kemikari rave synthesized uye vaedzwa, asi Implementation kwayo kusvikira zvoupfumi disadvantageous, nokuti "Amoxiclav" rinoita zvinodiwa vanachiremba.

Womuchato panguva pamuviri uye lactation

Maererano FDA mashoko, "Amoxiclav" haina teratogenic nomugumisiro. mhedziso iyi yakasvika pashure kuitisa tsvakurudzo mhuka, nokuti analogues vose mushonga akabatanidza Category B ne FDA (USA). Zvisinei, nokuda kufunga kutya kuti achiipa toxicosis "Amoxiclav 625" panguva pamuviri anenge asina basa pakutanga trimester. Muna II uye III trimesters kugamuchirwa kwayo anobvumirwa.

Aminopenicillin mu zvisaririra zvakafanana kupinda mukaka, izvo uchagumburwa nemudumbu pakati achangozvarwa. Zvisinei, zvinokosha yokutyora mumuviri wake, hazvina kukonzera, nokuti chii "Amoxiclav 625" haigoni kukanzura panguva lactation. The chete kunze ndivo zviitiko neutachiona mwana kana vulvovaginal mucous membranes kana zvomudumbu turakiti, zvichiguma kushanda "Amoxicillin". Zvadaro inoda kana zviri abolition amai kugamuchira chinhu inorwisa utachiona mumiririri, kana - panguva mucosal candidiasis - kwete breastfeed.

zvinodhaka chengetedzo mamiriro

Mahwendefa "Amoxiclav 625" vari zvine chakarondedzera kuchirapa chiito, saka tichidzivisa chepfu. Uyewo, hakuna nechepakati zvinokonzerwa nokuti chii chinogona kupiwa varwere inobudisa motokari kana zvimwe zvigadziriswe uchifamba. Iye haitungamiriri kutyorwa ndangariro, kuziva, kufunga, kana kufunga.

Zvisinei, pane chinhu ovhadhozi urwere zvinodhaka. zviitiko akadaro isingawanzowanikwi, uye anowanikwa bedzi muzviitiko zvisina kufanira chete dose 5 kana kupfuura magiramu zvinodhaka. Zviratidzo ndeizvi unhu: chemanyoka nepfungwa chokuita kwokuomerwa abdominal marwadzo, bloating, manyoka, kuda kurutsa uye dzimwe nguva kurutsa.

Kune nyaya crystalluria, iyo boka richitora mazamu pamwe yaunodya pamusoro amoxicillin, dzimwe nguva zvichiita kuti pave renal kukundikana. Zvisinei, Fani iyi inogona kuitika kana kugamuchira muviri chipimo chemushonga zvinodhaka. Zvinoreva nefroprotektsiya kurapwa uye dialysis, rinobvumira kubvisa ropa amoxicillin uye clavulanic acid.

matanho okudzivirira

Varwere nhengo dzinobudisa neleukemia, kana chirwere mononucleosis zvinodhaka "Amoksiklav 625", analogs uye generics kwete akaratidza nokuda mukuru mukana wokuti morbilliform nekumhanyirira. Uye nokuda kuderera kubudirira dzinogamuchidzanwa pamuviri panguva kurapwa "Amoxicillin" zvinodiwa mukwanisi ari kudzivirira vasingadiwi pamuviri chipingamupinyi nzira (makondomu).

With kukura manyoka panguva kushandiswa "Amoksiklava" Zvinoda nokubviswa mushonga uye Mabatirwo colitis (pseudomembranous kana Hemorrhagic). Pakadaro, ari kushanda ari inadmissible "Loperamide". Uyewo, kushanda kwenguva refu "Amoksiklava" hunoita kuti kukura vakawanda microbial nyuchi zvadzinoitwa tupukanana. Vanogona kukonzera matambudziko chirwere ichi.

Anozivikanwa zvinodhaka kwavatori

Urikozostatichesky mushonga "allopurinol" pamabiko pamwe "Amoksiklava" kunowedzera ngozi yokubatwa ganda rashes. Application urikozuricheskogo rinoreva "Probenecid", "oxyphenbutazone," "phenylbutazone", "sulfinpyrazone" kana acetylsalicylic asidhi akazoita hurumende ichiisa aminopenicillin (asi kwete clavulanic acid), nekuti icho zvishoma kunowedzera wevasungwa kuti mushonga mu ropa serum uye achawedzera zvachinokonzera.

Combination zvinodhaka "Amoksiklav 625 MG" pamwe bacteriostatic tupukanana safunga nokuda kwavo yakawiriranwa kudzvinyirira kunyatsoshanda. Other kugadzirira ine amoxicillin, uyewo zvinofanira kubatanidzwa bacteriostatic: chloramphenicol, macrolides, tetracyclines uye sulfonamides. Akabatana bactericidal mishonga kunotungamirira yakawiriranwa kuwedzera inorwisa utachiona basa.

Shandisa "Amoxiclav" panguva yokurapa, nemumuromo nhumbu zvaparadzwa nokuda njodzi yakawedzera nguva prothrombin uye thrombosis. In ichi pamuviri kushanda ari yekudyidzana ipfupi. Other chakarondedzera mishonga uyewo svitsanisa mugumisiro kuderedza kubudirira nemumuromo gadziriro pamuviri.

Kushandiswa "Amoksiklava" oportunisticheskih kubata zvirwere yomuka pamusoro yaitwa methotrexate kurapa, yekudyidzana anowedzera toxicity okupedzisira. Izvi zvinowedzera mukana kuti thrombocytopenia, leukopenia, ganda maronda, gastrointestinal maronda uye erosions. Zvadaro inokurudzirwa mapfumo aminopenicillin kushandiswa macrolides, kuramba uchida kurapwa pamwe methotrexate.

Kungofanana yakafara-chakarondedzera mushonga, "Amoxiclav" kunowedzera kunyatsoshanda kuti zvisina kunanga anticoagulants. Zvipatara "warfarin" nemhaka yokuremedzwa inorwisa utachiona vamiririri kubva utachiona kuti synthesize vhitamini K kunotungamirira kune vasanyanye prothrombin indekisi uye kwakawedzera INR. Zvinoguma wakakwirira pangozi ropa.

ZvoMutemo kukabatanidzwa inorwisa utachiona kurapa

Drug "Amoxiclav 625" uye ayo Generic dzomuzana anokwanisa kungawedzera mukana wokuti uite manyoka, kana kushandiswa nevamwe inorwisa utachiona nevamiririri. Chero makirasi inorwisa mabhakitiriya ine amoxicillin yekudyidzana vangangoona kukonzera manyoka, risingagoni kurapwa nokubatsira vanodzvinyirirwa peristalsis. gadziriro kwakadaro "loperamide" uye analogues ayo, contraindicated mu noutachiona manyoka. Muchiitiko chino, manyoka kunokonzerwa nokushandisa "Amoksiklava" anofanira kubatwa nemishonga.