"Lopedium" Mahwendefa: mirayiridzo manual, wongororo

"Lopedium" - mushonga nokuora mwoyo peristalsis. Chinonzi gelatin Kamudzira ane zvakaoma goko, aisiya pfumbu kana rima zvakasvibirira ruvara (kuine whitish homogeneous upfu) kana mahwendefa chena.

pharmacological ehupfumi

Mahwendefa "Lopedium" (mirayiridzo kushandiswa munyaya ino) akaumbwa imwe pfuma anogona kubatana intestinal opiate receptors. Kuburikidza ikoku nayo hwakaipa kusunungurwa acetylcholine uye prostaglandin. Nenzira iyi ine kupomba ipfupi chaizvo kunowedzera peristalsis uye kwenguva pakakoromoka ndima zvokudya achishandisa zvomudumbu turakiti. Uyewo intestinal masvingo Sechipanji zvakawanda zvinwiwa kuuya mataurire sphincter netsandanyama.

Pharmacokinetics

Vazhinji loperamide, vakapinda muviri Zvisinei muzvinhu paura,, nokuda nyanyisa vomuzana vanopfuura muviri, systemic bioavailable kunongova chikamu chimwe muzana.

Kuburikidza tsvakurudzo zvave kuwanikwa kuti mushonga ari kuparadzirwa panyaya intestinal rusvingo, uye nokudaro runokusunganidzai kuti receptors longitudinal tsandanyama jasi rukoko. Mostly loperamide anosunga kuti mapuroteni, kunyanya sealbumin.

Mahwendefa "Lopedium" (mirayiridzo Chinyorwa classifies pavo njodzi zvinodhaka) anenge yokuita zvinoitwa chiropa, apo vari rinoita, conjugated uye yabudiswa muna bile zvakakwana. Nokuda chaizvo kwakanyanya mugumisiro ndima yokutanga kuburikidza chiropa gadziriro, wevasungwa zvinodhaka muropa riri yekudyidzana akaderedzwa, apo kuramba yakaderera chaizvo. The mushonga iri yabudiswa zvachose kuburikidza gumi - gumi maawa.

zvairatidza

"Lopedium" (Mahwendefa) kudzidziswa Chinyorwa anokurudzira kuti panyaya chisingaperi uye rikwanise manyoka. mushonga uyu anogona kupiwa vanhu kunobatanidzwa vaifamba ( "nzvimbo manyoka"). Muchiitiko chino, kurapwa kunofanira mazuva maviri. Zvisinei, pane zvakaitika vasabatwa ropa iri pachituru haumanikidzwi kushandisa mushonga kuona zvinokonzera zvirwere chiremba.

Contraindications

Usashandisa mahwendefa chiitiko kuti pane hypersensitivity kune loperamide hydrochloride kana kune dzimwe zvinoumba kugadzirira.

Huru contraindications varwere:

- kwemabhakitiriya enterocolitis, kunokonzerwa mabasa zvimwe tusingaoneki:

- chenjera nemanyoka, achiperekedzwa reropa manyoka uye fivha.

Tikatora mushonga chero mishonga vanofanira nokungwarira zvikuru. Iva nechokwadi kutaurira chiremba wako.

Usashandisa mapiritsi "Lopedium" (mirayiridzo Chinyorwa anonyevera varwere) kukura kupatira, bloating kana intestinal mhingaidzo. Dzivisa mari kana zvakakodzera kudzivisa kudzvinyirirwa peristalsis.

Sei kutora "Lopedium" mahwendefa

The mushonga inogona kushandiswa vakuru nevana vakura kupfuura makore matanhatu. Kamudzira (piritsi) anofanira chimedzwe wose ane mvura shoma yakachena.

In chisingaperi uye rikwanise manyoka dose nevakura riri pakati 4 MG Pfungwa (hrs maviri.). Nokuti vana Zvakakwana kuti akaumbwa. The mushonga zvinofanira kutorwa pashure neimwe nzenza chetsoka. Kunonyanyisa zvazvingava daily vana uye nevakura matanhatu nemasere Mahwendefa.

Kana chenjera manyoka zviratidzo inonyangarika mumaawa makumi mana namasere, mushonga anofanira kumiswa.

Varwere vakwegura havafaniri chaiyo chipimo chemushonga kuchinja nguwani. The chete inoenda vanhu vachitambura kubva kusagadzikana neitsvo. "Lopedium" (Mahwendefa) kurayira Chinyorwa hariudzi kupa vana 3 makore.

Zvakakurukurwa kushanda

Kazhinji, Mabatirwo manyoka ndiye hurongwa. Kana murwere ane mukana rinotsanangura Mabviro ezwi chirwere, muchiitiko ichi zvakafanira kuita chaicho kurapwa. Zvinogoneka kuti chinodhaka chairayirwa chiremba munguva kushanda asingaurayiwi mishonga. In kufanana nokugamuchirwa kunoreva "Lopedium" (Mahwendefa) mirayiridzo kushandiswa kwevana rinokurudzira yokutsiva kurapa kuti muzadze electrolytes uye zvinwiwa. Izvi zvinofanira kuitwa chiitiko kuti kune kusaenzana kwezvinhu electrolytes uye kupera mvura mumuviri.

Varwere zvakawanikwa vawana immunodeficiency syndrome (AIDS), manyoka hwobva kurega kutora "Lopedium" pakuparwa bloating.

"Lopedium" (Mahwendefa): Instruction kushandiswa panguva yepamuviri uye achiyamwa

Vanachiremba havana kutokurudzira kutora mushonga kuvakadzi vane mimba uye lactating. Izvi imhaka yokuti uwandu loperamide duku kuonekwe mu mukaka. Ndokusaka vakadzi "rehurumende" vanofanira nguva dzose kubvunza chiremba usati watenga chezvinodhaka.

Kudyidzana nevamwe zvinodhaka

Masayendisiti muri nyaya kudyidzana zvinodhaka izvo vane pharmacological maitiro akafanana. Medicines kuti vane depressant migumisiro iri nechepakati tsinga, haagoni pamwe "Lopedium".

It rakaisirwa zviripo loperamide - ari substrate kuti P-glycoprotein. Mawa kushandiswa 'Lopedium "uye quinidine uye ritonavir kunogona kuwedzera ropa wevasungwa zvinodhaka. The dose anogona ngazviwedzerwe zviviri kana katatu. A ndozvinoitawo yaiitwa kana itraconazole uye ketaconazole.

Zvakaonekwa kuti mishonga kuva pharmacological ehupfumi yakafanana anogona kuwedzera kuitwa loperamide kanoverengeka. Asi zvinodhaka kuti rikurumidze muitiro kupfuura zviri nemudumbu, nekusiyana, kubudirira kwayo.

ovhadhozi

Mahwendefa "Lopedium" (mirayiridzo yokushandisa rinorondedzera zviratidzo ane ovhadhozi) zvingaita kuti kurasikirwa kufambisa, nomusoro, somnolence, ndivete uye Urinary chengetedzo. Kana wawana zviratidzo zvakafanana, unogona kutora "Naloxone". Mune zvisingawanzoitiki Muzviitiko, mudumbu yasukwa uye zvokunwa neactivated charcoal.

nenjodzi

On ganda mapundu ingangoumbwa, kusanganisira Stevenson-Johnson urwere; erythema multiforme; bundu; kuvaviwa uye mikoko.

The mushonga anogona kukanganisa pamusoro tsinga. Varwere tinganetseka hope, kurasikirwa kufambisa, kurasikirwa pfungwa, BP, uye tremor.

Kubva zvomudumbu hurongwa, varwere ungacherechedza yakaoma muromo, kupatira, kuda kurutsa, flatulence, kurutsa, ileus. Varwere vakawanda kuneta.

Nokungwarira yokunyanyisa inofanira kushandiswa vatyairi zvinodhaka uye kushandisa michina, sezvo mushonga anogona kukonzera hope.

Release chimiro, akafanana uye chiputiriso

Mumwe Kamudzira (Hwendefa) rine milligrams maviri loperamide hydrochloride. Kunze huru chinodhaka, uye kugadzirira rine ebetsero, kureva, talc, magnesium stearate, chibage starch uye lactose monohydrate.

Vakatengesa mapiritsi ari matete, zvidimbu gumi. The pasuru zvingava munhu shanu Maronda akasiyana.

Mahwendefa vane chena ruvara uye dzeraundi makavharidzira chimiro, convex rimwe divi.

The mushonga zvinofanira kuchengetwa nenzira rima, nzvimbo yakaoma pasigasvikirwi vana. The tembiricha haafaniri kupfuudza madhigirii maviri navashanu. pasherufu upenyu - makore mashanu kubvira musi gadzira. The mushonga inogona kutengwa chero chemishonga pasina mushonga. Asi usakanganwa kuti vaizviita kungaita kuti migumisiro yakaipa.